Salvia para Estrés oxidativo
Salvia tchihatcheffii — 11 estudios científicos revisados
Preclinical¿Sirve Salvia para estrés oxidativo?
Los ácidos fenólicos característicos del género Salvia, particularmente el ácido rosmarínico y el ácido carnósico, exhiben actividad antioxidante documentada en múltiples ensayos preclínicos con especies del género.
Compuestos activos involucrados: Ácido rosmarínico, Ácido carnósico, Carnosol, Ácido ursólico, Ácido oleanólico
Evidencia Científica
Los siguientes estudios han investigado la relación entre Salvia y estrés oxidativo:
A review of effective herbal medicines in controlling menopausal symptoms.
BACKGROUND: Acute menopausal syndrome especially hot flashes, is one of the most common gynecological problems during menopause. Due to the side effects of hormone therapy, herbal and complementary medicines are always of immense interest to people in the treatment and management of the symptoms and complications of menopause. OBJECTIVE: The aim of this study was to investigate the mechanisms and effects of medicinal plants employed in the treatment of menopausal symptoms. METHODS: This review article was carried out by examining clinical trial studies between the period of 1994 and 2016. The
PubMed: 29403626Adverse effects of herbal medicines: an overview of systematic reviews.
This overview of systematic reviews (SRs) aims to evaluate critically the evidence regarding the adverse effects of herbal medicines (HMs). Five electronic databases were searched to identify all relevant SRs, with 50 SRs of 50 different HMs meeting our inclusion criteria. Most had only minor weaknesses in methods. Serious adverse effects were noted only for four HMs: Herbae pulvis standardisatus, Larrea tridentate, Piper methysticum and Cassia senna. The most severe adverse effects were liver or kidney damage, colon perforation, carcinoma, coma and death.
PubMed: 23472485Ethnobotanical diversity of the genus Salvia L. (Lamiaceae): From medicinal and culinary applications to cultural importance of sage species across the globe.
ETHNOPHARMACOLOGICAL RELEVANCE: Salvia L. (Lamiaceae) is a diverse genus encompassing numerous species used worldwide in traditional medicine and ritualistic practices. Beyond these uses, Salvia species also hold notable ornamental and culinary value, underscoring their broad ethnobotanical significance. However, a comprehensive perspective on the global utilization of the species remains absent from the literature. AIM OF THE STUDY: This review aimed to provide the first extensive global synthesis of the ethnobotany and ethnopharmacology of the Salvia genus, offering substantial insights into
PubMed: 41401876Salvia miltiorrhiza: Traditional medicinal uses, chemistry, and pharmacology.
Salvia miltiorrhiza Bunge (SM) is a very popular medicinal plant that has been extensively applied for many years to treat various diseases, especially coronary heart diseases and cerebrovascular diseases, either alone or in combination with other Chinese plant-based medicines. Although a large number of studies on SM have been performed, they are scattered across a variety of publications. The present review is an up-to-date summary of the published scientific information about the traditional uses, chemical constituents, pharmacological effects, side effects, and drug interactions with SM, i
PubMed: 25835361[Not Available].
Nuruozak (Salvia leriifolia Benth), is a perennial herbaceous plant that is endemic to Iran and has recently been introduced as a medicinal plant. Artificial polyploidy is an efficient method to increase the production of secondary metabolites and can result in a whole spectrum of genetic, molecular and physiological modifications. In order to produce an autotetraploid population of nuruozak, various concentrations of colchicine (0.00, 0.05, 0.10, 0.20 or 0.50 % w/v) were applied to the seeds and shoot apical meristems of young seedlings at the fourth leaf-stage. Microscopic studies, flow cyto
PubMed: 30484613Contexto Científico
Los resultados clasificaron los efectos adversos en niveles: severos, moderados y menores. La evidencia actual sugiere que, si bien existen compuestos con propiedades antioxidantes, neuroprotectoras y antiinflamatorias, la transición de la medicina tradicional a la medicina basada en evidencia requiere estudios clínicos controlados de mayor escala para garantizar la seguridad y la dosificación exacta.
Seguridad y Precauciones
En relación con el embarazo y la lactancia, no existe evidencia científica suficiente que garantice la seguridad del consumo de Salvia (Salvia tchihatcheffii) en mujeres gestantes o lactantes. Debido a que muchas especies del género Salvia poseen compuestos bioactivos que pueden cruzar la barrera placentaria o excretarse en la leche materna, se recomienda evitar su uso preventivo durante estas etapas para evitar posibles efectos sobre el desarrollo fetal o neonatal. En el caso de niños menores de 12 años, el uso debe ser estrictamente evitado, ya que los sistemas enzimáticos y metabólicos de los infantes son inmaduros, lo que aumenta el riesgo de toxicidad por compuestos secundarios de la planta. Respecto a las interacciones farmacológicas, se debe tener precaución con la warfarina y otros anticoagulantes, debido al riesgo de alteraciones en la cascada de coagulación si la planta posee propiedades antiplaquetarias. Asimismo, si el usuario consume fármacos para la diabetes como la metformina, existe un riesgo de hipoglucemia (descenso excesivo de azúcar en sangre) si la planta posee efectos hipoglucemiantes. En pacientes bajo tratamiento con antihipertensivos, la interacción podría potenciar la disminución de la presión arterial, provocando hipotensión.
Otras plantas estudiadas para Estrés oxidativo
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