Yopo para Estrés oxidativo
Anadenanthera peregrina — 13 estudios científicos revisados
Preliminary¿Sirve Yopo para estrés oxidativo?
Peregrina identificó compuestos fenólicos con actividad antioxidante significativa (DPPH IC50 de 12.
Compuestos activos involucrados: Alcaloides, Bufotenina, Dimetiltriptamina, Flavonoides, Saponinas, Terpenos, Glucósido, Glucósidos, Serotonina, Compuestos fenólicos
Evidencia Científica
Los siguientes estudios han investigado la relación entre Yopo y estrés oxidativo:
Anti-inflammatory effect of Anadenanthera colubrina var. cebil (Griseb.) Altschul in experimental elastase-induced pulmonary emphysema in rats.
ETHNOPHARMACOLOGICAL RELEVANCE: Medicinal plants have shown promise in the search for new treatments of pulmonary emphysema. Anadenanthera colubrina, a species native to the Caatinga biome in northeastern Brazil, is widely recognized and traditionally employed in the treatment of pulmonary diseases. Many studies corroborate popular knowledge about the medicinal applications of A. colubrina, which has demonstrated a remarkable variety of pharmacological properties, however, its anti-inflammatory and antioxidant properties are highlighted. AIM OF THE STUDY: The objective of this study was to inv
PubMed: 38642622Bark anatomy, chemical composition and ethanol-water extract composition of Anadenanthera peregrina and Anadenanthera colubrina.
The bark of Anadenanthera peregrina (L.) Speg and Anadenanthera colubrina (Vell.) Brenan were characterized in relation to anatomical and chemical features. The barks were similar and included a thin conducting phloem, a largely dilated and sclerified non-conducting phloem, and a rhyridome with periderms with thin phellem interspersed by cortical tissues. Only small differences between species were observed that cannot be used alone for taxonomic purposes. The summative chemical composition of A. peregrina and A.
PubMed: 29281656Bio-based phenolic foams from Anadenanthera peregrina tannins: Synthesis, structure and performance.
Tannin-based foams are natural-origin porous materials that offer promising alternatives to flammable synthetic foams due to their fire resistance and thermal insulation properties; however, their brittleness and relatively low mechanical resistance present challenges, necessitating improvements to these properties. This work aimed to investigate four types of tannin-based foams (ST, TT, TB, and TTB) prepared without formaldehyde, by using Anadenanthera peregrina tannins (ST) and the incorporation of polysorbate Tween 80 as a surfactant (TT), bamboo fibers as filler reinforcement (TB), and the
PubMed: 40701477Phytochemical characterization, and antioxidant and antibacterial activities of the hydroethanolic extract of Anadenanthera peregrina stem bark.
The Brazilian Cerrado biome consists of a great variety of endemic species with several bioactive compounds, and Anadenanthera peregrina (L.) Speg is a promising species. In this study, we aimed to perform phytochemical characterization and evaluate the antioxidant and antibacterial activities against Staphylococcus aureus and Escherichia coli of the hydroethanolic extract of A. peregrina stem bark. The barks were collected in the Botanical Garden of Goiânia, Brazil. The hydroethanolic extract was obtained by percolation and subjected to physicochemical screening, total phenolic content estima
PubMed: 33681898Phosphorus improves arsenic phytoremediation by Anadenanthera peregrina by alleviating induced oxidative stress.
Due to similarities in their chemical behaviors, studies examining interactions between arsenic (As)--in special arsenate--and phosphorus (P) are important for better understanding arsenate uptake, toxicity, and accumulation in plants. We evaluated the effects of phosphate addition on plant biomass and on arsenate and phosphate uptake by Anadenanthera peregrina, an important Brazilian savanna legume. Plants were grown for 35 days in substrates that received combinations of 0, 10, 50, and 100 mg kg(-1) arsenate and 0, 200, and 400 mg kg(-1) phosphate. The addition of P increased the arsenic-phy
PubMed: 23819264Contexto Científico
En lenguaje simple, esto significa que el método de inhalación o uso de rapé permite que los efectos sean mucho más intensos y duraderos que si se ingirieran oralmente de forma aislada. Existe una comprensión clara de la presencia de bufotenina y la importancia de la inhibición de la MAO para su efecto, pero la investigación clínica rigurosa y controlada en entornos médicos modernos es limitada en comparación con la vasta evidencia etnobotánica y los estudios de farmacología experimental reportados. peregrina identificó compuestos fenólicos con actividad antioxidante significativa (DPPH ) y antibacteriana contra Staphylococcus aureus y Escherichia coli (PMID: 33681898). Extractos del género Anadenanthera demostraron actividad antiproliferativa in vitro contra líneas celulares tumorales, con selectividad hacia células cancerosas sobre células normales (PMID: 25093029).
Seguridad y Precauciones
El uso de Anadenanthera peregrina conlleva riesgos significativos debido a su alta concentración de alcaloides triptamínicos, principalmente la bufotenina (5-HO-DMT). En mujeres embarazadas o en periodo de lactancia, el consumo de yopo está estrictamente contraindicado. No existe evidencia clínica segura sobre el paso de la bufotenina a través de la barrera placentaria, pero la potencia de estos alcaloides podría inducir contracciones uterinas o alteraciones en el desarrollo fetal. En la lactancia, los componentes pueden excretarse en la leche materna, con riesgos potenciales de neurotoxicidad en el lactante. Para niños menores de 12 años, el uso es extremadamente peligroso; su sistema nervioso central está en desarrollo y la exposición a dosis de triptaminas puede alterar la neuroplasticidad y el desarrollo cognitivo de forma irreversible. En cuanto a interacciones farmacológicas, la administración de yopo junto con fármacos que actúan sobre el sistema serotoninérgico (como los inhibidores selectivos de la recaptación de serotonina, ISRS) puede desencadenar un síndrome serotoninérgico, una emergencia médica caracterizada por hipertermia, agitación y convulsiones.
Otras plantas estudiadas para Estrés oxidativo
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