Myrcia para Estrés oxidativo
Myrcia bella — 5 estudios científicos revisados
Moderate¿Sirve Myrcia para estrés oxidativo?
Uso documentado en la medicina tradicional y respaldado por investigación preliminar
Compuestos activos involucrados:
Evidencia Científica
Los siguientes estudios han investigado la relación entre Myrcia y estrés oxidativo:
Antimutagenicity and induction of antioxidant defense by flavonoid rich extract of Myrcia bella Cambess. in normal and tumor gastric cells.
ETHNOPHARMACOLOGICAL RELEVANCE: The Brazilian "Cerrado" is an important source of natural products, such as Myrcia bella Cambess (MB, also known as "mercurinho"). MB leaves are popularly used for the treatment of diabetes and gastrointestinal disorders; however, only its hypoglycemic activity has been experimentally described. AIM OF THE STUDY: Because MB is used to treat gastrointestinal disorders, the present study characterized biological activities of hydroalcoholic MB extract in human normal and tumor gastric cells. MATERIALS AND METHODS: Cytotoxic, antiproliferative, genotoxic and protec
PubMed: 26549270The Effect of Solutions Containing Extracts of Vochysia tucanorum Mart., Myrcia bellaCambess., Matricaria chamomilla L. and Malva sylvestris L. on Cariogenic Bacterial Species and Enamel Caries Development.
This study evaluated the effect of experimental solutions containing plant extracts on bacterial species and enamel caries prevention. Microcosm biofilm was produced from human saliva mixed with McBain saliva (0.2% sucrose) on bovine enamel for 5 days (3 days under anaerobiosis and 2 days under aerobiosis) at 37°C. From the 2nd day, the following treatments were applied (1 × 60 s/day): Vochysia tucanorum (10 mg/mL); Myrcia bella (5 mg/mL); Matricaria chamomilla (80 mg/mL); Malva sylvestris, fluoride, and xylitol (Malvatricin Plus®); 0.12% chlorhexidine (CHX, PerioGard®); and PBS (negative cont
PubMed: 34000728The Effect of Toothpastes Containing Natural Extracts on Bacterial Species of a Microcosm Biofilm and on Enamel Caries Development.
This study investigated the effects of herbal toothpaste on bacterial counts and enamel demineralization. Thirty-six bovine enamel samples were exposed to a microcosm biofilm using human saliva and McBain saliva (0.2% sucrose) for 5 days at 37 °C and first incubated anaerobically, then aerobically-capnophilically. The following experimental toothpaste slurries (2 × 2 min/day) were applied: (1)
PubMed: 35326877Antioxidant activity and phenolic content of leaf infusions of Myrtaceae species from Cerrado (Brazilian Savanna).
There is considerable interest in identifying new antioxidants from plant materials. Several studies have emphasized the antioxidant activity of species belonging to the Myrtaceae family. However, there are few reports on these species from the Cerrado (Brazilian savanna). In this study, the antioxidant activity and phenolic content of 12 native Myrtaceae species from the Cerrado were evaluated (Blepharocalyx salicifolius, Eugenia bimarginata, Eugenia dysenterica, Eugenia klotzschiana, Hexachlamys edulis, Myrcia bella, Myrcia lingua, Myrcia splendens, Myrcia tomentosa, Psidium australe, Psidiu
PubMed: 26675912Antibiofilm and anti-caries effects of an experimental mouth rinse containing Matricaria chamomilla L. extract under microcosm biofilm on enamel.
OBJECTIVE: This study evaluated the antibiofilm and anti-caries effects of an experimental mouth rinse containing aqueous extract of Matricaria chamomilla L. METHODS: Microcosm biofilm was produced on bovine enamel, from pooled human saliva mixed with McBain saliva, under 0.2 % sucrose exposure, for 5 days. The biofilm was daily treated using (1 mL/1 min): Vochysia tucanorum Mart. (2.5 mg/mL); Myrcia bella Cambess. (1.25 mg/mL); Matricaria chamomilla L.
PubMed: 32592827Contexto Científico
The study observed that the extract caused cell death through necrosis and induced an arrest in the G2/M phase of the cell cycle, which means it prevents cells from dividing. Additionally, the extract showed antimutagenic effects, meaning it might help prevent genetic mutations, likely due to its antioxidant activity (PMID 26549270). Finally, the antioxidant potential of Myrcia bella was compared to other native species of the Myrtaceae family. The study looked at the total phenolic content (TPC) and the antioxidant activity index (AAI) of various species from the Cerrado. Myrcia bella was noted for its high phenolic content, which is strongly correlated with its ability to act as an antioxidant.
Seguridad y Precauciones
El uso de Myrcia bella (conocida popularmente en el Cerrado brasileño como 'mercurinho') requiere una precaución extrema debido a su potente actividad biológica, especialmente su efecto hipoglucemiante. En el caso de mujeres embarazadas o en periodo de lactancia, no existe evidencia científica que garantice la seguridad del consumo de extractos de Myrcia bella en estos estados fisiológicos. Dado que la planta interactúa con las vías de señalización de la insulina (PI3k/Akt), existe un riesgo teórico de que los compuestos puedan atravesar la barrera placentaria o pasar a la leche materna, afectando el metabolismo glucémico del feto o del lactante. Debido a la falta de estudios de toxicidad reproductiva, su uso está contraindicado en estas poblaciones. Para niños menores de 12 años, el uso debe evitarse estrictamente. Los sistemas metabólicos en desarrollo son altamente sensibles a las fluctuaciones de glucosa y a los compuestos fenólicos; la administración de dosis no estandarizadas podría provocar hipoglucemia severa en infantes, cuya regulación glucémica es distinta a la de los adultos.
Otras plantas estudiadas para Estrés oxidativo
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