Mentha para Toxicidad sistémica dosis-dependiente

Mentha longifolia — 10 estudios científicos revisados

Moderate

¿Sirve Mentha para toxicidad sistémica dosis-dependiente?

El consumo de compuestos como la pulegona puede generar efectos tóxicos en diversos sistemas del cuerpo si se superan los umbrales de seguridad [PMID 25284948].

Compuestos activos involucrados: Flavonoides, Mentol, Pulegona, Terpenoides, Terpenos, ácido, Isopreno

Evidencia Científica

Los siguientes estudios han investigado la relación entre Mentha y toxicidad sistémica dosis-dependiente:

Endophytic actinobacteria from Mentha longifolia and Lonicera nummulariifolia: a novel source against antibiotic resistance.

BACKGROUND: The escalating global challenge of antibiotic resistance severely restricts our ability to treat common infectious diseases, necessitating the urgent need for the development of novel antibiotics with distinct mechanisms of action. Actinobacteria, a diverse group of bacteria with medical, industrial, pharmaceutical, and ecological significance, produce approximately two-thirds of clinically used antibiotics. Endophytic actinobacteria (EA), residing within various plant species, represent a promising source for discovering novel antibiotics to combat this raising threat. This study

PubMed: 40563081

Pharmacological activity of Mentha longifolia and its phytoconstituents.

Current paper reviews the pharmacological activities, therapeutic indications and phytochemicals of M. longifolia. This herb has been consumed traditionally for the treatment of various diseases, including gastrointestinal disorders, respiratory disorders, infectious diseases, inflammatory diseases, as well as menstrual disorders. In the modern era, various pharmacological activities have been confirmed for M. longifolia, such as anti-parasitic, antimicrobial, anti-insect, antimutagenic, antinociceptive, anti-inflammatory, antioxidant, keratoprotective, hepatoprotective, anti-diarrhea, and spa

PubMed: 32188234

Mentha longifolia assisted nanostructures: An approach to obliterate microbial biofilms.

Microbes maneuver strategies to become incessant and biofilms perfectly play a role in scaling up virulence to cause long-lasting infections. The present study was designed to assess the use of an eco-friendly formulation of functionalized silver nanoparticles generated from Mentha longifolia leaf extract (MℓE) for the treatment of biofilm-producing microbes. Nanoparticles synthesized using MℓE as a reducing agent were optimized at different strengths of AgNO3 (1 mM, 2 mM, 3 mM, and 4 mM). Synthesis of M. longifolia silver nanoparticles (MℓAgNPs) was observed spectrophotometrically (450 nm) sh

PubMed: 38985793

Effect of

BACKGROUND AND OBJECTIVES: Today, medicinal plants and their derivatives are considered to reduce the prevalence of antibiotic resistance. The aim of this study was to investigate the effect of MATERIALS AND METHODS: A total of 50 clinical strains of RESULTS: CONCLUSION: Based on the results of this study, it was observed that supplementing

PubMed: 39267932

Chromosome-level genome assembly of Mentha longifolia L. reveals gene organization underlying disease resistance and essential oil traits.

Mentha longifolia (L.) Huds., a wild, diploid mint species, has been developed as a model for mint genetic and genomic research to aid breeding efforts that target Verticillium wilt disease resistance and essential oil monoterpene composition. Here, we present a near-complete, chromosome-scale mint genome assembly for M. longifolia USDA accession CMEN 585. This new assembly is an update of a previously published genome draft, with dramatic improvements. A total of 42,107 protein-coding genes were annotated and placed on 12 chromosomal scaffolds.

PubMed: 35551385

Seguridad y Precauciones

La seguridad del uso de Mentha longifolia debe abordarse con cautela debido a su compleja composición química, que incluye compuestos como la pulegona, mentona y mentol. En el contexto de embarazo y lactancia, el uso de esta planta debe evitarse o estar estrictamente supervisado por un profesional de la salud. La presencia de pulegona, un componente clave identificado en estudios de farmacología [PMID 25284948], ha sido asociada en diversas especies de Mentha con efectos potencialmente abortivos o de estimulación uterina si se consumen en dosis elevadas. No existen estudios clínicos suficientes en humanos que garanticen la seguridad del consumo de extractos de M. longifolia durante la gestación, por lo que la precaución es la norma. En cuanto a niños menores de 12 años, la administración de aceites esenciales o extractos concentrados de esta planta no es recomendable.

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