Murici para Diarrea viral (rotavirus)
Byrsonima verbascifolia — 4 estudios científicos revisados
Moderate¿Sirve Murici para diarrea viral (rotavirus)?
Los extractos de la planta contienen taninos, flavonoides y saponinas que muestran actividad antiviral in vitro, inhibiendo la formación del efecto citopático causado por el virus [PMID 22469769].
Compuestos activos involucrados: Alcaloides, Flavonoides, Saponina, Saponinas, Taninos, Terpenos
Evidencia Científica
Los siguientes estudios han investigado la relación entre Murici y diarrea viral (rotavirus):
Screening of Brazilian medicinal plants for antiviral activity against rotavirus.
ETHNOPHARMACOLOGICAL RELEVANCE: Brazilian medicinal plants traditionally used for the treatment of diarrhoea were investigated for their in vitro antiviral activity against the simian rotavirus SA11. MATERIALS AND METHODS: The ethanolic crude extracts of plants collected in the cerrado of Minas Gerais, Brazil were submitted to phytochemical screening. The cytotoxicity of the extracts was inferred by cellular morphologic alterations. Antiviral activity was assessed by the ability of the extracts to inhibit the cytopathic effect (CPE) of rotavirus on the treated cells. RT-PCR was performed to co
PubMed: 22469769Modulatory effect of Byrsonima verbascifolia (Malpighiaceae) against damage induced by doxorubicin in somatic cells of Drosophila melanogaster.
Byrsonima verbascifolia, popularly known in Brazil as murici, is a medicinal plant widely used in the treatment of bacterial and viral infections, Chagas's disease, diarrhea, bronchitis, cough and fever, as well as for protection of the intestinal mucosa. Since chemotherapy and radiotherapy, broadly employed in the treatment of cancer, can have undesirable side effects, such as inducing DNA damage in normal cells, it would be useful to investigate compounds that inhibit or reduce these effects. A lyophilized water extract of murici, used at three different concentrations (25, 50, and 100 mg/mL
PubMed: 20092036Antiviral and antimicrobial activities of Colombian medicinal plants.
Strong antiviral and antimicrobial activities were detected in methanolic extracts of 24 plants used medicinally in the treatment of skin infections in four different regions of Colombia. Thirteen extracts displayed activity against herpes simplex virus (HSV) whereas none was active against poliovirus. The antiviral activity was indicated by a total inhibition of viral cytopathic effects (CPE) at a non-cytotoxic concentration of the extract. The most potent extract was obtained from Byrsonima verbascifolia (L.) HBK. which showed anti-HSV activity at a concentration as low as 2.5 microg/ml.
PubMed: 11535363A potential antiviral against COVID-19 obtained from Byrsonima coccolobifolia leaves extract.
In this study, we specifically focused on the crude methanolic leaf extract of Byrsonima coccolobifolia, investigating its antifungal potential against human pathogenic fungi and its antiviral activity against COVID-19. Through the use of high-performance liquid chromatography coupled with electrospray ionization ion trap tandem mass spectrometry, direct infusion electrospray ionization ion trap tandem mass spectrometry, and chromatographic dereplication procedures, we identified galloyl quinic acid derivatives, catechin derivatives, proanthocyanidins, and flavonoid glycosides. The broth dilut
PubMed: 38211642Seguridad y Precauciones
La seguridad en el uso de Byrsonima verbascifolia (Murici) debe abordarse con extrema cautela debido a la escasez de ensayos clínicos controlados en humanos, lo que limita nuestra capacidad de establecer protocolos de dosificación seguros. En relación con el embarazo y la lactancia, no existe evidencia científica suficiente que garantice la ausencia de efectos teratogénicos (anomalías en el desarrollo fetal) o alteraciones en la composición de la leche materna. Dado que la planta contiene metabolitos secundarios como saponinas y taninos, que pueden cruzar la barrera placentaria o excretarse en la leche, se recomienda evitar su consumo terapéutico en estas etapas para prevenir riesgos potenciales no cuantificados. Para la población pediátrica, específicamente niños menores de 12 años, el uso debe ser evitado; sus sistemas metabólicos, especialmente el hígado y los riñones, están en desarrollo y la toxicidad de los alcaloides y terpenos presentes en la planta podría comprometer la función enzimática inmadura. En cuanto a las interacciones farmacológicas, se debe prestar especial atención a los pacientes que consumen warfarina (anticoagulantes), ya que los compuestos fenólicos y flavonoides presentes en el fruto pueden alterar la agregación plaquetaria o el metabolismo hepático, intensificando el riesgo de hemorragias. Asimismo, existe un riesgo potencial de interacción con la metformina debido a la presencia de compuestos que podrían alterar la absorción intestinal o la respuesta glucémica, y con fármacos antihipertensivos, dado que los efectos antioxidantes y astringentes podrían potenciar o interferir con la regulación de la presión arterial.
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