Artemisia para Potencial antimalárico

Artemisia lancea — 6 estudios científicos revisados

Preliminary

¿Sirve Artemisia para potencial antimalárico?

Al igual que otras especies del género Artemisia, se investiga su capacidad para contener compuestos similares a la artemisinina que pueden interferir con el ciclo de vida de parásitos como Plasmodium [PMID 16566952].

Compuestos activos involucrados: Aceite esencial, Eucaliptol, Terpenoides, Terpenos, Isopreno, ácidos grasos

Evidencia Científica

Los siguientes estudios han investigado la relación entre Artemisia y potencial antimalárico:

The history of qing hao in the Chinese materia medica.

Artemisinin is currently used for treating drug-resistant malaria. It is found in Artemisia annua and also in A. apiacea and A. lancea. Artemisia annua and A.

PubMed: 16566952

Anticancer properties of Artemisia species: mechanisms and experimental evidence.

The genus Artemisia (family Asteraceae) is widely recognized for its medicinal properties, among which artemisinin is the most notable, historically serving as a key antimalarial agent. Accumulating evidence now highlights the significant anticancer potential of Artemisia species, with bioactive compounds such as artemisinin and its derivatives exhibiting promising activity across multiple cancer types. This review provides a comprehensive overview of the molecular mechanisms underlying the anticancer effects of Artemisia-derived compounds, including apoptosis induction, cell cycle arrest, and

PubMed: 41860671

Neuroprotective and anti-epileptic potentials of genus Artemisia L.

The Genus Artemisia L. is one of the largest genera in the Asteraceae family growing wild over in Europe, North America, and Central Asia and has been widely used in folk medicine for the treatment of various ailments. Phytochemical and psychopharmacological studies indicated that the genus Artemisia extracts contain various antioxidant and anti-inflammatory compounds and possess antioxidant, anti-inflammatory, antimicrobial, antimalarial, and antitumor activity. Recently, increasing experimental studies demonstrated that many Artemisia extracts offer a great antiepileptic potential, which was

PubMed: 36339595

Artemisia: a promising plant for the treatment of cancer.

Due to the promising features of the ancient herbal plant Artemisia, its biologic activity has been investigated for use in modern medicine. In this regard, Artemisia and its active phytochemicals have been introduced as having antimalarial, antioxidant, cytotoxic, antispasmodic, anthelmintic, neuroprotective, anti-inflammatory, and antimicrobial agents. In the case of cancer treatment, the plant species and its bioactive compounds target multiple pathways. Here we reviewed the scientific literature published up until 2018, which have explained the cytotoxic activity of the Artemisia species a

PubMed: 31784199

Phytochemistry and pharmacological activity of the genus artemisia.

Artemisia and its allied species have been employed for conventional medicine in the Northern temperate regions of North America, Europe, and Asia for the treatments of digestive problems, morning sickness, irregular menstrual cycle, typhoid, epilepsy, renal problems, bronchitis malaria, etc. The multidisciplinary use of artemisia species has various other health benefits that are related to its traditional and modern pharmaceutical perspectives. The main objective of this review is to evaluate the traditional, modern, biological as well as pharmacological use of the essential oil and herbal e

PubMed: 33893998

Seguridad y Precauciones

El uso de Artemisia lancea debe abordarse con extrema cautela debido a la presencia de compuestos bioactivos como el eucaliptol (1,8-cineole) y el alcanfor, los cuales pueden presentar toxicidad en dosis elevadas. En el caso de mujeres embarazadas y en periodo de lactancia, no se recomienda su consumo. La falta de estudios clínicos robustos en humanos sobre la seguridad fetal hace que el riesgo de efectos teratogénicos (malformaciones congénitas) o alteraciones en el desarrollo embrionario sea una preocupación válida. Durante la lactancia, existe el riesgo de que los terpenoides se transfieran a través de la leche materna, lo que podría afectar el desarrollo neurológico del lactante o alterar su patrón de sueño debido a las propiedades estimulantes de ciertos componentes. Para niños menores de 12 años, el uso debe evitarse estrictamente. Los sistemas enzimáticos y metabólicos en desarrollo de los infantes son más sensibles a los compuestos volátiles; el alcanfor, en particular, puede tener efectos neurotóxicos si se absorbe en cantidades significativas.

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