Frijol para Diabetes tipo 2
Phaseolus vulgaris — 5 estudios científicos revisados
Las vainas de phaseolus vulgaris son utilizadas en la fitoterapia latinoamericana y europea como coadyuvante en el control de la glucemia postprandial.¿Sirve Frijol para diabetes tipo 2?
Las faseolaminas presentes en las semillas inhiben la alfa-amilasa pancreática, retardando la digestión de almidones y reduciendo los picos de glucosa sanguínea tras las comidas.
Compuestos activos involucrados: Antocianinas, Flavonoides, Péptido, ácido, Alcaloides, Antocianina, Lípido, Frijol, Compuestos fenólicos, ácidos grasos
Evidencia Científica
Los siguientes estudios han investigado la relación entre Frijol y diabetes tipo 2:
Phaseolus vulgaris lectins: A systematic review of characteristics and health implications.
Legume lectins are carbohydrate-binding proteins of non-immune origin. Significant amounts of lectins have been found in Phaseolus vulgaris beans as far back as in the last century; however, many questions about their potential biological roles still remain obscure. Studies have shown that lectins are anti-nutritional factors that can cause intestinal disorders. Owing to their ability to act as toxic allergens and hemagglutinins, the Phaseolus vulgaris lectins are of grave concern for human health and safety. Nonetheless, their potential beneficial health effects, such as anti-cancer, anti-hum
PubMed: 26479307Common bean (Phaseolus vulgaris L.) α-amylase inhibitors as safe nutraceutical strategy against diabetes and obesity: An update review.
Overweight and obesity are constantly increasing, not only in Western countries but also in low-middle-income ones. The decrease of both the intake of carbohydrates and their assimilation are among the main dietary strategies to counter these conditions. α-Amylase, a key enzyme involved in the digestion of carbohydrates, is the target enzyme to reduce the absorption rate of carbohydrates. α-Amylase inhibitors (α-AIs) can be found in plants. The common bean, Phaseolus vulgaris is of particular interest due to the presence of protein-based α-AIs which, through a protein-protein interaction, redu
PubMed: 35485365The nutraceutical role of the Phaseolus vulgaris alpha-amylase inhibitor.
The present review assesses the potential of the Phaseolus vulgaris alpha-amylase inhibitor isoform 1 (alpha-AI1) starch blockers as a widely used remedy against obesity and diabetes. Consumption of the alpha-amylase inhibitor causes marginal intraluminal alpha-amylase activity facilitated by the inhibitor's appropriate structural, physico-chemical and functional properties. As a result there is decreased postprandial plasma hyperglycaemia and insulin levels, increased resistance of starch to digestion and increased activity of colorectal bacteria. The efficacy and safety of the amylase inhibi
PubMed: 18331662Glycaemic index of conventional carbohydrate meals.
The glycaemic index (GI) and the triacylglycerol response were measured in thirty non-insulin-dependent diabetes mellitus patients given 50 g portions of five different conventional Indian meals containing semolina (Triticum aestivum) cooked by two different methods, or combinations of semolina and pulse (black gram dhal (Phaseolus mungo), green gram dhal (Phaseolus aureus) or Bengal gram dhal (Cicer arietum)). There were no significant differences among meals in mean GI except for meals based on roasted semolina or semolina-black gram dhal. Compared with the blood glucose response for a 50 g
PubMed: 1445824Effects of some anti-diabetic herbal extracts on the insulin-degrading enzyme in human colon cancer Caco-2 cell line.
OBJECTIVE: Type 2 diabetes mellitus (T2DM) is a condition characterized by insufficient insulin production or insulin resistance. The insulin-degrading enzyme (IDE) is responsible for degrading insulin and is a potential drug target for T2DM treatment. Numerous activities have been proposed for plant extracts, but research on the effects of plant extracts on IDE expression and activity is riddled with drawbacks. MATERIALS AND METHODS: We investigated the effect of RESULTS: Findings of RT-PCR showed that IDE gene expression was reduced following treatment with CONCLUSION: The hydroalcoholic e
PubMed: 36249459Seguridad y Precauciones
La seguridad en el consumo de Phaseolus vulgaris debe abordarse desde una perspectiva integral, considerando que sus compuestos bioactivos, como las antocianinas y péptidos, poseen una alta actividad biológica. En el caso de mujeres embarazadas y en periodo de lactancia, no existen estudios clínicos que determinen una dosis segura de extractos concentrados; sin embargo, el consumo de la legumbre entera como alimento es generalmente seguro y nutritivo. Se debe evitar el consumo de extractos purificados de antocianinas o fracciones proteicas aisladas durante estas etapas debido a la falta de evidencia sobre su impacto en el desarrollo fetal o la transferencia de metabolitos a través de la leche materna. Para niños menores de 12 años, el frijol es una fuente esencial de proteínas y minerales, pero se debe prestar atención a la digestibilidad; el consumo excesivo de granos sin una cocción adecuada puede provocar malestar gastrointestinal debido a oligosacáridos fermentables. Respecto a las interacciones farmacológicas, es crítico considerar que los extractos de Phaseolus vulgaris pueden presentar efectos antiagregantes plaquetarios (inhibición de la agregación mediada por nitración de ácidos grasos, PMID [PMID 41683465]), lo que podría potenciar el riesgo de hemorragia si se combinan con fármacos anticoagulantes como la warfarina o antiagregantes como el ácido acetilsalicílico. Asimismo, debido a su potencial efecto reductor de la uricemia (PMID [PMID 41462435]), podría interferir con mecanismos de excreción renal o metabolismo de purinas.
Otras plantas estudiadas para Diabetes tipo 2
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