Artemisia para Tos y afecciones respiratorias
Artemisia argyi — 7 estudios científicos revisados
Moderate¿Sirve Artemisia para tos y afecciones respiratorias?
Uso documentado en la medicina tradicional y respaldado por investigación preliminar
Compuestos activos involucrados: Alcaloides, Fenoles, Flavonoides, Macromol, Polifenoles, Terpenos
Evidencia Científica
Los siguientes estudios han investigado la relación entre Artemisia y tos y afecciones respiratorias:
Artemisia argyi essential oil alleviates asthma by regulating 5-LOX-CysLTs and IDO-1-KYN pathways: Insights from metabolomics.
ETHNOPHARMACOLOGICAL RELEVANCE: Artemisia argyi essential oil (AAEO) is a traditional herbal remedy for asthma. However, the potential effect of AAEO on asthma has not been elucidated. AIM OF THE STUDY: To investigate the protective properties of AAEO upon asthma and elucidate its mechanism. MATERIALS AND METHODS: The effects of AAEO in asthma were assessed by histology and biochemical analysis. Then, we integrated real-time reverse transcription-quantitative polymerase chain reaction, enzyme-linked immunosorbent assay, immunohistochemistry and metabolomics analysis to reveal its mechanism.
PubMed: 38871010Artemisia argyi ethyl acetate fraction suppresses ovarian cancer progression via JUN/MAPK10 signaling: An integrated multi-omics investigation.
BACKGROUND: Artemisia argyi, a traditional Chinese medicinal herb widely applied in gynecology, has recently attracted interest for its pharmacological activities and emerging anti-tumor potential. PURPOSE: This study aimed to investigate the inhibitory effects and mechanisms of the ethyl acetate fraction (EA) of A. argyi on ovarian cancer (OvC). METHODS: Anti-proliferative and anti-migratory effects of EA were evaluated in OvC cell lines (A2780, SKOV3) using CCK-8, colony formation, wound healing, Hoechst 33,258 staining, Annexin V-FITC/PI apoptosis assay, and Western blotting. An A2780 xenog
PubMed: 41240544Artemisia argyi allelopathy: a generalist compromises hormone balance, element absorption, and photosynthesis of receptor plants.
BACKGROUND: Allelopathy is expressed through the release of plant chemicals and is considered a natural alternative for sustainable weed management. Artemisia argyi (A. argyi) is widely distributed throughout Asia, and often dominates fields due to its strong allelopathy. However, the mechanism of A. argyi allelopathy is largely unknown and need to be elucidated at the physiological and molecular levels.
PubMed: 35879664Artemisia Leaf Extract protects against neuron toxicity by TRPML1 activation and promoting autophagy/mitophagy clearance in both in vitro and in vivo models of MPP+/MPTP-induced Parkinson's disease.
BACKGROUND: Parkinson's disease (PD) is a neurodegenerative disorder involving the degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNpc). Cellular clearance mechanisms, including the autophagy-lysosome pathway, are commonly affected in the pathogenesis of PD. The lysosomal Ca HYPOTHESIS: This study aims is to investigate the neuroprotective effects of A. argyi in promoting the TRPML1-mediated autophagy/mitophagy-enhancing effect METHODS: In this study, we used 1-methyl-4-phenyl-pyridinium (MPP+)-induced PD model established in an SH-SY5Y human neuroblastoma cell lin
PubMed: 35752074Sesquiterpene lactone from Artemisia argyi induces gastric carcinoma cell apoptosis via activating NADPH oxidase/reactive oxygen species/mitochondrial pathway.
Apoptosis is an essential type of programmed cell death. Previous studies have demonstrated that a wide range of natural-derived anticancer agents induce apoptosis by trigging oxidative stress. Artemisia argyi is a traditional Chinese herb for treating diverse diseases including dyspepsia, arthroncus, and anaphylactic disease. In this study, sesquiterpene lactone 3 (SL3), a bioactive ingredient isolated from Artemisia argyi was found to show obvious inhibitory effect on two gastric carcinoma cells. Mechanism study revealed that SL3 promoted the membrane translocation of p47, activated nicotina
PubMed: 30075222Contexto Científico
Este estudio combinó métodos in vitro (en líneas celulares de cáncer como A2780 y SKOV3) e in vivo (en ratones con xenoinjertos de tumores). El cuarto estudio (PMod 35752074) exploró el efecto neuroprotector de los extractos de hojas de A.
Seguridad y Precauciones
El uso de Artemisia argyi debe abordarse con precaución debido a su compleja composición bioquímica, que incluye aceites volátiles, polifenoles y polisacáridos con actividad biológica significativa. En el caso de mujeres embarazadas y lactantes, el uso de esta planta está estrictamente desaconsejado. Aunque la investigación actual se centra en mecanismos celulares, estudios sobre fracciones de acetato de etilo han mostrado efectos sobre la señalización de la oxitocina y el metabolismo del ácido araquidónico, lo que sugiere una actividad hormonal potencial. Dado que se han observado efectos 'estrogénicos' (similares a los estrógenos) por parte de sus polisacáridos [PMID 39222778], existe un riesgo teórico de interferencia con el equilibrio hormonal necesario para mantener un embarazo saludable o para la lactancia. El uso de sustancias con actividad hormonal durante la gestación puede alterar el desarrollo fetal o la fisiología reproductiva.\n\nPara niños menores de 12 años, la seguridad de Artemisia argyi no ha sido establecida. Los sistemas enzimáticos y hormonales en desarrollo son altamente sensibles a los compuestos de la familia Asteraceae.
Otras plantas estudiadas para Tos y afecciones respiratorias
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