Gastrodia para Crisis epilépticas o convulsiones

Gastrodia elata — 5 estudios científicos revisados

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¿Sirve Gastrodia para crisis epilépticas o convulsiones?

Contiene compuestos fenólicos con potencial anticonvulsivo que actúan sobre la excitabilidad neuronal, similar a algunos fármacos antiepilépticos (PMID 27765372).

Compuestos activos involucrados: Fenoles, Flavonoides, Gastrodina, Saponinas, Terpenos, Compuestos fenólicos

Evidencia Científica

Los siguientes estudios han investigado la relación entre Gastrodia y crisis epilépticas o convulsiones:

Gastrodia elata Blume: A review of its mechanisms and functions on cardiovascular systems.

Gastrodia elata Blume (GEB), commonly called Tianma in Chinese, is a valuable and extensively used herbal Traditional Chinese Medicine with a wide range of clinical applications. It has been used to treat headaches, dizziness, stroke, epilepsy, amnesia, spasm, and other disorders since ancient times. Hundreds of compounds, including phenols, glycosides, polysaccharides, steroids, organic acids, and others, have been isolated and identified from this plant. Modern pharmacological studies have shown that its active ingredients possess many pharmacological effects, such as neuroprotective, analge

PubMed: 37075984

Gastrodia elata and epilepsy: Rationale and therapeutic potential.

BACKGROUND: Gastrodia elata Blume (G. elata) is a traditional Chinese herb used for centuries in folk medicine. Due to the claimed anticonvulsant properties of G. elata, it is expected that this herb continues to be a target of research, aiming to deepen the available knowledge on its biological activity and safety. PURPOSE: The current review aims to discuss the most recent advances on the elucidation of the phytochemical composition and anticonvulsant potential of G.

PubMed: 27765372

The rhizome of Gastrodia elata Blume - An ethnopharmacological review.

ETHNOPHARMACOLOGICAL RELEVANCE: Gastrodia elata Blume (Orchidaceae) is commonly called Tian ma in Chinese and mainly distributed in the mountainous areas of eastern Asia, such as China, Korea, Japan and India. It is an extensively used traditional Chinese herbal medicine in the clinical practice of traditional Chinese medicine, to treat headache, migraine, dizziness, epilepsy, infantile convulsion, tetany and so on. The present paper reviews the advancements in investigation of botany and ethnopharmacology, phytochemistry, pharmacology, toxicology and quality control of Gastrodia elata Blume.

PubMed: 27377337

Review on pharmacological effects of gastrodin.

Gastrodia elata Blume is a well-known traditional Chinese medicine that is mainly used to treat diseases related to the nervous system, such as stroke, epilepsy, and headache. Gastrodin is the main bioactive component of Gastrodia elata Blume, and studies have shown that it has extensive pharmacological activity. This narrative review aims to systematically review relevant studies on the pharmacological effects of gastrodin to provide researchers with the latest and most useful information. Studies have shown that gastrodin has prominent neuroprotective effects and can treat or improve epileps

PubMed: 37749449

The processing methods, phytochemistry and pharmacology of Gastrodia elata Bl.: A comprehensive review.

ETHNOPHARMACOLOGICAL RELEVANCE: Gastrodia elata Bl. (GE) is one of the rare Chinese medicinal materials with a long history of medicine and cooking. It consists of a variety of chemical components, including aromatic compounds, organic acids and esters, steroids, saccharides and their glycosides, etc., which has medicinal and edible value, and is widely used in various diseases, such as infantile convulsions, epilepsy, tetanus, headache, dizziness, limb numbness, rheumatism and arthralgia. It is also commonly used in health care products and cosmetics. Thus, its chemical composition and pharma

PubMed: 37187361

Seguridad y Precauciones

El uso de Gastrodia elata (conocida tradicionalmente como Tianma) requiere una precaución extrema debido a su potente actividad sobre el sistema nervioso central y cardiovascular. En cuanto al embarazo y la lactancia, no existe evidencia clínica suficiente en humanos que garantice la seguridad del consumo de sus compuestos, como la gastrodina, en mujeres gestantes; por lo tanto, su uso está estrictamente contraindicado en estas etapas. El riesgo potencial radica en que los componentes bioactivos podrían atravesar la barrera placentaria y afectar el desarrollo neurológico fetal o alterar el equilibrio hormonal. De igual manera, durante la lactancia, no se debe administrar debido al desconocimiento de su transferencia a través de la leche materna y su impacto en el lactante. Para niños menores de 12 años, el uso no está recomendado, ya que los sistemas neurológico y metabólico en desarrollo son altamente sensibles a los efectos sedantes y anticonvulsivos de la planta, lo que podría interferir con el desarrollo cognitivo normal. En cuanto a las interacciones farmacológicas, existe un riesgo significativo de interacción con la warfarina y otros anticoagulantes; dado que la planta puede influir en procesos hematológicos, podría potenciar el efecto de estos fármacos, aumentando el riesgo de hemorragias.

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