Allium para Nefropatía diabética
Allium tuberosum — 4 estudios científicos revisados
Moderate¿Sirve Allium para nefropatía diabética?
Ayuda a mitigar el daño renal causado por la diabetes al suprimir el estrés oxidativo y la inflamación en los tejidos renales (PMID 30784905).
Compuestos activos involucrados: Flavonoides, Saponinas, Terpenos, Alicina, Glucósidos, Isopreno
Evidencia Científica
Los siguientes estudios han investigado la relación entre Allium y nefropatía diabética:
Allium tuberosum: Antidiabetic and hepatoprotective activities.
Allium tuberosum (AT) is traditionally used for treating nocturnal emissions, abdominal pain, diarrhea, sexual dysfunction and asthma. This study aimed at investigating the antidiabetic and hepatoprotective activities of the butyl alcohol fraction from the methanolic extract of A. tuberosum. For the antidiabetic activity, rats were induced with diabetes by intraperitoneal injection of 150mg/kg alloxan and treated for 30days with AT extract (100, 200 and 400mg/kg). Animals were sacrificed after the study and the fasting blood glucose (FBG), triglyceride (TG), total cholesterol (TC), HDL, malond
PubMed: 29196001Allium tuberosum alleviates diabetic nephropathy by supressing hyperglycemia-induced oxidative stress and inflammation in high fat diet/streptozotocin treated rats.
The objective of this study was to evaluate the effect of the butanol fraction from Allium tuberosum (BFAT) in high fat diet/streptozotocin (HFD/STZ) induced diabetic nephropathy. Wistar rats were fed with HFD for 4 weeks and thereafter administered with 35 mg/kg STZ intraperitoneally. Diabetic rats were treated with BFAT (100 or 400 mg/kg) and metformin (150 mg/kg) for 40 days. After treatment, the blood, urine and kidney tissues were obtained for biochemical and histological analysis. BFAT markedly decreased blood glucose, serum creatinine, blood urea nitrogen and urinary albumin levels in d
PubMed: 30784905Biochar reduced Chinese chive (Allium tuberosum) uptake and dissipation of thiamethoxam in an agricultural soil.
Information about the effect of biochar on the environmental fate of pesticide thiamethoxam (THI) in soil-vegetable ecosystems is limited. Therefore, the influence of a wood-derived biochar produced at 450 °C (BC450) on the uptake of THI by Chinese chive (Allium tuberosum) and its dissipation in soil was investigated using a 42-day pot experiment. BC450 addition decreased THI uptake and its metabolite clothianidin (CLO) by 22.8 % and 37.6 %, respectively. However, the half-life of THI in soil rose from 89.4-120 days, indicating that BC450 increased soil THI's persistence. The decreased bioavai
PubMed: 31818655Research and application of leek roots in medicinal field.
Some Chinese herbs have been used to prevent and treat diseases, and are also used as common food ingredients. These Chinese herbs are potential resource for research and development of new drugs. Leek roots is a typical medicine of food and medicine continuum. It has a long history of medicinal applications and edible food in China. In this paper, the origin, biological active components, pharmacological action and clinical application of leek roots were introduced.
PubMed: 37538865Seguridad y Precauciones
La seguridad del consumo de Allium tuberosum (ajo chino) debe abordarse con cautela, especialmente cuando se transiciona de un uso culinario a uno terapéutico. En el contexto de embarazo y lactancia, no existe evidencia clínica suficiente en humanos que garantice la seguridad del consumo de extractos concentrados; por lo tanto, se recomienda evitar dosis terapéuticas elevadas, ya que los compuestos bioactivos podrían atravesar la barrera placentaria o excretarse en la leche materna, con efectos potencialmente desconocidos en el desarrollo fetal o neonatal. Para niños menores de 12 años, el uso de extractos de Allium tuberosum no está indicado debido a la falta de estudios de seguridad pediátrica y al riesgo de irritación gastrointestinal o alteraciones en la coagulación. Respecto a las interacciones farmacológicas, el mecanismo de acción del Allium tuberosum sobre el metabolismo de la glucosa (como se sugiere en PMID 29196001 y PMID 30784905) puede potenciar el efecto de fármacos antidiabéticos como la metformina, aumentando el riesgo de hipoglucemia. Asimismo, debido a sus propiedades que afectan la homeostasis sanguínea, podría interactuar con la warfarina y otros anticoagulantes, incrementando el riesgo de hemorragias. También es necesario vigilar la interacción con antihipertensivos, ya que cambios en la presión arterial podrían ocurrir de forma sinérgica.
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