Phyllanthus para Tos y afecciones respiratorias
Phyllanthus amarus — 3 estudios científicos revisados
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Uso documentado en la medicina tradicional y respaldado por investigación preliminar
Compuestos activos involucrados: Alcaloides, Astragalina, Corilagina, Filantina, Flavonoides, Geraniina, Kaempferol, Lignanos, Lupeol, Quercetina, Rutina, Saponinas, Taninos, Terpenos, ácido elágico, ácido gálico, ácido oleanólico, ácido ursólico
Evidencia Científica
Los siguientes estudios han investigado la relación entre Phyllanthus y tos y afecciones respiratorias:
Schistosoma mansoni: In vivo evaluation of Phyllanthus amarus hexanic and ethanolic extracts.
Human schistosomiasis is an important neglected tropical disease caused by blood flukes of the genus Schistosoma and is responsible for more than 280,000 deaths annually. Treatment for this disease relies currently on a single drug, praziquantel (PZQ). Concerns regarding PZQ resistance and insensitivity of juvenile schistosomes have increased the interest in resorting to medicinal plants for alternative drug therapies. This study aimed to perform an in vivo schistosomicidal activity evaluation of crude hexanic (HE) and ethanolic (EE) extracts obtained from Phyllanthus amarus in mice infected w
PubMed: 29074138Preliminary phytochemical investigation and antibacterial activity of Phyllanthus amarus Schum & Thorn.
The aqueous extract of Phyllanthus amarus Schum & Thorn, was selected for preliminary phytochemical and antibacterial activity against human pathogens. Minimum inhibitory concentration was performed by broth dilution method and the zone of inhibition was studied by agar disc diffusion method at concentrations of 10 and 20 mg/ml in DMSO (Dimethyl Sulfoxide). The results revealed the antimicrobial activity of extract against the the strains of microorganisms concentrations in ranges of 60 and 500 μg/ml. Aqueous extract of leaves and roots of Phyllanthus amarus exhibited significant antibacterial
PubMed: 22557251Inhibitory effects of Phyllanthus amarus and its major lignans on human microsomal cytochrome P450 activities: evidence for CYP3A4 mechanism-based inhibition.
Phyllanthus amarus has long been used as a herbal medicine in several countries. Phytochemicals in herbal medicine may interact with cytochromes P450 (CYP) and thus raise the potential of herb-drug interactions; therefore, the inhibitory effects of P. amarus and its major phytochemicals phyllanthin and hypophyllanthin on CYP isoforms were determined using human liver microsomes and selective substrates. Both ethanolic and aqueous extracts of P. amarus inhibited CYP1A2, CYP2D6, CYP2E1 and CYP3A4 in a dose-dependent manner.
PubMed: 21178301Contexto Científico
Se descubrió que compuestos como la filantina y la quercetina pueden alterar redes de señalización celular como NF-κB, MAPKs y PI3K/Akt. El significado es que la planta podría actuar regulando estos interruptores para prevenir procesos de proliferación celular descontrolada (cáncer) o inflamación crónica. La transición de los resultados de laboratorio a la práctica clínica requiere estudios humanos rigurosos para validar estos hallazgos.
Seguridad y Precauciones
Consulte a un profesional de salud antes de utilizar Phyllanthus para tos y afecciones respiratorias. La información presentada es de carácter educativo y no sustituye el consejo médico profesional.
Otras plantas estudiadas para Tos y afecciones respiratorias
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