Chirimoya para Actividad antitumoral
Annona cherimola — 14 estudios científicos revisados
Preliminary¿Sirve Chirimoya para actividad antitumoral?
La investigación científica ha explorado el potencial de Chirimoya (Annona cherimola) en relación con actividad antitumoral. Se han identificado 14 estudios relevantes que examinan esta relación.
Compuestos activos involucrados: Alcaloides, Anonaina, Catequina, Conocido, Fenoles, Flavonoides, Glucósidos, Polifenoles, Quercetina, Saponinas, Terpenos, Glucósido, Compuestos fenólicos
Evidencia Científica
Los siguientes estudios han investigado la relación entre Chirimoya y actividad antitumoral:
Natural Products as Anticancer Agents.
Medicinal plants and mushrooms have always fascinated the world as an attractive source of natural compounds for cancer therapy. From ancient times, they have been valued as gourmet food and folk medicine in Oriental practice. For over 40 years, the world has witnessed the overwhelming interest of the western scientific fraternity in the pharmaceutical potential of natural products in combating cancer. The plants and mushrooms credited with success against angiogenesis and cancer metastasis belong to certain Plants, including Catharanthus roseus, Aloe Vera,Annona muricata,Curcuma longa, Withan
PubMed: 33390130Exploring the chemistry, biological effects, and mechanism insights of natural coumaroyltyramine: First report.
Today, pharmaceutical drugs have been shown to have serious side effects, while the bioactive components of botanical plants are proven to be effective in the treatment of several diseases marked by enhanced oxidative stress and mild inflammation, often associated with minimal adverse events. Coumaroyltyramine, designated by various nomenclatures such as paprazine, N-p-trans-coumaroyltyramine, p-coumaroyltyramine and N-p-coumaroyltyramine, could be a promising bioactive ingredient to address health issues thanks to its powerful anti-inflammatory and antioxidant effects. This review represents
PubMed: 39153554The pro-apoptotic effect of a Terpene-rich Annona cherimola leaf extract on leukemic cell lines.
BACKGROUND: The edible fruit Annona cherimola has previously shown many nutritional and medicinal properties. The current study evaluates the anti-cancer and anti-proliferative properties of Annona cherimola ethanolic leaf extract (AELE) on Acute Myeloid Leukemia (AML) cell lines cultured in vitro (Monomac-1 and KG-1). METHODS: The anti-proliferative effect of A. cherimola ethanolic leaf extract was evaluated via cell viability assay. Its pro-apoptotic effect was assessed through Cell Death ELISA and dual Annexin V/PI staining.
PubMed: 31830975Annona Genus: Traditional Uses, Phytochemistry and Biological Activities.
Species from the Annona (Anonaceae) genus are used in traditional medicine for the treatment of various diseases. Ethnobotanical studies provide information regarding the plant part and the preparation method being used, while scientific studies such as in vitro, in vivo, and clinical tests can provide evidence supporting ethnopharmacological reports, directing studies towards the isolation of compounds which may be active for specific pathologies. Annona muricata and Annona squamosa were the most commonly reported species from those studied, with Annona cherimola and Annona classiflora also s
PubMed: 32209036Pulp or Peel? Comparative Analysis of the Phytochemical Content and Selected Cosmetic-Related Properties of Annona cherimola L., Diospyros kaki Thumb., Cydonia oblonga Mill. and Fortunella margarita Swingle Pulp and Peel Extracts.
Fruit peels might be a valuable source of active ingredients for cosmetics, leading to more sustainable usage of plant by-products. The aim of the study was to evaluate the phytochemical content and selected biological properties of hydroglycolic extracts from peels and pulps of Annona cherimola, Diospyros kaki, Cydonia oblonga, and Fortunella margarita as potential cosmetic ingredients. Peel and pulp extracts were compared for their antiradical activity (using DPPH and ABTS radical scavenging assays), skin-lightening potential (tyrosinase inhibitory assay), sun protection factor (SPF), and cy
PubMed: 38474645Contexto Científico
En un estudio realizado a nivel de células (in vitro), se investigó la capacidad de los extractos de Annona cherimola para inhibir el crecimiento de líneas celulares cancerosas. Los resultados demostraron una reducción significativa en la viabilidad celular, sugiri el potencial antitumoral mencionado en la medicina tradicional.
Seguridad y Precauciones
El consumo de la chirimoya (Annona cherimola) requiere precaución debido a su compleja composición química, que incluye alcaloides y otros compuestos bioactivos. En el caso de mujeres embarazadas y en periodo de lactancia, no existe evidencia científica suficiente que garantice la inocuidad del consumo de la pulpa en concentraciones terapéuticas o masivas; por lo tanto, se recomienda limitar su ingesta a cantidades dietéticas normales para evitar la transferencia de metabolitos a través de la leche materna o posibles efectos sobre el desarrollo fetal. Respecto a la población infantil, los niños menores de 12 años deben consumir la fruta con moderación, principalmente debido al riesgo de presentar malestar gastrointestinal por la alta densidad de fibra y azúcares, así como por la posible sensibilidad a los compuestos fenólicos y saponinas presentes en la planta. En cuanto a interacciones farmacológicas, la presencia de compuestos con actividad biológica requiere vigilancia si se combinan con fármacos específicos. Por ejemplo, debido a la presencia de flavonoides y polifenoles que pueden influir en la coagulación, se debe tener precaución al administrar warfarina o anticoagulantes, ya que podrían potenciar o interferir con el control de la coagulación sanguínea. Asimismo, dado que la fruta contiene compuestos que pueden afectar el metabolismo de la glucosa, su consumo debe ser monitoreado en pacientes bajo tratamiento con metformina para evitar episodios de hipoglucemia.
Otras plantas estudiadas para Actividad antitumoral
Perfil completo: Ver todos los usos y evidencia de Chirimoya →