Cañafístula para Hiperglucemia (control de azúcar en sangre)
Cassia grandis — 5 estudios científicos revisados
Moderate¿Sirve Cañafístula para hiperglucemia (control de azúcar en sangre)?
Actúa como inhibidor de la enzima α-glucosidasa y de la lipasa pancreática, lo que reduce la absorción de carbohidratos y grasas [PMID 30766429].
Compuestos activos involucrados: Alcaloides, Fenoles, Flavonoides, Polifenoles, Saponinas, Terpenos
Evidencia Científica
Los siguientes estudios han investigado la relación entre Cañafístula y hiperglucemia (control de azúcar en sangre):
Effects including photobiomodulation of galactomannan gel from Cassia grandis seeds in the healing process of second-degree burns.
The epithelium recovery of skin-burned wounds has been currently achieved by several therapies, for example, hydrogel-based dressings and photobiomodulation therapy (PBMT). Thus, this work aimed to evaluate the healing activity of Cassia grandis seeds' galactomannan gel, associated or not with PBMT, in second-degree burns. Sixty male Wistar rats were assigned to four groups: Control (CG), Gel (GG), Laser/PBMT (LG), and Laser+Gel (GLG). Burns were made with an aluminum bar (90 °C), and submitted to clinical observations diary and area measurements at specific days. Microscopic analysis was base
PubMed: 37567532Influence of Cassia grandis galactomannan on the properties of sponge cakes: a substitute for fat.
Here we have proposed to evaluate potential replacers of fat in sponge cake formulations. Our investigation consisted initially of monitoring the physical-chemical changes in sponge cake batters caused by gradually replacing the vegetable fat/margarine of a control sample (standard sponge cake recipe) with galactomannan extracted from the seeds of Cassia grandis. Several samples were prepared where a 100% concentration of vegetable fat was substituted with galactomannan in different concentrations. We then compared both microscopic and macroscopic characteristics of pure fat cake batter formul
PubMed: 29632933Immobilization of bioactive compounds in Cassia grandis galactomannan-based films: Influence on physicochemical properties.
Galactomannan extracted from Cassia grandis seeds was used for the production of films containing different concentrations of the bioactive compounds lactoferrin (LF), bioactive peptides (BAPs), and phytosterols. SEM, FTIR, mechanical and thermal properties, colour, moisture content (MC), solubility, water vapour permeability (WVP), and contact angle (CA) were performed evaluating the effect of increasing concentrations of bioactive compounds on the films' physicochemical properties. The immobilization of bioactive compounds leads to films with roughness on their surface, as observed by SEM. T
PubMed: 28049015A medicinal herb Cassia alata attenuates quorum sensing in Chromobacterium violaceum and Pseudomonas aeruginosa.
UNLABELLED: Quorum sensing (QS) has been shown to play a crucial role in the pathogenesis in many bacteria, and attenuation of QS is one of the targets of antimicrobial therapy with particular interest in combating drug resistance. This study reports the QS inhibitory activity of metabolites from Cassia alata L. (Ca. alata), an important medicinal herb widely used in the treatment of microbial infections. For investigating the QS inhibition (QSI), the potential of Ca.
PubMed: 28035685Medicinal plants and their isolated phytochemicals for the management of chemotherapy-induced neuropathy: therapeutic targets and clinical perspective.
BACKGROUND: Chemotherapy, as one of the main approaches of cancer treatment, is accompanied with several adverse effects, including chemotherapy-induced peripheral neuropathy (CIPN). Since current methods to control the condition are not completely effective, new treatment options should be introduced. Medicinal plants can be suitable candidates to be assessed regarding their effects in CIPN. Current paper reviews the available preclinical and clinical studies on the efficacy of herbal medicines in CIPN. METHODS: Electronic databases including PubMed, Scopus, and Cochrane library were searched
PubMed: 30852764Seguridad y Precauciones
El uso de Cassia grandis debe abordarse con extrema precaución debido a su potente actividad biológica. En el caso de mujeres embarazadas y en periodo de lactancia, no existe evidencia científica que garantice la seguridad del consumo de sus extractos; por el contrario, sus efectos laxantes intensos podrían provocar desequilibrios electrolíticos y deshidratación, lo cual es contraproducente para la salud gestacional. La lactancia también representa un riesgo, ya que los compuestos bioactivos pueden excretarse en la leche materna, afectando al lactante. Para niños menores de 12 años, el uso está estrictamente desaconsejado, especialmente por su potencial efecto sobre el metabolismo de la glucosa y su acción purgante, que podría comprometer el desarrollo nutricional y el equilibrio hídrico de un organismo en crecimiento. En cuanto a interacciones farmacológicas, se debe tener especial cuidado con la metformina y otros hipoglucemiantes, dado que la planta posee efectos inhibidores de la α-glucosidasa y de la lipasa, lo que podría potenciar excesivamente la reducción de los niveles de azúcar en sangre (hipoglucemia) [PMID 30766429]. Asimismo, su potencial efecto sobre la regulación de la glucosa podría interferir con tratamientos para la diabetes.
Perfil completo: Ver todos los usos y evidencia de Cañafístula →