Murici para Astringente

Byrsonima verbascifolia — 6 estudios científicos revisados

Preliminary

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La investigación científica ha explorado el potencial de Murici (Byrsonima verbascifolia) en relación con astringente. Se han identificado 6 estudios relevantes que examinan esta relación.

Compuestos activos involucrados: Alcaloides, Flavonoides, Saponina, Saponinas, Taninos, Terpenos

Evidencia Científica

Los siguientes estudios han investigado la relación entre Murici y astringente:

Screening of Brazilian medicinal plants for antiviral activity against rotavirus.

ETHNOPHARMACOLOGICAL RELEVANCE: Brazilian medicinal plants traditionally used for the treatment of diarrhoea were investigated for their in vitro antiviral activity against the simian rotavirus SA11. MATERIALS AND METHODS: The ethanolic crude extracts of plants collected in the cerrado of Minas Gerais, Brazil were submitted to phytochemical screening. The cytotoxicity of the extracts was inferred by cellular morphologic alterations. Antiviral activity was assessed by the ability of the extracts to inhibit the cytopathic effect (CPE) of rotavirus on the treated cells. RT-PCR was performed to co

PubMed: 22469769

Gestational exposure to Byrsonima verbascifolia: teratogenicity, mutagenicity and immunomodulation evaluation in female Swiss mice.

ETHNOPHARMACOLOGICAL RELEVANCE: Byrsonima verbascifolia is used in folk medicine to treat diarrhea, intestinal infections, chronic wounds, Chagas disease, inflammation and as a diuretic. However there is no investigation regarding the Byrsonima verbascifolia hydrometanolic extract (BVHME) used during gestation. MATERIALS AND METHODS: The pregnant females were randomly divided into 5 groups. Control group received saline plus DMSO (1%) in a volume of 0.1 mL/10 g (b.w.), via gavage, for at least 15 days prior to mating and throughout the gestational period. The Pre-treatment group received the B

PubMed: 24140582

Modulatory effect of Byrsonima verbascifolia (Malpighiaceae) against damage induced by doxorubicin in somatic cells of Drosophila melanogaster.

Byrsonima verbascifolia, popularly known in Brazil as murici, is a medicinal plant widely used in the treatment of bacterial and viral infections, Chagas's disease, diarrhea, bronchitis, cough and fever, as well as for protection of the intestinal mucosa. Since chemotherapy and radiotherapy, broadly employed in the treatment of cancer, can have undesirable side effects, such as inducing DNA damage in normal cells, it would be useful to investigate compounds that inhibit or reduce these effects. A lyophilized water extract of murici, used at three different concentrations (25, 50, and 100 mg/mL

PubMed: 20092036

Anti-inflammatory effects of the butanolic fraction of Byrsonima verbascifolia leaves: Mechanisms involving inhibition of tumor necrosis factor alpha, prostaglandin E(2) production and migration of polymorphonuclear leucocyte in vivo experimentation.

The leaves of Byrsonima verbascifolia (Malpighiaceae) are traditionally used to treat various diseases including inflammatory conditions. The main goal of this study was to evaluate the in vivo anti-inflammatory activity of the polar constituents from the butanolic fraction of B. verbascifolia leaves (BvBF), as well as to investigate the mechanisms involved in the anti-inflammatory activity. The polar constituents were identified by liquid chromatography coupled to diode array detector and mass spectrometry (LC-DAD–MS) and matrix-assisted laser desorption/ionization – time-of-flight mass spect

PubMed: 26724477

Phytochemical screening, total phenolic content and antioxidant activity of Byrsonima species.

The species of the Byrsonima genus (Malpighiaceae) have been used in folk medicine to treat gastrointestinal disorders, asthma and skin infections. In this study, the total phenolic content, antioxidant activity and phytochemical screening were carried out in polar extracts of Byrsonima coccolobifolia, Byrsonima verbascifolia and Byrsonima intermedia. The presence of tannins and flavonoids in the samples and high phenols content was observed. B. coccolobifolia and B.

PubMed: 25604883

Contexto Científico

En términos sencillos, el extracto de la planta mostró la capacidad de detener el virus en un entorno controlado de laboratorio, lo que valida científicamente parte de su uso tradicional para tratar diarreas.

Seguridad y Precauciones

La seguridad en el uso de Byrsonima verbascifolia (Murici) debe abordarse con extrema cautela debido a la escasez de ensayos clínicos controlados en humanos, lo que limita nuestra capacidad de establecer protocolos de dosificación seguros. En relación con el embarazo y la lactancia, no existe evidencia científica suficiente que garantice la ausencia de efectos teratogénicos (anomalías en el desarrollo fetal) o alteraciones en la composición de la leche materna. Dado que la planta contiene metabolitos secundarios como saponinas y taninos, que pueden cruzar la barrera placentaria o excretarse en la leche, se recomienda evitar su consumo terapéutico en estas etapas para prevenir riesgos potenciales no cuantificados. Para la población pediátrica, específicamente niños menores de 12 años, el uso debe ser evitado; sus sistemas metabólicos, especialmente el hígado y los riñones, están en desarrollo y la toxicidad de los alcaloides y terpenos presentes en la planta podría comprometer la función enzimática inmadura. En cuanto a las interacciones farmacológicas, se debe prestar especial atención a los pacientes que consumen warfarina (anticoagulantes), ya que los compuestos fenólicos y flavonoides presentes en el fruto pueden alterar la agregación plaquetaria o el metabolismo hepático, intensificando el riesgo de hemorragias. Asimismo, existe un riesgo potencial de interacción con la metformina debido a la presencia de compuestos que podrían alterar la absorción intestinal o la respuesta glucémica, y con fármacos antihipertensivos, dado que los efectos antioxidantes y astringentes podrían potenciar o interferir con la regulación de la presión arterial.

Ver perfil de seguridad completo de Murici →

Otras plantas estudiadas para Astringente

Perfil completo: Ver todos los usos y evidencia de Murici →