Vicia para Anemia hemolítica (Favismo)

Vicia faba — 5 estudios científicos revisados

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¿Sirve Vicia para anemia hemolítica (favismo)?

En individuos con deficiencia de la enzima G6PD, el consumo de faba beans puede provocar la oxidación de la hemoglobina, resultando en la ruptura de los glóbulos rojos (hemólisis).

Compuestos activos involucrados: Flavonoides, Legumina, Prolina, Vicilina, Compuestos fenólicos

Evidencia Científica

Los siguientes estudios han investigado la relación entre Vicia y anemia hemolítica (favismo):

Genetic diversity and relationship of global faba bean (Vicia faba L.) germplasm revealed by ISSR markers.

Genetic diversity and relationships of 802 faba bean (Vicia faba L.) landraces and varieties from different geographical locations of China and abroad were examined using ISSR markers. A total of 212 repeatable amplified bands were generated with 11 ISSR primers, of which 209 were polymorphic. Accessions from North China showed highest genetic diversity, while accessions from central China showed low level of diversity. Chinese spring faba bean germplasm was clearly separated from Chinese winter faba bean, based on principal component analysis and UPGMA clustering analysis. Winter accessions f

PubMed: 22204023

Effects of faba bean (Vicia faba L.) on fillet quality of Yellow River carp (Cyprinus carpio) via the oxidative stress response.

In order to further explain the fillet texture improvement of Yellow River carp (Cyprinus carpio) fed with faba bean (Vicia faba L.), a three-month rearing trial was conducted to investigate fatty acid composition, antioxidant capacity, myofiber development, collagen deposition and transcriptome in white muscle of two farmed carp groups (One was fed only faba bean, the other was fed commercial diet). As a strong oxidant, faba bean changed fatty acids composition in white muscle, especially DHA and EPA, up-regulated the levels of reactive oxygen species (ROS) and down-regulated major antioxidan

PubMed: 35483280

Improvement of Vicia faba plant tolerance under salinity stress by the application of thiamine and pyridoxine vitamins.

Enhancement of plant growth at early growth stages is usually associated with the stimulation of various metabolic activities, which is reflected on morphological features and yield quantity and quality. Vitamins is considered as anatural plant metabolites which makes it a safe and ecofriendly treatment when used in appropriate doses, for that this research aimed to study the effect of two different vitamin B forms (thiamine and pyridoxine) on Vicia faba plants as agrowth stimutator in addition to study it's effect on plant as astrong antioxidant under salinity stress.Our findings demonstrated

PubMed: 39333671

Exploring the anticancer and antioxidant properties of

BACKGROUND: Pulse crops are considered the major sources of proteins, dietary fiber, micronutrients, and bioactive phytochemicals. Among the numerous pulse crops, broad beans ( METHODS: In order to investigate the VFs properties, the flours from broad beans of three different harvest periods were extracted with acetone, methanol and 70% aqueous ethanol and the dried extracts were analyzed, qualitatively and quantitatively, and tested for their antioxidant through DPPH and ABTS assay and anticancer activities using the MTT assay and immunofluorescence analysis. RESULTS: The VF extracts demonstr

PubMed: 35996664

In vitro and in silico analyses of Vicia faba L. on Peroxisome proliferator-activated receptor gamma.

The agonists of peroxisome proliferator-activated receptor gamma (PPARγ) from natural victual products were used as antidiabetic agents. Faba bean (Vicia faba L.) is a consequential legume that was known to possess potential antidiabetic activity, whose mechanism of action was unknown. The current study was focused to ascertain gene expression of the nuclear receptor PPARγ by Faba bean pod extract in rat cell lines (RINm5F).The real-time polymerase chain reaction analysis demonstrated that Faba bean pod extract in concentrations of 160 µg/mL have shown 4.97-fold stimulation compared with contr

PubMed: 29923224

Seguridad y Precauciones

La seguridad en el consumo de Vicia faba (haba) es un tema de vital importancia debido a la presencia de compuestos antinutricionales y factores genéticos específicos. En primer lugar, respecto al embarazo y la lactancia, no existen estudios clínicos exhaustivos en humanos que establezcan una dosis segura o riesgos directos; sin embargo, se debe proceder con extrema cautela. El consumo excesivo de leguminosas puede interferir con la absorción de ciertos micronutrientes esenciales para el desarrollo fetal. Además, el riesgo de favismo (una condición hemolítica) es una preocupación latente si la madre o el lactante poseen una deficiencia de la enzima glucosa-6-fosfato deshidrogenasa (G6PD). En el caso de la lactancia, aunque los componentes proteicos suelen ser seguros, cualquier alteración en la composición de la dieta materna podría afectar indirectamente al lactante a través de la leche. Para niños menores de 12 años, la precaucción debe ser mayor debido a que sus sistemas enzimáticos y metabólicos están en desarrollo.

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