Limonaria para Actividad analgésica
Murraya paniculata — 5 estudios científicos revisados
Moderate¿Sirve Limonaria para actividad analgésica?
En términos simples, esto significa que la planta ayuda a reducir la inflamación y el daño en las articulaciones al bloquear las señales químicas que causan el dolor y la hinchazón.
Compuestos activos involucrados: Alcaloides, Cubenol, Flavonoides, Luteolina, Metilsalicilato, Saponinas, Terpenos
Evidencia Científica
Los siguientes estudios han investigado la relación entre Limonaria y actividad analgésica:
Diversity in Phytochemical Composition and Medicinal Value of Murraya paniculata.
Murraya paniculata is herbal medicinal plant which is traditionally being used for management of cardiovascular, intestinal and respiratory (air way) disorders. This evergreen plant of tropical regions is a member of Rutaceace family. The goal of this review is to analyze and report the biological activities and active phytochemicals reported from Murraya paniculata (M. paniculata) extracts and essential oil. The data was searched using different search engines and using specific key words including M.
PubMed: 36529712Murraya paniculata (L.) (Orange Jasmine): Potential Nutraceuticals with Ameliorative Effect in Alloxan-Induced Diabetic Rats.
Orange jasmine, Murraya paniculata (Rutaceae), is a plant from India widely used in folk medicine as antinociceptive, antiinflammatory, and antioxidant. Although oral hypoglycemic agents and insulin are the mainstays of treatment of diabetes mellitus (DM), there is a significant demand for new natural products to reduce the development of diabetic complications. Alloxan-induced diabetic rats were treated for 60 days with a hydroalcoholic extract of M. paniculata (MPE), at doses of 100, 200, and 400 mg/kg. MPE decreased glycemia and also cholesterol and triglyceride levels, starting 1 week afte
PubMed: 28840616A comprehensive review of the botany, phytochemistry, pharmacology, and toxicology of Murrayae Folium et Cacumen.
Ethnopharmacological relevance: Murrayae Folium et Cacumen (MFC) is a plant considered to be a traditional Chinese medicine with culinary value as well. The dry leaves and twigs of Murraya paniculata and M. exotica are used to treat stomach aches, rheumatism, toothaches, swelling, and insect and snake bites. They are also used to prepare spicy chicken dishes. Aim of the review: This review comprehensively summarizes the available information on the botanical characterization, phytochemistry, pharmacological activities, pharmacodynamics, pharmacokinetics, and toxicity of MFC.
PubMed: 38606170Total flavonoids extracted from the leaves of Murraya paniculata (L.) Jack prevents acetaminophen-induced liver injury by activating Keap1/Nrf2 and PI3K/AKT/mTOR signaling pathway.
ETHNOPHARMACOLOGICAL RELEVANCE: In regions such as China and Southeast Asia, leaves of the traditional Chinese medicinal herb Murraya paniculata (L.) Jack are highly valued for their ability to detoxify and reduce swelling, promote blood circulation, and alleviate pain. These properties are harnessed in traditional healing practices, where the herb is aligned with the liver and stomach meridians in Chinese medicine. Consequently, extracts from the leaves of Murraya paniculata (L.) Jack are believed to ameliorate various liver-related ailments. Despite its widespread use, there is a paucity of
PubMed: 40020792Comparison of the preventive effects of Murraya exotica and Murraya paniculata on alcohol-induced gastric lesions by pharmacodynamics and metabolomics.
ETHNOPHARMACOLOGICAL RELEVANCE: Multi-source phenomenon is very common for traditional Chinese medicine (TCM). Both Murraya exotica L. (ME) and Murraya paniculata (L.) Jack (MP) are used as the source plants of Murrayae Folium et Cacumen (MFC), a traditional Chinese medicine recorded in Chinese Pharmacopoeia for promoting qi and relieving pain, mainly for the treatment of stomach pain, rheumatism and arthralgia. However, up to now, there has been no comparative study of these two plants on their efficacies and mechanisms, thus, further research is needed to evaluate their similarity and differ
PubMed: 34450164Seguridad y Precauciones
La seguridad del consumo de Murraya paniculata requiere una vigilancia estricta debido a su compleja composición química y la presencia de compuestos bioactivos. En mujeres embarazadas y lactantes, el uso debe evitarse de forma absoluta; el metilsalicilato presente en la planta actúa como un derivado del ácido salicílico, lo que puede provocar alteraciones en la coagulación fetal y riesgos de cierre prematuro del conducto arterioso durante el desarrollo gestacional. En la lactancia, la transferencia de alcaloides y terpenos a través de la leche materna carece de perfiles de seguridad establecidos en humanos, lo que impide su recomendación. En la población pediátrica, específicamente en niños menores de 12 años, existe un riesgo clínico de síndrome de Reye, debido a la toxicidad de los salicilatos que puede afectar el metabolismo mitocondrial y causar daño hepático y cerebral. En cuanto a las interacciones farmacológicas, la administración de la planta junto con warfarina incrementa significativamente el riesgo de hemorragias, ya que el metilsalicilato posee propiedades antiagregantes que potencian el efecto anticoagulante de la warfarina. La interacción con la metformina es preocupante, pues los alcaloides y saponinas pueden alterar la permeabilidad de las membranas intestinales, afectando la absorción de fármacos y la estabilidad glucémica.
Otras plantas estudiadas para Actividad analgésica
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