Chanca piedra para Diabetes y control glucémico
Phyllanthus niruri — 9 estudios científicos revisados
Moderate¿Sirve Chanca piedra para diabetes y control glucémico?
Tercero, en cuanto a la protección de órganos, la evidencia sugiere que la planta posee propiedades que podrían ayudar en la protección renal, especialmente en contextos de diabetes, aunque los...
Compuestos activos involucrados: filantina, hipofilantina, lignanos, flavonoides, Alcaloides, Conocido, Distribuido, Saponinas, Terpeno, Terpenos, Compuestos fenólicos
Evidencia Científica
Los siguientes estudios han investigado la relación entre Chanca piedra y diabetes y control glucémico:
Role of Phyllanthus niruri on the modulation of stress and immune responses in Nile tilapia, Oreochromis niloticus.
The use of nutraceuticals in aquaculture is getting attention to minimize oxidative stress and increase immunity of aquatic animals. In our experiment, we tested the potency of Phyllanthus niruri, as a stress-reducing and immune-stimulating agent in Nile tilapia, Oreochromis niloticus. We reared fish in a recirculating system for 90 days at low (5 g/L) and high (30 g/L) densities. We fed half of the low and high-density fish with commercial feed (control feed) and the other half, with 5% Phyllanthus niruri incorporated into commercial feed (supplemented feed). We assessed plasma cortisol, bloo
PubMed: 39418243Traditional uses, bioactive composition, pharmacology, and toxicology of Phyllanthus emblica fruits: A comprehensive review.
ETHNOPHARMACOLOGICAL RELEVANCE: The fruits of Phyllanthus emblica Linn or Emblica officinalis Gaertn (Phyllanthaceae), (FPE) commonly known as Indian gooseberry or Amla, gained immense importance in indigenous traditional medicinal systems, including Ayurveda, for its medicinal and nutritional benefits. It is used to cure several diseases such as common cold, fever, cough, asthma, bronchitis, diabetes, cephalalgia, ophthalmopathy, dyspepsia, colic, flatulence, hyperacidity, peptic ulcer, erysipelas, skin diseases, leprosy, hematogenesis, inflammation, anemia, emaciation, hepatopathy, jaundice,
PubMed: 34480995Phyllanthus niruri (stone breaker) herbal therapy for kidney stones; a systematic review and meta-analysis of clinical efficacy, and Google Trends analysis of public interest.
INTRODUCTION: Phyllanthus niruri (P. niruri) is the most commonly listed active ingredient in commercially available herbal therapies for kidney stones, despite limited supporting clinical evidence. We performed a meta-analysis to evaluate its efficacy in reducing stone burden. We used Google Trends to analyze its relative popularity in internet searches relative to conventional stone therapies. MATERIALS AND METHODS: A comprehensive literature search for controlled human studies containing data on the effect of P.
PubMed: 32333735Maternal-fetal repercussions of Phyllanthus niruri L. treatment during rat pregnancy.
ETHNOPHARMACOLOGICAL RELEVANCE: Phyllanthus niruri is a well-known plant for its therapeutic purposes to treat various diseases, being widely used by the population, mainly by women. However, there is no scientific confirmation of the effects of use during pregnancy. AIM OF THE STUDY: Evaluating the effect of Phyllanthus niruri aqueous extract on the maternal toxicity, reproductive outcomes and fetal anomaly incidence in rats. MATERIALS AND METHODS: Pregnant rats were distributed into four experimental groups: Control = treated with water (vehicle); Treated 150 = treated with P. niruri at dose
PubMed: 32145330Phyllanthus niruri versus Placebo for Chronic Hepatitis B Virus Infection: A Randomized Controlled Trial.
BACKGROUND: This study aimed to investigate the efficacy and safety of a 12-month treatment with Phyllanthus niruri in subjects with chronic hepatitis B virus (HBV) infection. PATIENTS AND METHODS: A placebo-controlled, parallel-group double-blind trial was performed. Clinical assessments took place at baseline and at 1, 3, 9, and 12 months after the treatment start and 6 months after treatment end. RESULTS: In the first 2 years, 50 eligible subjects with chronic HBV accepted to participate. Of those, 47 completed all the study-related visits (6% drop-out rate): 24 of the 26 (92%) allocated to
PubMed: 30372693Seguridad y Precauciones
El uso de Phyllanthus niruri, conocida tradicionalmente por los curanderos del norte de Perú para tratar diversas inflamaciones, requiere una precaución extrema debido a la falta de ensayos clínicos de fase III en humanos que establezcan perfiles de seguridad definitivos y dosis terapéuticas estandarizadas. En mujeres embarazadas y en periodo de lactancia, el consumo está estrictamente desaconsejado; la evidencia sobre el impacto de sus lignanos y flavonoides en el desarrollo fetal o en la composición de la leche materna es inexistente, lo que representa un riesgo potencial para el desarrollo del neonato que no puede ser ignorado. Para la población pediátrica, especialmente en niños menores de 12 años, el uso es altamente riesgoso, dado que sus sistemas metabólicos renales y hepáticos son aún inmaduros para procesar concentraciones de compuestos bioactivos como la filantina sin supervisión médica. Las interacciones farmacológicas son de alta relevancia clínica y deben ser monitoreadas. El uso concomitante con la warfarina puede potenciar el efecto anticoagulante, incrementando el riesgo de hemorragias debido a la posible interferencia de los componentes de la planta con la coagulación sanguínea. En pacientes tratados con metformina, la planta podría exacerbar la reducción de la glucemia, induciendo episodios de hipoglucemia severa.
Otras plantas estudiadas para Diabetes y control glucémico
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