Salvia para Estrés oxidativo
Salvia blancoana — 14 estudios científicos revisados
Moderate¿Sirve Salvia para estrés oxidativo?
Uso documentado en la medicina tradicional y respaldado por investigación preliminar
Compuestos activos involucrados: Flavonoides, Polifenoles, Terpenos
Evidencia Científica
Los siguientes estudios han investigado la relación entre Salvia y estrés oxidativo:
The antioxidant, antidiabetic, and antihyperlipidemic effects of the polyphenolic extract from Salvia blancoana subsp. mesatlantica on induced diabetes in rats.
Currently, several studies have demonstrated the benefits of medicinal plants in managing type 2 diabetes. In this work, we evaluated the beneficial effects of the polyphenolic extract (PESB) from Salvia blancoana subsp. mesatlantica in the management of hypercaloric-feeding and small-dose alloxan-brought type 2 diabetes in rats. We analyzed the chemical constituents of the extract, including flavones and flavonols content, to understand its biological action. The antioxidant activities were evaluated by total antioxidant action, scavenging effect of the free radical DPPH, and reducing power.
PubMed: 38926327Sub-chronic and acute toxicity of aqueous extracts
BACKGROUND: OBJECTIVE: Our study aimed to evaluate the SBm-extract for both acute and sub-chronic toxicity. METHODS: Aqueous extracts were obtained from the aerial parts of SBm collected from Immouzer Kander commune (Middle Atlas, Morocco). Total Phenolic Content (TPC) and Flavones and flavonols Content (FFC), Antioxidant activity (2,2-diphenyl-1-picrylhydrazyl (DPPH) and reducing power) was determined, and chemical composition was determined by High-Performance Liquid Chromatography with Diode Array Detection (HPLC-DAD). Toxicity tests were conducted on mice and rats. RESULTS: In acute toxic
PubMed: 39703767Medicinal Plants in Traditional Herbal Wines and Liquors in the East of Spain and the Balearic Islands.
Homemade herbal preparations from the East of Spain are the witness of traditional medicine inherited from the ancient complex formulas of herbal teas and medicinal wines. In this study, we document the use of traditional alcoholic beverages, identify their ingredients, almost exclusively botanical, record the local medicinal uses of these mixtures, and discuss patterns of distribution of this knowledge in regions of eastern Spain, the Balearic Islands and Andorra. We determine marker species and relevant patterns of herbal formulas in the different regions of the territory. Homemade liquors a
PubMed: 34658855A review of effective herbal medicines in controlling menopausal symptoms.
BACKGROUND: Acute menopausal syndrome especially hot flashes, is one of the most common gynecological problems during menopause. Due to the side effects of hormone therapy, herbal and complementary medicines are always of immense interest to people in the treatment and management of the symptoms and complications of menopause. OBJECTIVE: The aim of this study was to investigate the mechanisms and effects of medicinal plants employed in the treatment of menopausal symptoms. METHODS: This review article was carried out by examining clinical trial studies between the period of 1994 and 2016. The
PubMed: 29403626Adverse effects of herbal medicines: an overview of systematic reviews.
This overview of systematic reviews (SRs) aims to evaluate critically the evidence regarding the adverse effects of herbal medicines (HMs). Five electronic databases were searched to identify all relevant SRs, with 50 SRs of 50 different HMs meeting our inclusion criteria. Most had only minor weaknesses in methods. Serious adverse effects were noted only for four HMs: Herbae pulvis standardisatus, Larrea tridentate, Piper methysticum and Cassia senna. The most severe adverse effects were liver or kidney damage, colon perforation, carcinoma, coma and death.
PubMed: 23472485Contexto Científico
El primer estudio, realizado con el objetivo de evaluar los efectos antioxidantes, antidiabéticos y antihiperlipemiantes del extracto polifenólico de Salvia blancoana subsp. Los resultados mostraron que el extracto posee una capacidad antioxidante significativa, con un valor de capacidad antioxidante total de 593.51 ± 4.09 mg (EAA)/g y un contenido de flavonoides de 7.89 ± 0.05 mg QE/g [PMID 38926327]. En el caso de la Salvia, los registros de efectos adversos suelen clasificarse como menores o moderados en comparación con otras plantas más potentes [PMID 23472485]. Los estudios de toxicidad son fundamentales para asegurar que el uso de la planta no sea perjudicial, pero la transición de resultados en ratas a aplicaciones clínicas seguras en personas requiere de ensayos clínicos humanos más extensos y rigurosos.
Seguridad y Precauciones
El uso de Salvia (Salvia blancoana) requiere una supervisión cuidadosa debido a su actividad biológica. En el caso de embarazo y lactancia, no existe evidencia clínica suficiente que garantice la seguridad para el desarrollo fetal o neonatal; por lo tanto, su uso está contraindicado en estas etapas. El potencial efecto emenagogo (estimulación del flujo sanguíneo en el útero) mencionado en contextos etnobotánicos podría representar un riesgo de aborto espontáneo. Asimismo, la transferencia de compuestos polifenólicos a través de la leche materna no ha sido estudiada exhaustivamente, lo que impide asegurar la ausencia de efectos neurotóxicos o sistémicos en el lactante. Para niños menores de 12 años, la seguridad no está establecida. Los sistemas fisiológicos en desarrollo, particularmente el metabolismo hepático y la barrera hematoencefálica, son más vulnerables a las fluctuaciones de compuestos bioactivos.
Otras plantas estudiadas para Estrés oxidativo
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