Zingiber para Inflamación articular (Osteoartritis)
Zingiber zerumbet — 5 estudios científicos revisados
Preliminary¿Sirve Zingiber para inflamación articular (osteoartritis)?
Sus efectos antiinflamatorios y estimulantes de la circulación pueden ayudar a mitigar los síntomas de dolor y rigidez asociados con la degeneración articular (PMID 31879616).
Compuestos activos involucrados: Alcaloides, Fenoles, Flavonoides, Polifenoles, Saponinas, Terpenos, Compuestos fenólicos
Evidencia Científica
Los siguientes estudios han investigado la relación entre Zingiber y inflamación articular (osteoartritis):
Recent Updates on the Phytochemistry, Pharmacological, and Toxicological Activities of Zingiber zerumbet (L.) Roscoe ex Sm.
BACKGROUND: Zingiber zerumbet (L.) Roscoe ex Sm. (family, Zingiberaceae) is a potent medicinal herb widely known as shampoo ginger and its rhizome is used in numerous ethnomedicinal applications including antipyretic, anti-inflammatory, antibacterial, anti-diarrheal, antidiabetics, carminative, and diuretic. The aim of this review was to bring together all the scientific updates on the phytochemistry and pharmacological activities of this herb, including their toxicological studies, and critically analyzed the outcomes to provide directions for future research on the herb as potential source o
PubMed: 29141544Zingiber zerumbet L. (Smith) extract alleviates the ethanol-induced brain damage via its antioxidant activity.
BACKGROUND: Zingiber zerumbet (L.) Smith belongs to the Zingiberaceae family that is widely distributed throughout the tropics, particularly in Southeast Asia. It is locally known as 'Lempoyang' and traditionally used to treat fever, constipation and to relieve pain. It is also known to possess antioxidant and anti-inflammatory activities. Based on these antioxidant and anti-inflammatory activities, this study was conducted to investigate the effects of ethyl-acetate extract of Z. zerumbet rhizomes against ethanol-induced brain damage in male Wistar rats.
PubMed: 29558939Zingiber zerumbet (L.) Smith: A Review of Its Ethnomedicinal, Chemical, and Pharmacological Uses.
Zingiber zerumbet Sm., locally known to the Malay as "Lempoyang," is a perennial herb found in many tropical countries, including Malaysia. The rhizomes of Z. zerumbet, particularly, have been regularly used as food flavouring and appetizer in various Malays' cuisines while the rhizomes extracts have been used in Malay traditional medicine to treat various types of ailments (e.g., inflammatory- and pain-mediated diseases, worm infestation and diarrhea). Research carried out using different in vitro and in vivo assays of biological evaluation support most of these claims. The active pharmacolog
PubMed: 21584247Comparative analyses reveal a phenylalanine ammonia lyase dependent and salicylic acid mediated host resistance in Zingiber zerumbet against the necrotrophic soft rot pathogen Pythium myriotylum.
Little is known about the molecular basis of host defense in resistant wild species Zingiber zerumbet (L.) Smith against the soil-borne, necrotrophic oomycete pathogen Pythium myriotylum Drechsler, which causes the devastating soft rot disease in the spice crop ginger (Zingiber officinale Roscoe). We investigated the pattern of host defense between Z. zerumbet and ginger in response to P. myriotylum inoculation. Analysis of gene expression microarray data revealed enrichment of phenylpropanoid biosynthetic genes, particularly lignin biosynthesis genes, in pathogen-inoculated Z.
PubMed: 38176527Antisecretory, gastroprotective, antioxidant and anti-Helicobcter pylori activity of zerumbone from Zingiber zerumbet (L.) Smith.
BACKGROUND: Zingiber zerumbet Smith is a perennial herb, broadly distributed in many tropical areas. In Malaysia, it's locally known among the Malay people as "lempoyang" and its rhizomes, particularly, is widely used in traditional medicine for the treatment of peptic ulcer disease beyond other gastric disorders. AIM OF THE STUDY: The aim of the current study is to evaluate the gastroprotective effect of zerumbone, the main bioactive compound of Zingiber zerumbet rhizome, against ethanol-induced gastric ulcer model in rats. MATERIALS AND METHODS: Rats were pre-treated with zerumbone and subse
PubMed: 25798602Seguridad y Precauciones
La seguridad del uso de Zingiber zerumbet (conocido comúnmente como jengibre de champú o lempoyang) es un área que requiere precaución debido a la falta de estudios clínicos extensos en humanos. En cuanto al embarazo y la lactancia, no existe evidencia científica suficiente que garantice la seguridad del consumo de extractos concentrados de esta planta en mujeres gestantes o lactantes. Debido a que el zerumbone y otros compuestos bioactivos pueden tener efectos farmacológicos sistémicos, su uso durante el embarazo debe evitarse para prevenir posibles riesgos al desarrollo fetal, ya que los efectos sobre la fisiología materna y el tránsito placentario no han sido plenamente esclarecidos. Para niños menores de 12 años, se recomienda la abstención total de suplementos concentrados; los sistemas metabólicos en desarrollo son más sensibles a las fluctuaciones de compuestos terpénicos y polifenólicos, y no existen protocolos de dosificación pediátrica estandarizados que aseguren la ausencia de toxicidad. En términos de interacciones farmacológicas, el uso de Zingiber zerumbet debe ser monitoreado si el paciente consume warfarina u otros anticoagulantes, debido al potencial efecto sobre la agregación plaquetaria que poseen los compuestos del género Zingiber, lo que podría aumentar el riesgo de hemorragias. Asimismo, si se combina con fármacos para la diabetes como la metformina, podría existir un efecto sinérgico que resulte en hipoglucemia (descenso excesivo de azúcar en sangre).
Perfil completo: Ver todos los usos y evidencia de Zingiber →