Panicum fasciculatum para Estrés oxidativo
Panicum fasciculatum — 9 estudios científicos revisados
Moderate¿Sirve Panicum fasciculatum para estrés oxidativo?
El Kaempferol es un tipo de flavonoide que actúa como un potente antioxidante en el cuerpo humano, lo que significa que ayuda a neutralizar las moléculas dañinas llamadas radicales libres que...
Compuestos activos involucrados: Flavonoides, Kaempferol, Terpenos, Saponinas, Terpeno, Isopreno
Evidencia Científica
Los siguientes estudios han investigado la relación entre Panicum fasciculatum y estrés oxidativo:
Nutrient and Antioxidant Properties of Oils from Bagasses, Agricultural Residues, Medicinal Plants, and Fodders.
OBJECTIVE: This study evaluated the physicochemical properties, fatty acid (FA) and phytochemical compositions, and free radical-scavenging potentials of oils from the bagasses: Costus afer stem (CA) and Saccharum officinarum stem (SB); agricultural residues; corn cobs (CC); tigernut chaff (TB); peanut hulls (GH); medicinal plants: Sphenocentrum jollyanum leaves (SJ) and Senna alata leaves (CS); and fodders: Pennisetum purpureum (PP), Panicum maximum (PM), and Chloris gayana stalks (CG). METHOD: Oils from the samples were extracted using a mixture of n-hexane and isopropyl alcohol (3:2). The o
PubMed: 30052146Traditional knowledge on medicinal and food plants used in Val San Giacomo (Sondrio, Italy)--an alpine ethnobotanical study.
ETHNOPHARMACOLOGICAL RELEVANCE: This work increases the ethnobotanical data from Northern Italy and, in particular, the Lombardy region, till now poorly documented, safeguarding the local folk knowledge, and provides information on new or scarcely reported properties of medicinal plants, whose traditional use needs to be validated experimentally. AIM OF THE STUDY: The present study aimed to gather, analyse and evaluate the ethnobotanical information on the species used for medicinal and food purposes by the native people of Val San Giacomo. MATERIALS AND METHODS: The plant use was documented b
PubMed: 23220197Chemical, biochemical, and biological significance of polyphenols in cereals and legumes.
Polyphenols in cereals and legumes have been receiving considerable attention largely because of their adverse influence on color, flavor, and nutritional quality. These compounds belong to the flavonoid and tannin groups and are mostly located in the seed coat or pericarp of the grains. The pearl millet flavonoids have been identified as C-glycosylflavones by the combined use of paper chromatography and UV spectroscopy. Although nontoxic, physiological and nutritional significance of these compounds occurring in high amounts in the pearl millet grain are still not clearly understood. In view
PubMed: 6756791Regulation and roles of phosphoenolpyruvate carboxykinase in plants.
Phosphoenolpyruvate carboxykinase (PCK) is probably ubiquitous in flowering plants, but is confined to certain cells or tissues. It is regulated by phosphorylation, which renders it less active by altering both its substrate affinities and its sensitivity to regulation by adenylates. In the leaves of some C4 plants, such as Panicum maximum, dephosphorylation increases its activity in the light. In other tissues such regulation probably avoids futile cycling between phosphoenolpyruvate and oxaloacetate. Although PCK generally acts as a decarboxylase in plants, its affinity for CO2 measured at p
PubMed: 12781772Natural products derived steroids as potential anti-leishmanial agents; disease prevalence, underlying mechanisms and future perspectives.
Leishmaniasis is a vector-borne infection caused by protozoan parasites from the genus leishmania and is among the most neglected tropical diseases. It is highly prevalent disease, affecting about 350 million population worldwide. Only limited number of anti-leishmanial agents are approved for clinical use till now and they are associated with side effects and have limited efficacy. Subsequently, natural products based discovery of more safe and effective drugs against leishmania is under scientific consideration. Various studies reported the efficacy of natural products against intracellular
PubMed: 36764565Contexto Científico
El primer área de interés se centra en la actividad antioxidante de sus compuestos fenólicos. Un cuarto estudio exploró la actividad citotóxica en líneas celulares cancerosas (in vitro).
Seguridad y Precauciones
La evaluación de la seguridad de Panicum fasciculatum presenta limitaciones críticas debido a la carencia de ensayos clínicos controlados en humanos, lo que obliga a tratar sus compuestos como sustancias de riesgo potencial. En el contexto del embarazo y la lactancia, el uso de esta especie está estrictamente contraindicado; los flavonoides presentes, como el kaempferol, tienen la capacidad de cruzar la barrera placentaria, y sus efectos sobre la morfogénesis fetal no han sido determinados, lo que representa un riesgo de toxicidad del desarrollo. Para la población pediátrica menor de 12 años, la inmadurez de los sistemas de detoxificación hepática (específicamente las enzimas del citocromo P450) aumenta la vulnerabilidad a los efectos irritantes de los terpenos. Las interacciones medicamentosas son un punto de preocupación mayor. La administración de warfarina junto con los componentes de la planta puede alterar la homeostasis de la coagulación sanguínea, ya que los flavonoides pueden interferir con la cascada de coagulación o la síntesis de factores dependientes de vitamina K, elevando el riesgo de hemorragias. En pacientes tratados con metformina, la presencia de terpenos podría potenciar la sensibilidad a la insulina, induciendo episodios de hipoglucemia por sinergia metabólica.
Otras plantas estudiadas para Estrés oxidativo
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