Salvia para Estrés oxidativo
Salvia chionantha — 13 estudios científicos revisados
Moderate¿Sirve Salvia para estrés oxidativo?
Uso documentado en la medicina tradicional y respaldado por investigación preliminar
Compuestos activos involucrados:
Evidencia Científica
Los siguientes estudios han investigado la relación entre Salvia y estrés oxidativo:
Chemical composition of the essential oil and hexane extract of Salvia chionantha and their antioxidant and anticholinesterase activities.
The essential oil and methyl ester of hexane extract of Salvia chionantha Boiss. were analysed by GC and GC-MS. Totally, 54 components were detected in the essential oil and all of them were fully determined. Germacrene D (25.03%), β-caryophyllene (8.71%), spathulenol (5.86%) and α-humulene (4.82%) were identified as the major compounds. In the methylated hexane extract, 3-hydroxy hexadecanoic acid (39.39%), 3-hydroxy tetradecanoic acid (12.66%) and palmitic acid (12.02%) were the major fatty acids elucidated.
PubMed: 20732375Preclinical study of the medicinal plants for the treatment of malignant melanoma.
Melanoma is the most aggressive type of skin cancer and originates from pigment-containing cells called melanocytes. The incidence of melanoma has been increasing worldwide. In the current study, the cytotoxic and photo-cytotoxic activities of different medicinal plants from Lamiaceae (Salvia cedronella, Salvia chionantha, and Salvia adenophylla), Asteraceae (Klasea kurdica, Klasea bornmuelleri, and Achillea millefolium), Apiaceae (Cuminum cyminum, and Anethum graveolens), and Polygonaceae (Rumex crispus) families were studied against HT 144 (Human malignant melanoma) cancer cell lines. The ac
PubMed: 32710386A review of effective herbal medicines in controlling menopausal symptoms.
BACKGROUND: Acute menopausal syndrome especially hot flashes, is one of the most common gynecological problems during menopause. Due to the side effects of hormone therapy, herbal and complementary medicines are always of immense interest to people in the treatment and management of the symptoms and complications of menopause. OBJECTIVE: The aim of this study was to investigate the mechanisms and effects of medicinal plants employed in the treatment of menopausal symptoms. METHODS: This review article was carried out by examining clinical trial studies between the period of 1994 and 2016. The
PubMed: 29403626Adverse effects of herbal medicines: an overview of systematic reviews.
This overview of systematic reviews (SRs) aims to evaluate critically the evidence regarding the adverse effects of herbal medicines (HMs). Five electronic databases were searched to identify all relevant SRs, with 50 SRs of 50 different HMs meeting our inclusion criteria. Most had only minor weaknesses in methods. Serious adverse effects were noted only for four HMs: Herbae pulvis standardisatus, Larrea tridentate, Piper methysticum and Cassia senna. The most severe adverse effects were liver or kidney damage, colon perforation, carcinoma, coma and death.
PubMed: 23472485Salvia miltiorrhiza: Traditional medicinal uses, chemistry, and pharmacology.
Salvia miltiorrhiza Bunge (SM) is a very popular medicinal plant that has been extensively applied for many years to treat various diseases, especially coronary heart diseases and cerebrovascular diseases, either alone or in combination with other Chinese plant-based medicines. Although a large number of studies on SM have been performed, they are scattered across a variety of publications. The present review is an up-to-date summary of the published scientific information about the traditional uses, chemical constituents, pharmacological effects, side effects, and drug interactions with SM, i
PubMed: 25835361Contexto Científico
La investigación científica sobre Salvia chionantha se centra principalmente en su actividad celular y su potencial terapéutico frente a enfermedades degenerativas y cancerosas. La pregunta investigada fue si el extracto de Salvia chionantha poseía propiedades antioxidantes y capacidad para inhibir enzimas clave en la enfermedad de Alzheimer. El método consistió en aplicar los extractos a las células cancerosas y medir su supervivencia mediante el ensayo MTT y la citometría de flujo. Los resultados indicaron que los extractos de las especies de Salvia mostraron efectos citotóxicos (capacidad de matar células) y foto-citotóxicos, induciendo la apoptosis (muerte celular programada) a través de la generación de especies reactivas de oxígeno (ROS) mediada por TNF-α. En términos simples, el estudio demostró que la planta puede inducir la muerte de células cancerosas en un entorno controlado, lo que representa un hallazgo prometedor para la investigación oncológica, aunque no significa una cura [PMID 32710386].
Seguridad y Precauciones
La seguridad de Salvia chionantha es un área donde la evidencia científica es actualmente limitada, lo que exige una precaución extrema. En el contexto de embarazo y lactancia, no existen estudios clínicos que determinen la seguridad del consumo de esta especie en mujeres gestantes o lactantes. Debido a la presencia de diterpenoides bioactivos (como la horminona y la 7-O-acetilhorminona, según el PMID 19446421) y compuestos volátiles en su aceite esencial, existe un riesgo potencial de efectos teratogénicos (malformaciones fetales) o de alteración del desarrollo embrionario. En la lactancia, los compuestos bioactivos podrían transferirse a través de la leche materna, con consecuencias impredecibles para el lactante. Por tanto, se desaconseja totalmente su uso en estas etapas. Para niños menores de 12 años, la precaucción debe ser máxima.
Otras plantas estudiadas para Estrés oxidativo
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