Nelumbo para Inflamación sistémica
Nelumbo nucifera — 9 estudios científicos revisados
Moderate¿Sirve Nelumbo para inflamación sistémica?
Sus propiedades antiinflamatorias actúan mediante la modulación de mediadores químicos que regulan la respuesta inflamatoria del cuerpo.
Compuestos activos involucrados: Alcaloides, Flavonoides, Saponinas, Terpenos, Fenoles, Glucósidos, Terpenoides, Compuestos fenólicos
Evidencia Científica
Los siguientes estudios han investigado la relación entre Nelumbo y inflamación sistémica:
Modifications of native lotus (Nelumbo nucifera G.) rhizome starch and its overall characterization: A review.
Lotus (Nelumbo nucifera G.) rhizomes are an under-utilized and sustainable starch source that constitutes up to 20 % starch. The review mainly focused on the extraction methods of starch, the chemical composition of LRS, and techno-functional characteristics such as swelling power, solubility, in vitro digestibility, pasting property, and gelatinization is highlighted in LRS review. Lotus rhizome starch (LRS) is also used as a water retention agent, thickening, gelling, stabilizing, and filling in food and non-food applications. Native starch has limited functional characteristics in food appl
PubMed: 37866555The Cytoprotective and Anti-cancer Potential of Bisbenzylisoquinoline Alkaloids from
Natural product therapy has been gaining therapeutic importance against various diseases, including cancer. The failure of chemotherapy due to its associated adverse effects promoted adjunct therapy with natural products. Phytochemicals exert anti-carcinogenic activities through the regulation of various cell signaling pathways such as cell survival, inflammation, apoptosis, autophagy and metastasis. The 'small molecule-chemosensitizing agents' from plants induce apoptosis in drug-resistant and host-immune resistant cancer cells in in vitro as well as in vivo models. For example, alkaloids fro
PubMed: 31738137An Updated Review on Nelumbo Nucifera Gaertn: Chemical Composition, Nutritional Value and Pharmacological Activities.
Nelumbo nucifera Gaertn is a recognised herbal plant in ancient medical sciences. Each portion of the plant leaf, flower, seed and rhizome is utilised for nutritional and medicinal purposes. The chemical compositions like phenol, alkaloids, glycoside, terpenoids and steroids have been isolated. The plant contains various nutritional values like lipids, proteins, amino acids, minerals, carbohydrates, and fatty acids. Traditional medicine confirms that the phytochemicals of plants give significant benefits to the treatment of various diseases such as leukoderma, smallpox, dysentery, haematemesis
PubMed: 38327030Nelumbo nucifera leaves extract ameliorated scopolamine-induced cognition impairment via enhanced adult hippocampus neurogenesis.
In this presentation, we explored the molecular mechanisms of N. nucifera leaf water extracts (NLWEs) and polyphenol extract (NLPE) on scopolamine-induced cell apoptosis and cognition defects. The administration of NLWE and NLPE did not alter the body weight and serum biomarker rs and significantly ameliorated scopolamine-induced cognition impairment according to Y-maze test analysis. In mice, treatment with scopolamine disrupted normal histoarchitecture in the hippocampus, whereas the administration of NLWE and NLPE reversed the phenomenon. Western blot analysis revealed that scopolamine miti
PubMed: 38351887Advances in the pharmacological effects and mechanisms of Nelumbo nucifera gaertn. Extract nuciferine.
ETHNOPHARMACOLOGIC RELEVANCE: The leaves of Nelumbo nucifera Gaertn. Are recorded in the earliest written documentation of traditional Chinese medicinal as "Ben Cao Gang Mu", a medicinal herb for blood clotting, dysentery and dizziness. Nuciferine, one of N. nucifera Gaertn. leaf extracts, has been shown to possess several pharmacological properties, including but not limited to ameliorating hyperlipidemia, stimulating insulin secretion, inducing vasodilation, reducing blood pressure, and demonstrating anti-arrhythmic properties.
PubMed: 38670406Seguridad y Precauciones
En lo que respecta al periodo de gestación y la etapa de lactancia materna, no existe evidencia científica suficiente en los estudios proporcionados para establecer un perfil de seguridad concluyente sobre el consumo de Nelumbo nucifera. Debido a la presencia de alcaloides y otros compuestos bioactivos que podrían atravesar la barrera placentaria o segregarse en la leche materna, se recomienda evitar su uso terapéutico durante estas etapas. La falta de estudios clínicos controlados en humanos sobre el impacto del loto en el desarrollo fetal o neonatal obliga a mantener una postura de precaución extrema para prevenir cualquier riesgo de teratogenicidad o alteraciones en el desarrollo del lactante. Para niños menores de 12 años, la seguridad no ha sido establecida. El sistema metabólico y los órganos en desarrollo de los infantes son más sensibles a los compuestos químicos como los terpenoides y esteroides presentes en la planta. El uso de extractos concentrados en esta población debe evitarse estrictamente hasta que existan datos farmacológicos que garanticen la ausencia de toxicidad aguda o crónica.
Otras plantas estudiadas para Inflamación sistémica
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