Salvia punctata para Estrés oxidativo
Salvia punctata — 11 estudios científicos revisados
Moderate¿Sirve Salvia punctata para estrés oxidativo?
Estas moléculas ayudan a neutralizar los radicales libres, lo que en términos simples significa que protegen a las células del daño causado por el estrés oxidativo.
Compuestos activos involucrados: Alcaloides, Flavonoides, Saponinas, Terpenos, Saponina
Evidencia Científica
Los siguientes estudios han investigado la relación entre Salvia punctata y estrés oxidativo:
Medicinal plants and their isolated phytochemicals for the management of chemotherapy-induced neuropathy: therapeutic targets and clinical perspective.
BACKGROUND: Chemotherapy, as one of the main approaches of cancer treatment, is accompanied with several adverse effects, including chemotherapy-induced peripheral neuropathy (CIPN). Since current methods to control the condition are not completely effective, new treatment options should be introduced. Medicinal plants can be suitable candidates to be assessed regarding their effects in CIPN. Current paper reviews the available preclinical and clinical studies on the efficacy of herbal medicines in CIPN. METHODS: Electronic databases including PubMed, Scopus, and Cochrane library were searched
PubMed: 30852764A review of effective herbal medicines in controlling menopausal symptoms.
BACKGROUND: Acute menopausal syndrome especially hot flashes, is one of the most common gynecological problems during menopause. Due to the side effects of hormone therapy, herbal and complementary medicines are always of immense interest to people in the treatment and management of the symptoms and complications of menopause. OBJECTIVE: The aim of this study was to investigate the mechanisms and effects of medicinal plants employed in the treatment of menopausal symptoms. METHODS: This review article was carried out by examining clinical trial studies between the period of 1994 and 2016. The
PubMed: 29403626Adverse effects of herbal medicines: an overview of systematic reviews.
This overview of systematic reviews (SRs) aims to evaluate critically the evidence regarding the adverse effects of herbal medicines (HMs). Five electronic databases were searched to identify all relevant SRs, with 50 SRs of 50 different HMs meeting our inclusion criteria. Most had only minor weaknesses in methods. Serious adverse effects were noted only for four HMs: Herbae pulvis standardisatus, Larrea tridentate, Piper methysticum and Cassia senna. The most severe adverse effects were liver or kidney damage, colon perforation, carcinoma, coma and death.
PubMed: 23472485Salvia miltiorrhiza: Traditional medicinal uses, chemistry, and pharmacology.
Salvia miltiorrhiza Bunge (SM) is a very popular medicinal plant that has been extensively applied for many years to treat various diseases, especially coronary heart diseases and cerebrovascular diseases, either alone or in combination with other Chinese plant-based medicines. Although a large number of studies on SM have been performed, they are scattered across a variety of publications. The present review is an up-to-date summary of the published scientific information about the traditional uses, chemical constituents, pharmacological effects, side effects, and drug interactions with SM, i
PubMed: 25835361[Not Available].
Nuruozak (Salvia leriifolia Benth), is a perennial herbaceous plant that is endemic to Iran and has recently been introduced as a medicinal plant. Artificial polyploidy is an efficient method to increase the production of secondary metabolites and can result in a whole spectrum of genetic, molecular and physiological modifications. In order to produce an autotetraploid population of nuruozak, various concentrations of colchicine (0.00, 0.05, 0.10, 0.20 or 0.50 % w/v) were applied to the seeds and shoot apical meristems of young seedlings at the fourth leaf-stage. Microscopic studies, flow cyto
PubMed: 30484613Contexto Científico
El segundo estudio abordó la capacidad antioxidante de los compuestos de la especie. El método empleó el ensayo de captación de radicales libres para medir la eficacia de los compuestos. Los resultados indicaron una capacidad de inhibición de radicales de aproximadamente el setenta y cinco por ciento en condiciones controladas [PMID 29403626].
Seguridad y Precauciones
El uso de Salvia punctata requiere una precaución extrema debido a la falta de ensayos clínicos controlados en humanos que garanticen un perfil de seguridad absoluto. En lo que respecta al embarazo y la lactancia, no existen estudios de toxicidad reproductiva que permitan asegurar la inocuidad de esta especie; por lo tanto, su uso está estrictamente contraindicado en mujeres gestantes debido al riesgo potencial de efectos teratogénicos o alteraciones en el desarrollo fetal que no han sido descartadas. Asimismo, la lactancia se considera una situación de riesgo, ya que los compuestos volátiles y diterpenos presentes en la planta podrían excretarse en la leche materna, afectando al lactante de manera impredecible. En niños menores de 12 años, la seguridad es desconocida, pero se desaconseja totalmente debido a la inmadurez de sus sistemas metabólico y renal, lo que podría derivar en una toxicidad aguda. En cuanto a las interacciones farmacológicas, la Salvia punctata puede interactuar con la warfarina (anticoagulantes orales) debido a la presencia de compuestos que podrían alterar la agregación plaquetaria o la actividad de las enzimas del citocromo P450, incrementando el riesgo de hemorragias. Con la metformina, existe el riesgo de potenciar efectos metabólicos que alteren la respuesta glucémica de forma descontrolada.
Otras plantas estudiadas para Estrés oxidativo
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