Maitén para Inflamación
Maytenus boaria — 4 estudios científicos revisados
Preliminary¿Sirve Maitén para inflamación?
Presencia de sesquiterpenos con potencial actividad biológica.
Compuestos activos involucrados: Fenoles, Flavonoides, Polifenoles, Taninos, Terpenos, ácido oleanólico, Compuestos fenólicos
Evidencia Científica
Los siguientes estudios han investigado la relación entre Maitén y inflamación:
Maytenus robusta Reissek, a medicinal plant popularly used to treat digestive diseases, promotes ameliorative effects in colon and liver of mice exposed to dextran sulfate sodium.
ETHNOPHARMACOLOGICAL RELEVANCE: Maytenus robusta Reissek (Celesteraceae), popularly named as cafezinho do mato or coração de bugre, is employed to treat inflammatory digestive diseases in the south of Brazil. However, despite popular usage, the effects of this species on an experimental model of ulcerative colitis are unknown. AIM OF THE STUDY: To evaluate the effects of M. robusta extract (HEMR) on colon and liver from mice with colitis induced by dextran sulfate sodium (DSS). MATERIALS AND METHODS: Firstly, the cytotoxicity of HEMR and its effects on ROS and nitrite production in IEC-6 cells
PubMed: 32730884Phenolic and quinone methide nor-triterpenes as selective NLRP3 inflammasome inhibitors.
Dysregulated inflammasome activity, particularly of the NLRP3 inflammasome, is associated with the development of several inflammatory diseases. The study of molecules directly targeting NLRP3 is an emerging field in the discovery of new therapeutic compounds for the treatment of inflammatory disorders. Friedelane triterpenes are biologically active phytochemicals having a wide range of activities including anti-inflammatory effects. In this work, we evaluated the potential anti-inflammatory activity of phenolic and quinonemethide nor-triterpenes (1-11) isolated from Maytenus retusa and some s
PubMed: 36657273Medicinal plants in Brazil: Pharmacological studies, drug discovery, challenges and perspectives.
This review article focuses on pre-clinical and clinical studies with some selected Brazilian medicinal plants in different areas of interest, conducted by research groups in Brazil and abroad. It also highlights the Brazilian market of herbal products and the efforts of Brazilian scientists to develop new phytomedicines. This review is divided into three sections. The section I describes the Brazilian large biodiversity and some attempts of Brazilian scientists to assess the pharmacological profile of most plant extracts or isolated active principles. Of note, Brazilian scientists have made a
PubMed: 26812486Maytenus heterophylla and Maytenus senegalensis, two traditional herbal medicines.
Maytenus heterophylla (Eckl. and Zeyh.) N.K.B. Robson and Maytenus senegalensis (Lam.) Exell are two African shrubs or trees that go under the common name of spike thorn, which belong to the Celastraceae family. Different plant parts of this species are largely used in traditional medicine for infectious and inflammatory diseases treatment. Several studies have been reported for both these species, but there are no recent review articles focusing microscopic, phytochemistry and pharmacological studies.
PubMed: 22470236Seguridad y Precauciones
Seguridad y Precauciones de Uso: Maitén (Maytenus boaria) Debido a la complejidad de sus metabolitos secundarios, como los sesquiterpenos de tipo dihydro-β-agarofuran identificados en sus estructuras [PMID 28579566, PMID 29726465], el uso de preparados derivados del Maitén debe realizarse con extrema precaución y bajo supervisión profesional. A continuación, se detallan las advertencias de seguridad fundamentales para el manejo de esta especie. En lo que respecta al embarazo y la lactancia, no existe evidencia científica suficiente que garantice la inocuidad de los compuestos bioactivos del Maitén en mujeres gestantes o en periodo de lactancia. Debido a la falta de estudios clínicos sobre la teratogenicidad de sus componentes, se recomienda evitar su consumo durante estas etapas críticas del desarrollo, ya que el riesgo de efectos adversos sobre el feto o el lactante es desconocido. De igual manera, su uso en niños pequeños debe ser evitado, dada la ausencia de protocolos de dosificación segura y la vulnerabilidad de los sistemas fisiológicos en desarrollo ante compuestos químicos complejos. En cuanto a los efectos secundarios conocidos, el uso de extractos concentrados podría provocar reacciones adversas gastrointestinales o dermatológicas en personas sensibles.
Otras plantas estudiadas para Inflamación
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