Cabezona para Complicaciones de diabetes
Eryngium carlinae — 6 estudios científicos revisados
Protección hepatorrenal en ratas diabéticas; efecto antioxidante [pmid 37371966] [pmid 30917540]¿Sirve Cabezona para complicaciones de diabetes?
La investigación científica ha explorado el potencial de Cabezona (Eryngium carlinae) en relación con complicaciones de diabetes. Se han identificado 6 estudios relevantes que examinan esta relación.
Compuestos activos involucrados: β-Farneseno, β-Pineno, Calameno, α-Farneseno, Flavonoides, Ácidos fenólicos, Saponinas triterpénicas, Pineno, Saponinas, Taninos, Terpenos, Compuestos fenólicos
Evidencia Científica
Los siguientes estudios han investigado la relación entre Cabezona y complicaciones de diabetes:
An Ethyl Acetate Extract of Eryngium carlinae Inflorescences Attenuates Oxidative Stress and Inflammation in the Liver of Streptozotocin-Induced Diabetic Rats.
Secondary metabolites such as flavonoids are promising in the treatment of non-alcoholic fatty liver disease (NAFLD), which is one of the complications of diabetes due to oxidative stress and inflammation. Some plants, such as Eryngium carlinae, have been investigated regarding their medicinal properties in in vitro and in vivo assays, showing favorable results for the treatment of various diseases such as diabetes and obesity. The present study examined the antioxidant and anti-inflammatory effects of the phenolic compounds present in an ethyl acetate extract of the inflorescences of Eryngium
PubMed: 37371966Protective Effect of the Hexanic Extract of Eryngium carlinae Inflorescences In Vitro, in Yeast, and in Streptozotocin-Induced Diabetic Male Rats.
In the present study, we investigated the composition and antioxidant activity of the hexanic extract of Eryngium carlinae inflorescences by employing in vitro assays to measure antioxidant capacity and 2,2-diphenyl-1-picrylhydrazyl scavenging activity. We also applied the hexanic extract to Saccharomyces cerevisiae, under hydrogen peroxide-induced stress. Finally, we tested the extract in male Wistar rats with and without streptozotocin-induced diabetes. The compounds in the hexanic extract were analyzed by gas-chromatography-mass spectrometry, which revealed mainly terpenes and sesquiterpene
PubMed: 30917540Abnormalities in lipid metabolism, associated with increased risk of cardiovascular disease (CVD), frequently occur in people with diabetes.
PubMed: 31829771Hypolipidemic Activity of Eryngium carlinae on Streptozotocin-Induced Diabetic Rats.
Diabetes mellitus (DM) is a significant risk factor for the development of cardiovascular complications. This study was undertaken to investigate the effect of chronic administration of ethanolic extract of Eryngium carlinae on glucose, creatinine, uric acid, total cholesterol, and triglycerides levels in serum of streptozotocin- (STZ-) induced diabetic rats. Triglycerides, total cholesterol, and uric acid levels increased in serum from diabetic rats. The treatment with E. carlinae prevented these changes.
PubMed: 22162811Antioxidant effects of silver nanoparticles obtained by green synthesis from the aqueous extract of Eryngium carlinae on the brain mitochondria of streptozotocin-induced diabetic rats.
Diabetes mellitus is a metabolic disorder characterized by chronic hyperglycemia that affects practically all tissues and organs, being the brain one of most susceptible, due to overproduction of reactive oxygen species induced by diabetes. Eryngium carlinae is a plant used in traditional Mexican medicine to treat diabetes, which has already been experimentally shown have hypoglycemic, antioxidant and hypolipidemic properties. The green synthesis of nanoparticles is a technique that combines plant extracts with metallic nanoparticles, so that the nanoparticles reduce the absorption and distrib
PubMed: 36988777Seguridad y Precauciones
Eryngium carlinae no ha presentado efectos tóxicos significativos en los estudios preclínicos publicados hasta la fecha. La CC50 de 356 µg/mL establecida en líneas celulares Caco-2 indica un margen de seguridad citotóxica razonable para los extractos metanólicos [PMID 29681972]. Las hojas y brácteas intensamente espinosas de esta planta pueden causar lesiones mecánicas dolorosas durante la recolección y manipulación del material fresco. Se recomienda enfáticamente el uso de guantes gruesos durante la cosecha silvestre. Algunos compuestos del tipo furanocumarinas, reportados en varias especies del género Eryngium, podrían causar fotosensibilidad cutánea al contacto con el jugo de la planta seguido de exposición solar. Se recomienda precaución y evitar la exposición solar directa durante las horas siguientes al uso tópico de preparaciones frescas.
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