Rosa para Estrés oxidativo
Rosa canina — 15 estudios científicos revisados
Strong¿Sirve Rosa para estrés oxidativo?
Posee una potente capacidad de eliminación de radicales libres gracias a su alto contenido de compuestos fenólicos, carotenoides y vitamina C, protegiendo las células del daño molecular.
Compuestos activos involucrados: Caroteno, Fenoles, Flavonoides, Galactolípido, Saponinas, Terpenoides, Terpenos, Vitamina, Vitamina a, ácido, Carotenoides, Compuestos fenólicos, ácidos grasos
Evidencia Científica
Los siguientes estudios han investigado la relación entre Rosa y estrés oxidativo:
Polyphenolic Composition of
The aim of the present study was the investigation of the antioxidant activity of plant extracts from Rosa canina, Rosa sempervivens and Pyrocantha coccinea. The results showed that the bioactive compounds found at higher concentrations were in the R. canina extract: hyperoside, astragalin, rutin, (+)-catechin and (-)-epicatechin; in the R. sempervirens extract: quinic acid, (+)-catechin, (-)-epicatechin, astragalin and hyperoside; and in the P. coccinea extract: hyperoside, rutin, (-)-epicatechin, (+)-catechin, astragalin, vanillin, syringic acid and chlorogenic acid.
PubMed: 30959906Rosa canina - Rose hip pharmacological ingredients and molecular mechanics counteracting osteoarthritis - A systematic review.
BACKGROUND: The successful use of rose hip for the treatment of osteoarthritis is well documented. Several randomized placebo controlled double-blind studies, as mono or combination therapy, have demonstrated treatment efficacy as well as excellent tolerability. PURPOSE: This review focuses on the molecular mechanism underlying the clinical effects of rose hip in osteoarthritis (OA). METHODS: The database Medline was screened - using the search term "Rosa canina" or "rose hip" - for publications on pharmacological or mechanistic studies with relevance to OA; in addition for findings on pharmac
PubMed: 31138475Effect of
BACKGROUND AND OBJECTIVE: In spite of therapeutic effect of tamoxifen on the breast cancer, it has some side effects on the liver including non-alcoholic fatty liver disease. In this study the effects of Rosa canina distilled water on the tamoxifen-induced fatty liver and oxidative stress status in male rats were investigated. MATERIALS AND METHODS: Twenty four adult male Wistar rats were randomly divided into 4 groups of 6: 1st group: Untreated control rats (C), 2nd group (T): The rats received tamoxifen, 3rd group (T+R): Rats received tamoxifen and Rosa canina distilled water and 4th group (
PubMed: 31944077Rosa canina L. methanolic extract prevents heat stress-induced memory dysfunction in rats.
NEW FINDINGS: What is the central question of this study? Heat stress has harmful effects on the brain structure and synaptic density via induction of oxidative stress and neuroinflammation, which result in neuronal damage in the hippocampus and thereby cognitive impairments. In this study, we investigate the effect of Rosa canina treatment on cognitive function in heat stress-exposed rats and its underlying mechanisms. What is the main finding and its importance? We show that R.
PubMed: 31297904Recent advances and insights into the bioactive properties and applications of
Rosa canina L., commonly known as rosehip, is of notable scientific interest for its applications in nutrition, cosmetics, and pharmaceuticals. This review article highlights its health-promoting properties, including antioxidant, anti-inflammatory, hepatoprotective, and anticarcinogenic effects, attributed to its rich content of phenolic acids, carotenoids, tocopherols, and vitamins. With growing interest in sustainable practices, rosehip by-products are increasingly valorized. For instance, cold-pressed rosehip seed oil is a valuable source of polyunsaturated fatty acids, while incorporating
PubMed: 38765085Contexto Científico
La investigación científica sobre Rosa canina ha pasado de la observación tradicional a la validación de mecanismos moleculares complejos. El primer estudio (PMID 38824245) investigó el efecto del extracto de Rosa canina sobre la diabetes. El método consistió en la administración diaria de agua destilada de Rosa canina. El método consistió en la administración de extracto etanólico de Rosa canina. El método comparó diferentes dosis de extracto metanólico de Rosa canina.
Seguridad y Precauciones
El uso de Rosa canina (escaramujo) requiere precaución debido a su actividad biológica sobre diversos sistemas metabólicos. En el caso de mujeres embarazadas o en periodo de lactancia, no existe evidencia clínica suficiente en humanos que garantice la seguridad total del consumo de extractos concentrados; por lo tanto, se recomienda evitar su uso terapéutico para prevenir cualquier riesgo de interferencia con el desarrollo fetal o la transferencia de compuestos bioactivos a través de la leche materna. En niños menores de 12 años, la seguridad no ha sido establecida mediante estudios controlados, y debido a que su sistema enzimático y metabólico está en desarrollo, se debe evitar el uso de dosis terapéuticas sin supervisión médica estricta. Respecto a las interacciones farmacológicas, es crítico considerar su efecto hipoglucemiante. Al combinarse con fármacos como la metformina o la insulina, Rosa canina podría potenciar la reducción de la glucosa en sangre, aumentando el riesgo de hipoglucemia (niveles peligrosamente bajos de azúcar). Asimismo, debido a su potencial efecto sobre la presión arterial y la función cardiovascular, su uso concomitante con antihipertensivos debe ser monitoreado para evitar hipotensión.
Otras plantas estudiadas para Estrés oxidativo
Perfil completo: Ver todos los usos y evidencia de Rosa →