Anacardium para Anafilaxia (Reacción alérgica sistémica)
Anacardium corymbosum — 10 estudios científicos revisados
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La sensibilización previa mediante IgE provoca la degranulación de mastocitos y basófilos al entrar en contacto con las proteínas del fruto, liberando mediadores como el PAF (factor activador de plaquetas) que causa colapso circulatorio.
Compuestos activos involucrados: Saponinas, Terpenos, Ácido gálico
Evidencia Científica
Los siguientes estudios han investigado la relación entre Anacardium y anafilaxia (reacción alérgica sistémica):
Emerging roles of anacardic acid and its derivatives: a pharmacological overview.
Anacardic acid (AA) is a bioactive phytochemical found in nutshell of Anacardium occidentale. Chemically, it is a mixture of several closely related organic compounds, each consisting of salicylic acid substituted with an alkyl chain. The traditional Ayurveda depicts nutshell oil as a medicinal remedy for alexeritic, amebicidal, gingivitis, malaria and syphilitic ulcers. However, the enduring research and emerging evidence suggests that AA could be a potent target molecule with bactericide, fungicide, insecticide, anti-termite and molluscicide properties and as a therapeutic agent in the treat
PubMed: 22103711Review on medicinal plants and natural compounds as anti-Onchocerca agents.
Onchocerciasis is a filarial vector borne disease which affects several million people mostly in Africa. The therapeutic approach of its control was based on a succession of drugs which always showed limits. The last one: ivermectin is not the least. It was shown to be only microfilaricidal and induced resistance to the human parasite Onchocerca volvulus. The approach using medicinal plants used in traditional medicine is a possible alternative method to cure onchocerciasis.
PubMed: 30008135Medicinal plants used for dogs in Trinidad and Tobago.
This paper documents ethnoveterinary medicines used to treat dogs in Trinidad and Tobago. In 1995, a 4-stage process was used to conduct the research and document the ethnoveterinary practices. Twenty-eight ethnoveterinary respondents were identified using the school-essay method, which is a modified rapid rural appraisal (RRA) technique. Semi-structured interviews were held with these respondents as well as with 30 veterinarians, 27 extension officers and 19 animal-health assistants and/or agricultural officers, and the seven key respondents that they identified. The final step involved hosti
PubMed: 10821961Botanical treatments for snakebite in rural Ghana: A narrative review.
ETHNOPHARMACOLOGICAL RELEVANCE: In the countryside, there are some limitations with the use of venom antisera to manage snake bites. Due to poor access to healthcare and as a result of the difficulty in receiving treatment for cases of snake bites, most rural people in Ghana, a West African country, rely on plant medicine as a first aid to manage cases of venomous snakebite. This calls for more research into the species of plants used to medically manage snakebite envenomation. AIM OF THE STUDY: This review sought to present plants that are used in managing snakebite cases and also gather data
PubMed: 34274442Gallic acid anti-myotoxic activity and mechanism of action, a snake venom phospholipase A
Snakebite envenoming is the cause of an ongoing health crisis in several regions of the world, particularly in tropical and neotropical countries. This scenario creates an urgent necessity for new practical solutions to address the limitations of current therapies. The current study investigated the isolation, phytochemical characterization, and myotoxicity inhibition mechanism of gallic acid (GA), a myotoxin inhibitor obtained from Anacardium humile. The identification and isolation of GA was achieved by employing analytical chromatographic separation, which exhibited a compound with retentio
PubMed: 34197854Seguridad y Precauciones
La seguridad en el uso de Anacardium (específicamente Anacardium occidentale/corymbosum) es un tema de alta complejidad debido a su potencial alergénico sistémico. En el contexto de embarazo y lactancia, no existen estudios clínicos que determinen la seguridad del consumo de productos derivados de la corteza o frutos en mujeres gestantes; sin embargo, debido al riesgo de reacciones alérgicas agudas (anafilaxia) que podrían comprometer el flujo sanguíneo materno o causar estrés fetal, se recomienda evitar su uso medicinal. En la lactancia, aunque los componentes pueden pasar a la leche materna, la principal preocupación es la posibilidad de que el lactante presente una sensibilidad cruzada o reacciones alérgicas mediadas por IgE tras la ingesta indirecta. Para niños menores de 12 años, el riesgo es significativamente mayor. La evidencia clínica (PMID 38880088) indica una altísima tasa de sensibilidad cruzada entre el marañón (cashew), el pistacho y el terebinto; en niños con sensibilidad previa a frutos secos, la ingesta accidental puede desencadenar anafilaxia, una emergencia médica que requiere epinefrina. En cuanto a interacciones farmacológicas, no se han documentado interacciones directas con metformina o antihipertensivos en la literatura proporcionada, pero se debe considerar que cualquier sustancia con actividad biológica puede alterar el metabolismo hepático.
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