Dichrostachys para Citotoxicidad celular (en concentraciones específicas)

Dichrostachys cinerea — 4 estudios científicos revisados

Preliminary

¿Sirve Dichrostachys para citotoxicidad celular (en concentraciones específicas)?

Estudios con extractos de tallo completo mostraron efectos citotóxicos en líneas celulares de riñón de mono, sugiriendo potencial daño celular si la dosis no es controlada (PMID 30947717).

Compuestos activos involucrados: Flavonoides, Glucósidos, Lípido, Saponinas, Taninos, Terpenoides, Terpenos, Compuestos fenólicos

Evidencia Científica

Los siguientes estudios han investigado la relación entre Dichrostachys y citotoxicidad celular (en concentraciones específicas):

In vitro and in vivo studies on anti-malarial activity of Commiphora africana and Dichrostachys cinerea used by the Maasai in Arusha region, Tanzania.

BACKGROUND: Traditional medicinal plants are one of the potential sources of anti-malarial drugs and there is an increasing interest in the use and development of traditional herbal remedies for the treatment of malaria and other ailments. This study was carried out with the aim to investigate the phytochemical screening, cytotoxic effect and antiplasmodial activities of Dichrostachys cinerea and Commiphora africana. Both plants are used by the Maasai in Tanzania in suspected malaria and other diseases. No previous work appears to have investigated the potential anti-malarial activity of the t

PubMed: 30947717

Clinical evaluation of Veerataru (Dichrostachys cinerea Linn.) in the management of Mootrakruchchhra (Dysuria).

Veerataru is quoted to be effective in various conditions of Mootravaha Srotodushti such as Mootrakruchchhra (Dysuria), Mootraghata (Anuria), Ashmari (Urinary calculi), Sharkara (Concretions) etc., by various Acharyas. Mootrakruchchhra (Dysuria) is a disease of Basti (Bladder). It comes under Mootraapravruttijanyavyadhi, where Kruchchhrata (Shoola -Pain and Daha-Burning) during mootra pravrutti is the chief symptom. As per modern view, dysuria is a leading feature of lower or mid urinary tract infection. Antibiotics have their own limitations due to re-infections and recurrence even after long

PubMed: 24501517

Ethnomedicinal plants used for treatment of snakebites in Tanzania - a systematic review.

CONTEXT: Snake envenomation is one of the neglected health problems in Tanzania. Since most people, especially in rural areas, suffer from its burden, their cases are not documented due to reliance on medicinal plants. Despite the pivotal role of medicinal plants in treating snakebites, there is a paucity of information. OBJECTIVE: This review documents medicinal plants used to treat snakebites in Tanzania. MATERIALS AND METHODS: A systematic search using electronic databases such as PubMed, Google Scholar, Scopus, Science Direct and grey literature was conducted to retrieve relevant informati

PubMed: 36205572

Endorsement and phylogenetic analysis of some Fabaceae plants based on DNA barcoding.

BACKGROUND: DNA barcoding have been considered as a tool to facilitate species identification based on its simplicity and high-level accuracy in compression to the complexity and subjective biases linked to morphological identification of taxa. MaturaseK gene (MatK gene) of the chloroplast is very vital in the plant system which is involved in the group II intron splicing. The main objective of this study is to determine the relative utility of the "MatK" chloroplast gene for barcoding in 15 legume as a tool to facilitate species identification based on their simplicity and high-level accuracy

PubMed: 35655052

Seguridad y Precauciones

La seguridad en el uso de Dichrostachys cinerea es un tema de extrema precaución debido a su potente actividad biológica sobre el tejido muscular liso. En el contexto de embarazo y lactancia, el uso de esta planta está estrictamente contraindicado. Investigaciones realizadas en modelos animales han demostrado que los extractos de la corteza de D. cinerea aumentan significativamente la fuerza de contracción y la frecuencia de las contracciones del miometrio (el músculo uterino), actuando de manera similar a la oxitocina (PMID 25914041). Este efecto oxitócico o de inducción de contracciones puede provocar un parto prematuro o complicaciones obstétricas graves en mujeres gestantes. No existe evidencia de que sea seguro para la lactancia, ya que los compuestos bioactivos podrían transferirse al lactante.

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