Cinnamomum para Deterioro cognitivo leve
Cinnamomum camphora — 5 estudios científicos revisados
Preliminary¿Sirve Cinnamomum para deterioro cognitivo leve?
Estudios sugieren que el aceite de la variedad borneol tiene efectos de mejora cognitiva, posiblemente a través de la interacción con sistemas neuroquímicos, aunque su seguridad clínica aún es incierta (PMID 39041145).
Compuestos activos involucrados: Aceite esencial, Linalool, Sabineno, Terpenos
Evidencia Científica
Los siguientes estudios han investigado la relación entre Cinnamomum y deterioro cognitivo leve:
Anti-tumor effects of Cinnamomum camphora essential oil in breast cancer via NOX4 modulation by (+)-2-bornanone.
BACKGROUND: Breast cancer (BC) is the most prevalent malignancy among women. Cinnamomum camphora essential oil (CCEO) has shown potential in cancer therapy, but its anti-tumor components and mechanisms in BC remain unclear. NADPH oxidase 4 (NOX4) is an important producer of reactive oxygen species (ROS), driving cancer progression and serving as a potential therapeutic target. PURPOSE: To investigate the anti-tumor activity of CCEO, characterize its active compounds, and clarify its molecular mechanisms. METHODS: The anti-tumor effects of CCEO were assessed in BC cell lines via MTT assays, wes
PubMed: 41016298Review of Cinnamomum camphora Seed Kernel Oil: Extraction, Composition, Health Benefits, Safety, and Food Applications.
Medium-chain triglycerides (MCT) are fatty acid esters with 8-12 carbon atoms that exhibit unique metabolic pathways, making them highly valuable as functional food ingredients. In recent years, Cinnamomum camphora seed kernel oil (CCSKO) has been identified as a natural source of MCT oil, with a composition of over 92% medium-chain fatty acids. As the demand for MCT oil increases, the research into the nutritional and healthcare value and applications of CCSKO is growing. This review provides comprehensive information on the recent research progress on CCSKO, including the extraction method,
PubMed: 41940721Lignan-rich extract from Cinnamomum camphora leaf attenuates metabolic syndrome by modulating glycolipid metabolism and gut microbiota in T2DM mice.
BACKGROUND: Type 2 diabetes mellitus (T2DM) is a serious metabolic syndrome with high mortality and disability rates globally, which usually caused by unhealthy dietary patterns. Cinnamomum camphora leaf is a traditional Chinese medicinal herb used for attenuating hyperglycemia and digestive disorder, and high level of lignans has been found in C. camphora leaf. PURPOSE: This study aimed to examine the chemical composition of lignans extracted from C. camphora leaf (LCCL), and illustrate its therapeutic effect and mechanism on T2DM and its concomitant glycolipid metabolic disorder.
PubMed: 39489989Transcriptome analysis and identification of genes related to terpenoid biosynthesis in Cinnamomum camphora.
BACKGROUND: Cinnamomum camphora has been cultivated as an economically important tree for its medicinal and aromatic properties. Selective breeding has produced Cinnamomum plants for special uses, including spice strains with characteristic flavors and aromas and high-potency medicinal cultivars. The molecular biology underlying terpenoid biosynthesis is still unexplored. RESULTS: Gas chromatography-mass spectrometry was used to analyze the differences in contents and compositions of essential oil terpenoids in linalool- and borneol-type chemotypes of C. camphora.
PubMed: 30041601Identification of algicidal monoterpenoids from four chemotypes of Cinnamomum camphora and their algicidal mechanisms on Microcystis aeruginosa.
Cyanobacterial blooms cause serious environmental issues, and plant secondary metabolites are considered as new algaecide for controlling them. Cinnamomum camphora produces a wide spectrum of terpenoids and has 4 main chemotypes, including linalool, camphor, eucalyptol and borneol chemotype. To develop the new cyanobacterial algaecide by using suitable chemotype of Cinnamomum camphora and the main terpenoids, we analyzed the terpenoid composition in the 4 chemotype extracts, evaluated the algicidal effects of the extracts and their typical monoterpenoids on Microcystis aeruginosa, and investig
PubMed: 37989462Seguridad y Precauciones
El uso de Cinnamomum camphora, especialmente a través de su aceite esencial rico en monoterpenos como el 1,8-cineole y el α-terpineol, requiere una precaución extrema debido a su potente actividad biológica. En el contexto del embarazo y la lactancia, el uso de este arbusto está estrictamente contraindicado. Los compuestos volátiles como el alcanfor pueden atravesar la barrera placentaria y la barrera hematoencefálica, lo que representa un riesgo potencial de neurotoxicidad para el feto en desarrollo. No existen estudios clínicos que aseguren la inocuidad de estos componentes en el desarrollo embrionario; por lo tanto, se debe evitar cualquier exposición para prevenir posibles efectos teratogénicos o complicaciones en el parto. En cuanto a la población pediátrica, el uso en niños menores de 12 años debe evitarse de manera absoluta. Los sistemas enzimáticos y metabólicos de los niños, particularmente su barrera hematoencefálica, son más permeables y vulnerables a los efectos de los monoterpenos, los cuales pueden provocar convulsiones, irritación de las mucosas o depresión del sistema nervioso central en dosis que para un adulto podrían ser insignificantes.
Otras plantas estudiadas para Deterioro cognitivo leve
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