Chachacoma para Inflamación
Senecio nutans — 5 estudios científicos revisados
Preliminary¿Sirve Chachacoma para inflamación?
Propiedades antiinflamatorias naturales
Compuestos activos involucrados: Alcaloides, Fenoles, Flavonoides, Terpenos, Compuestos fenólicos
Evidencia Científica
Los siguientes estudios han investigado la relación entre Chachacoma y inflamación:
Protective Effects of Qingre Sanjie Jiaonang on Pulmonary Fibrosis: A Pilot Study.
BACKGROUND: Qingre Sanjie Jiaonang (QRSJ) is a single herbal preparation from Senecio scandens Buch.-Ham.ex D. Don which has been proved to have anti-inflammatory and antioxidant effects. QRSJ has been used in treating upper respiratory tract inflammation and acute bronchitis in China for nearly twenty years. PURPOSE: This study aims to explore the potential effects of QRSJ in alleviating pulmonary fibrosis (PF) and its mechanisms. STUDY DESIGN AND METHOD: A mouse model of PF was induced by intratracheal injection of Bleomycin (BLM, 5 mg/kg), followed by different doses of QRSJ administration
PubMed: 40191096Integrating serum pharmacochemistry, network pharmacology and untargeted metabolomics strategies to reveal the material basis and mechanism of action of Feining keli in the treatment of chronic bronchitis.
ETHNOPHARMACOLOGICAL RELEVANCE: Feining keli (FNKL) is herbal preparation mainly made from Senecio cannabifolius Less., In recent years, more and more studies have found that FNKL has excellent therapeutic effects on chronic bronchitis (CB). Nevertheless, its pharmacodynamic material basis and mechanism of action are still unknown. AIM OF THE STUDY: This study aimed to explore the pharmacodynamic material basis and mechanism of action of FNKL in treating CB. MATERIALS AND METHODS: The CB rat model was induced using nasal drops of lipopolysaccharide (LPS) in combination with smoking. Various as
PubMed: 39089660Senecio scandens Buch.-Ham.: a review on its ethnopharmacology, phytochemistry, pharmacology, and toxicity.
ETHNOPHARMACOLOGICAL RELEVANCE: The aerial parts of Senecio scandens Buch.-Ham. (family Asteraceae) have a long history in traditional Chinese medicine as a treatment for various ailments, such as bacterial diarrhea, enteritis, conjunctivitis, and respiratory tract infections. MATERIALS AND METHODS: A bibliographic investigation of Senecio scandens was accomplished by analyzing secondary sources, including the Chinese Medicinal plantal Classics, the Internet (Google Scholar and Baidu Scholar), and scientific databases accepted worldwide (Pubmed, Scopus, Web of Science, SciFinder, and CNKI). Th
PubMed: 23747644Occurrence and biological activities of eremophilane-type sesquiterpenes.
As important members of the terpenes family, sesquiterpenes represent a group of natural compounds with diverse skeletal types. Among them, the eremophilane-type sesquiterpenes, widely present in several genera (such as Ligularia, Senecio, Cacalia) of Asteraceae, account for a small number of natural compounds and form differently from other sesquiterpenes because they challenged the isoprene rule of biosynthesis. Due to the unique structural features and various functional groups, these compounds possess a number of biological activities such as anti-tumor, anti-bacterial and anti-inflammator
PubMed: 25138093Genus Senecio in China: A review on its traditional uses, phytochemistry, pharmacology, and toxicity.
ETHNOPHARMACOLOGICAL RELEVANCE: The genus Senecio comprises approximately 1500 species worldwide, with over 60 species distributed throughout China. These plants have been widely used in traditional Chinese medicine to treat various conditions including inflammation, eye diseases, vaginal trichomoniasis, and acute urinary tract infections. AIM OF THE REVIEW: This review aims to provide a comprehensive analysis of the geographical distribution, traditional uses, phytochemical composition, pharmacological activities, and toxicology of medicinally important Senecio species in China. Furthermore,
PubMed: 40158830Seguridad y Precauciones
Seguridad y precauciones El uso de la chachacoma (*Senecio nutans*) debe realizarse con extrema precaución y bajo una supervisión profesional rigurosa, debido a la complejidad de sus componentes químicos y sus efectos biológicos. Aunque es una planta ampliamente utilizada en las comunidades andinas para el mal de altura, su perfil de seguridad requiere un manejo cuidadoso. En cuanto a las contraindicaciones, no se recomienda el consumo de chachacoma en mujeres embarazadas ni en periodo de lactancia. La falta de estudios clínicos que garanticen la ausencia de efectos teratogénicos o la transferencia de compuestos activos a través de la leche materna hace que su uso sea contraindicado en estos grupos vulnerables. Asimismo, su uso en niños debe evitarse debido a la ausencia de datos de seguridad que permitan establecer dosis pediátricas seguras. Respecto a los efectos secundarios y la toxicidad, es fundamental considerar que los extractos de esta especie pueden inducir efectos sobre el sistema cardiovascular.
Otras plantas estudiadas para Inflamación
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