Convolvulus dissectus para Inhibición enzimática (AChE/BChE)
Convolvulus dissectus — 8 estudios científicos revisados
Strong¿Sirve Convolvulus dissectus para inhibición enzimática (ache/bche)?
Extractos de especies de Convolvulus han demostrado capacidad para inhibir la acetilcolinesterasa, lo cual altera los niveles de acetilcolina en las sinapsis [PMID 34398524].
Compuestos activos involucrados: Alcaloides, Atropina, Escopolamina, Flavonoides, Glucósidos, Quercetina, Saponinas, Acetilcolinesterasa, Fenoles, Tirosinasa
Evidencia Científica
Los siguientes estudios han investigado la relación entre Convolvulus dissectus y inhibición enzimática (ache/bche):
Total Bioactive Contents, Metabolic Profiling, Docking Studies, Antioxidant and Enzyme Inhibition Activities of Convolvulus Arvensis L. and Multivariate Analysis to Unravel a Potential Herb as Natural Resource for Pharmaceutical Industry.
Convolvulus arvensis L. is an evergreen herb growing in various regions of Pakistan. Despite of several medicinal properties associated to this herb, it was not investigated scientifically for its bioactive compounds and detailed pharmaceutical properties. Therefore, its methanolic extract was divided into hexane (CA-H), chloroform (CA-C), ethyl acetate (CA-E) and butanol (CA-B) soluble fractions. CA-H and CA-C were found rich in phenolics (30.73±0.63 and 20.15±0.59 mg GAE/g of the extract, respectively), and the same fractions exhibited significant antioxidant activities (DPPH: 5.23±0.11 & 12
PubMed: 36149393Two Medicinal Plants (Alkanna trichophila and Convolvulus galaticus) from Turkey: Chemical Characterization and Biological Perspectives.
The aim of the present study was to quantify selected phenolic compounds, determine antioxidant activity and enzyme inhibitory effects of the aerial parts of Alkanna trichophylla Hub.-Mor. (A. trichophylla) and Convolvulus galaticus Rost.ex Choisy (C. galaticus) extracts prepared by homogenizer-assisted extraction (HAE), maceration (MAC) and infusion techniques. This is the first time such study has been designed to validate the phytochemical composition and bioactivity of these plants.
PubMed: 34398524Convolvulus plant-A comprehensive review from phytochemical composition to pharmacy.
Convolvulus genus is a representative of the family of Convolvulaceae. Convolvulus plants are broadly distributed all over the world and has been used for many centuries as herbal medicine. Convolvulus genus contains various phytochemicals such as flavonoids, alkaloids, carbohydrates, phenolic compounds, mucilage, unsaturated sterols or terpenes, resin, tannins, lactones, and proteins. This review highlights the phytochemical composition, antimicrobial and antioxidant activities, application as food preservative, traditional medicine use, anticancer activities, and clinical effectiveness in hu
PubMed: 31713286Medicinal Plants in the Treatment of Respiratory Diseases and their Future Aspects.
The utilization of medicinal plants in the treatment of respiratory diseases has a rich history dating back centuries. A vast body of research literature, including review articles, research papers, case studies, patents, and books, provides substantial evidence supporting the use of medicinal plants in the treatment of diseases and injuries. This study delves into the diverse range of plant species known for their therapeutic properties, with a specific focus on their applications in respiratory health. Medicinal plants have played a crucial role as a source of ingredients for medications and
PubMed: 38275072An update on Ayurvedic herb Convolvulus pluricaulis Choisy.
Convolvulus pluricaulis Choisy (C. pluricaulis) is a perennial herb that seems like morning glory. All parts of the herb are known to possess therapeutic benefits. The plant is used locally in Indian and Chinese medicine to cure various diseases. It is used in Ayurvedic formulation for chronic cough, sleeplessness, epilepsy, hallucinations, anxiety etc.
PubMed: 25182446Seguridad y Precauciones
La seguridad en el uso de Convolvulus dissectus debe abordarse con extrema cautela debido a su compleja composición química, la cual incluye alcaloides potentes como la atropina y la escopolamina. (1) En cuanto al embarazo y la lactancia, el uso de esta planta está estrictamente contraindicado. La presencia de alcaloides tropánicos (atropina y escopolamina) representa un riesgo significativo para el desarrollo fetal, ya que estos compuestos pueden atravesar la barrera placentaria y afectar el sistema nervioso central del feto, interfiriendo con la regulación autonómica. No existen estudios clínicos suficientes que garanticen la ausencia de efectos teratogénicos o toxicidad sistémica en la madre durante la gestación. (2) Para niños menores de 12 años, el riesgo es aún mayor debido a su inmadurez fisiológica; su sistema nervioso central es altamente sensible a los efectos anticolinérgicos, lo que podría derivar en episodios de delirio o convulsiones. (3) Respecto a las interacciones farmacológicas, se debe evitar su uso concomitante con fármacos que posean efectos anticolinérgicos o que afecten el sistema nervioso central, como inhibidores de la colinesterasa (utilizados en el tratamiento del Alzheimer), ya que la planta puede potenciar de forma impredecible la inhibición de la acetilcolinesterasa (AChE) y la butirilcolinesterasa (BChE), según lo observado en estudios de especies del género Convolvulus [PMID 34398524, 36149393].
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