Miconia theaezans para Inflamación
Miconia theaezans — 6 estudios científicos revisados
Moderate¿Sirve Miconia theaezans para inflamación?
Los flavonoides presentes en la planta actúan inhibiendo mediadores químicos de la respuesta inflamatoria.
Compuestos activos involucrados: Flavonoides, Kaempferol, Terpenos, Fenoles, Polifenoles, Taninos, Compuestos fenólicos
Evidencia Científica
Los siguientes estudios han investigado la relación entre Miconia theaezans y inflamación:
Dereplication and quantification of the ethanol extract of Miconia albicans (Melastomaceae) by HPLC-DAD-ESI-/MS/MS, and assessment of its anti-hyperalgesic and anti-inflammatory profiles in a mice arthritis-like model: Evidence for involvement of TNF-α, IL-1β and IL-6.
ETHNOPHARMACOLOGICAL RELEVANCE: Miconia albicans (Sw) Triana (Melastomataceae), a medicinal plant widely used by practitioners of folk medicine in the northeast of Brazil, has been used to treat chronic inflammatory disorders, such as rheumatoid arthritis (RA) and other joint conditions. Oddly, there is little research on the species. AIM OF THE STUDY: We aimed to evaluate the anti-arthritic and anti-inflammatory profile of the ethanolic leaf extract of M. albicans (EEMA), as well as to perform dereplication and quantification by HPLC-DAD-ESI-/MS/MS. MATERIALS AND METHODS: The compounds presen
PubMed: 32387232Anti-inflammatory and antinociceptive activities of the leaf methanol extract of Miconia minutiflora (Bonpl.) DC. and characterization of compounds by UPLC-DAD-QTOF-MS/MS.
Some species of the genus Miconia are used in Brazilian folk medicine as analgesic and anti-inflammatory; however, several species of this genus are still poorly studied. Therefore, the aims of this study were to investigate the phytochemistry characterization by UPLC-DAD-QTOF-MS/MS, acute toxicity, anti-inflammatory and antinociceptive properties of Miconia minutiflora (Bonpl.) DC. The methanol extract of M. minutiflora (Mm-MeOH) was subjected to ultra-high-performance liquid chromatography (UPLC-DAD-QTOF-MS/MS) for the identification of the main phytocompounds. The anti-inflammatory properti
PubMed: 30215112Infusion from Miconia albicans (Melastomataceae) leaves exhibits anti-inflammatory and anti-hyperalgesic activities without toxicity.
ETHNOPHARMACOLOGICAL RELEVANCE: The leaves of Miconia albicans have been extensively used as a traditional medicine to treat inflammation, infection, arthritis, joint pain, and analgesia, which can be purchased easily. Nevertheless, the scientific evidence of chemical profile identification and toxicity investigation is meager. AIM OF THE STUDY: This study aimed to determine the chemical profile of Miconia albicans aqueous extract (MAAE), to investigate its anti-inflammatory and hyperalgesic effects, and toxicity (acute and repeated-dose oral) in vivo studies. MATERIALS AND METHODS: MAAE was o
PubMed: 36791930Miconia albicans and Curcuma longa herbal medicines positively modulate joint pain, function and inflammation in patients with osteoarthritis: a clinical study.
This study aims to evaluate the analgesic and modulating effect of Curcuma longa and Miconia albicans herbal medicines in knee's osteoarthritis (OA) treatment. This longitudinal study evaluated 24 patients with OA. The patients were divided into three groups: ibuprofen (1200 mg/day), C. longa (1000 mg/day) and M. albicans (1000 mg/day).
PubMed: 33452967Seguridad y Precauciones
La seguridad del uso de Miconia theaezans no ha sido establecida mediante ensayos clínicos controlados en humanos, lo que representa una limitación crítica para su consumo terapéutico y requiere extrema precaución. En cuanto al embarazo y la lactancia, no existen estudios que garanticen la ausencia de efectos teratogénicos o la transferencia de metabolitos secundarios a través de la leche materna; por tanto, se desaconseja su uso debido al riesgo potencial de que los compuestos fenólicos interfieran con el desarrollo embrionario o la nutrición del lactante. Para niños menores de 12 años, la falta de datos sobre la toxicidad aguda y crónica en organismos en desarrollo impide su recomendación, siendo especialmente delicada la sensibilidad de su mucosa gastrointestinal a los taninos presentes en la planta. Respecto a las interacciones farmacológicas, existe un riesgo teórico significativo con la warfarina, ya que los flavonoides presentes en el género Miconia pueden alterar la cascada de coagulación o la actividad de la vitamina K, modificando el tiempo de protrombina. Con la metformina, los taninos podrían quelar el fármaco o alterar su absorción intestinal, afectando el control glucémico. Asimismo, en pacientes que toman antihipertensivos, la posible acción vasodilatadora de los polifenoles podría potenciar el efecto hipotensor, provocando desmayos o mareos por hipotensión excesiva.
Otras plantas estudiadas para Inflamación
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