Romerillo para Inflamación sistémica y localizada
Bidens pilosa — 10 estudios científicos revisados
Strong¿Sirve Romerillo para inflamación sistémica y localizada?
Reduce los niveles de citoquinas proinflamatorias como TNF-α, IL-6, IL-1β e IL-8, mitigando la respuesta inflamatoria celular.
Compuestos activos involucrados: Alcaloides, Flavonoides, Luteolina, Quercetina, Saponinas, Terpenos, Distribuido, Metabol, ácido, ácidos grasos
Evidencia Científica
Los siguientes estudios han investigado la relación entre Romerillo y inflamación sistémica y localizada:
Antioxidant Effects of Aqueous Bidens pilosa in Fructose-Fed Rats.
This narrative review synthesizes preclinical evidence on the antioxidant potential of simple water extracts from the aerial parts of Bidens pilosa in rodent models exposed to chronic fructose feeding. It examines study designs, aqueous extract preparation, and outcome measures, with emphasis on redox and inflammatory endpoints. Across reports, aqueous B. pilosa reduces lipid peroxidation, restores endogenous antioxidant defenses (superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), and reduced glutathione (GSH)), and improves histopathology in organs affected by diet-indu
PubMed: 41431509Phytotoxic Activity of Myrciaria cuspidata O. Berg, a Dominant Myrtaceae Woodland Tree Native of Brazil.
Limited phytodiversity and regeneration rates occur in some of the southern Brazilian formations known as the Myrtacean Woodlands. Data on phytotoxicity, chemical composition, and allelopathic potential of Myrciaria cuspidata O. Berg, a dominant species in such woodlands, is missing. In this study, both the chemical composition and phytotoxic activity of an aqueous extract (AE) from M. cuspidata leaves were investigated.
PubMed: 39683086Ethnomedicinal Evidence for Medicinal Plants of the Asteraceae Family Used by Tanzanians to Treat Various Ailments: A Review.
The Asteraceae family is amongst the most important groups of flowering plants, widely recognised for its ethnomedicinal relevance. This systematic review, conducted in line with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, synthesises evidence on the traditional medicinal uses of Asteraceae species in Tanzania. Data were compiled from multiple electronic databases, including but not limited to Web of Science, Scopus, Google Scholar, African Journals Online, PubMed and Wiley Online Library, and after rigorous screening, 31 studies from 16 regions
PubMed: 41925084Integrating network pharmacology and molecular modeling to decipher the anti-esophageal squamous cell carcinoma mechanisms of Bidens pilosa L.
UNLABELLED: Bidens pilosa L (BL), known for its anti-inflammatory, antioxidant, and anticancer properties across multiple malignancies, was investigated for its potential therapeutic effects against esophageal squamous cell carcinoma (ESCC). Through integrative network pharmacology and computational approaches, 10 bioactive compounds from BL were identified from HERB 2.0, symMap, BATMAN-TCM (target prediction score cutoff = 20, adjusted P-value = 0.05 for target analyses), TCMSP (oral bioavailability ≥ 30% and drug likeness ≥ 0.18), and ETCM 2.0 databases, while 3,993 ESCC-associated targets w
PubMed: 40836204Exploring the phytochemical profile, antioxidant and anti-inflammatory potential of Bidens pilosa: A Systematic Review.
Medicinal plants have garnered significant attention for their potential in treating various human diseases. Many of these plants exhibit antioxidant and anti-inflammatory properties, which are crucial for mitigating the impact of oxidative stress and inflammation implicated in numerous clinical conditions. This review investigated the antioxidant and anti-inflammatory properties of medicinal plants, particularly Bidens pilosa, and their potential applications in disease management. A structured systematic approach was employed for this analysis. Scopus, PubMed, and Web of Science were searche
PubMed: 40822453Seguridad y Precauciones
La seguridad en el uso de Bidens pilosa (Romerillo) es un área de estudio en desarrollo y requiere extrema precaución debido a la falta de ensayos clínicos robustos en humanos. En cuanto al embarazo y la lactancia, no existen estudios clínicos que garanticen la ausencia de efectos teratogénicos o alteraciones en la transferencia de compuestos bioactivos a través de la leche materna; por lo tanto, su uso está estrictamente contraindicado en mujeres gestantes y lactantes para evitar riesgos potenciales al desarrollo fetal o neonatal. En niños menores de 12 años, la seguridad no ha sido establecida, y la alta concentración de metabolitos como flavonoides y alcaloides podría interferir con procesos de desarrollo fisiológico en etapas críticas. Respecto a interacciones farmacológicas, se debe evitar su consumo concomitante con warfarina y otros anticoagulantes, dado que la presencia de compuestos como la quercetina y otros flavonoides podría alterar la cascada de coagulación y potenciar el riesgo de hemorragias. Con la metformina y otros antidiabéticos, existe un riesgo teórico de hipoglucemia por sinergia metabólica. Asimismo, su uso con fármacos antihipertensivos podría inducir fluctuaciones en la presión arterial debido a su actividad sobre mecanismos de señalización celular.
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