Ehretia tinifolia para Diabetes y control glucémico
Ehretia tinifolia — 4 estudios científicos revisados
Moderate¿Sirve Ehretia tinifolia para diabetes y control glucémico?
Uso documentado en la medicina tradicional y respaldado por investigación preliminar
Compuestos activos involucrados: Flavonoides, Quercetina, Rutina, Saponinas, Terpenos, Pentosidina, Vesperlisina
Evidencia Científica
Los siguientes estudios han investigado la relación entre Ehretia tinifolia y diabetes y control glucémico:
Anti-Advanced Glycation End-product and Free Radical Scavenging Activity of Plants from the Yucatecan Flora.
BACKGROUND: Formation and accumulation of advanced glycation end-products (AGE) is recognized as a major pathogenic process in diabetic complications, atherosclerosis and cardiovascular diseases. In addition, reactive oxygen species and free radicals have also been reported to participate in AGE formation and in cell damage. Natural products with antioxidant and antiAGE activity have great therapeutic potential in the treatment of diabetes, hypertension and related complications. Objective: to test ethanolic extracts and aqueous-traditional preparations of plants used to treat diabetes, hypert
PubMed: 27695268Phytochemical Compositions and
BACKGROUND: OBJECTIVE: The current study investigates bioactive constituents and MATERIALS AND METHODS: Phytochemical investigation and antioxidant assays were carried out using standard procedures. Antidiabetic potential was assessed by evaluating the inhibitory effects of the fractions on the activities of α-amylase and α-glucosidase, while bioactive constituent's identification was carried out using gas chromatography-mass spectrometric (GC-MS) analysis. RESULTS: The phytochemistry tests of the fractions revealed the presence of tannins, phenols, flavonoids, steroids, terpene, alkaloid, a
PubMed: 29142401Phenolic profiles, antioxidant, antiproliferative, and hypoglycemic activities of Ehretia macrophyla Wall. (EMW) fruit.
Phenolic profiles, antioxidant, antiproliferative, and hypoglycemic activities of the whole Ehretia macrophylla Wall. (EMW) fruit were investigated in the present study. Catechin (CE), o-methoxy benzoic acid (o-MBA), and rosmarinic acid (RA) were the predominant phenolics in free extract, while CE, vanillic acid (VA), and o-MBA were for bound extract. These extracts exhibited potential antioxidant capacity measured by peroxyl radical scavenging capacity (PSC), oxygen radical absorbance capacity (ORAC), and cellular antioxidant activity (CAA) assays. This fruit also possessed dose-dependently a
PubMed: 32672871Anti-inflammatory, cytotoxic, and potential wound healing effects of phytofabricated Ehretia rigida leaf aqueous extract-synthesized silver nanoparticles.
Chronic wounds are a global burden, which is escalated by diabetes, infections, and antimicrobial resistance. As a result, the combination of traditional herbal remedies with green nanotechnology has gained attention for developing novel and sustainable therapeutic solutions. Despite the promising biological activities of Ehretia rigida (Er), its potential in nanotechnology-driven wound healing remains unexplored. This study investigated the in vitro anti-inflammatory, cytotoxic, and potential wound-healing effects of Er silver nanoparticles (Er-AgNPs). The stability of the Er-AgNPs was tested
PubMed: 41249433Seguridad y Precauciones
El uso de Ehretia tinifolia debe abordarse con extrema cautela debido a la ausencia de estudios clínicos extensos en humanos que definan perfiles de seguridad definitivos. En el caso de mujeres embarazadas o en periodo de lactancia, no existe evidencia científica que garantice la ausencia de efectos teratogénicos (malformaciones fetales) o de transferencia de metabolitos a través de la leche materna. Dado que el género Ehretia contiene compuestos bioactivos como flavonoides y fenoles que pueden influir en procesos celulares, el riesgo de interferencia con el desarrollo embrionario es una preocupación clínica válida. En niños menores de 12 años, el uso está estrictamente desaconsejado, ya que sus sistemas metabólicos, renales y hepáticos están en desarrollo y son más susceptibles a la toxicidad por compuestos químicos que en adultos. Respecto a las interacciones farmacológicas, se debe prestar especial atención a los siguientes grupos: (1) Fármacos antidiabéticos (como la metformina): Debido a que extractos de raíces de esta especie han mostrado actividad contra productos de glicación avanzada (AGE) y potencial efecto sobre la glucosa [PMID 27695268], su uso concomitante podría potenciar el efecto hipoglucemiante, aumentando el riesgo de hipoglucemia severa. (2) Antihipertensivos: Si la planta posee efectos sobre la presión arterial, podría causar hipotensión ortostática al combinarse con fármacos para la hipertensión.
Otras plantas estudiadas para Diabetes y control glucémico
Perfil completo: Ver todos los usos y evidencia de Ehretia tinifolia →