Barbatimão para Estrés oxidativo
Stryphnodendron barbatimam — 8 estudios científicos revisados
Traditional¿Sirve Barbatimão para estrés oxidativo?
En estudios in vitro, se ha demostrado que los extractos de la corteza de esta especie poseen una potente actividad antioxidante y citotóxica selectiva.
Compuestos activos involucrados: Flavonoides, Taninos, Terpenos, Compuestos fenólicos
Evidencia Científica
Los siguientes estudios han investigado la relación entre Barbatimão y estrés oxidativo:
Influence of extracts of Stryphnodendron polyphyllum Mart. and Stryphnodendron obovatum Benth. on the cicatrisation of cutaneous wounds in rats.
Stem bark of the two species Stryphnodendron polyphyllum Mart. and Stryphnodendron obovatum Benth., Leguminosae, was investigated for wound healing, antibacterial and antioxidant activity. These plants contain 12 and 19% tannins in their stem bark, respectively, and are widely used in traditional medicine in Brazil. The total content of phenolics of the crude extract (CE) of Stryphnodendron obovatum was 76.95 +/- 2.98% (CV = 3.87%) and of the ethyl-acetate fraction (EAF) was 89.13 +/- 0.34% (CV = 0.38%); whereas in Stryphnodendron polyphyllum the CE phenolics content was 51.62+/-1.53% (CV = 2.
PubMed: 15894137Evidence of traditionality of Brazilian medicinal plants: The case studies of Stryphnodendron adstringens (Mart.) Coville (barbatimão) barks and Copaifera spp. (copaíba) oleoresin in wound healing.
ETHNOPHARMACOLOGICAL RELEVANCE: The World Health Organization (WHO) recognizes the potential of plants used in secular traditional medicine and considers this an important source of evidence to assess their effectiveness and safety. Brazil is rich in biodiversity and traditional uses based on the Amerindian culture. However, many processes started with the arrival of the Portuguese in the year 1500. The successive economic cycles, for example, led to destruction of native vegetation and an intense cultural erosion. As a consequence, the information about the use of plants in the past centuries
PubMed: 29501844Proanthocyanidins polymeric tannin from Stryphnodendron adstringens are active against Candida albicans biofilms.
BACKGROUND: Biofilm formation is important in Candida albicans pathogenesis and constitutes a mechanism of antifungal resistance. Thus, we evaluated the effect of proanthocyanidins polymer-rich fractions from Stryphnodendron adstringens (fraction F2 and subfraction F2.4) against C. albicans biofilms. METHODS: Firstly, the antifungal activity of F2 and F2.4 against planktonic cells of Candida albicans (ATCC 10231) was determined using broth microdilution method. Anti-biofilm effect of F2 and F2.4 was evaluated during biofilm formation or on mature biofilm of C.
PubMed: 25886244[Discovery of Novel Biologically Active Compounds of Natural Origin, with a Focus on Anti-tumor Activity].
Numerous clinically valuable medicines, including anticancer drugs, have been developed from biologically active natural compounds and their structurally related derivatives. This review discusses novel natural compounds with promising biological activities and those with novel chemical structures. Glaziovianin A, an isoflavone isolated from the leaves of Ateleia glazioviana (Legminosae), inhibited cell cycle progression at the M-phase with an abnormal spindle structure. AU-1 and YG-1, 5β-steroidal glycosides isolated from the whole plants of Agave utahensis and the underground parts of Yucca
PubMed: 26423865Stryphnodendron adstringens: Clarifying Wound Healing in Streptozotocin-Induced Diabetic Rats.
Diabetes mellitus is a serious public health problem in which a major complication is impaired wound healing. Among the strategies developed to foster tissue repair is the use of medicinal plants. The bark of Stryphnodendron adstringens, which is popularly used as an aid in wound healing, has a documented effect on wound repair in normal rats. This study evaluated the healing action of the crude extract of S. adstringens in diabetic rats, and its chemical content.
PubMed: 26218337Contexto Científico
El mecanismo identificado sugiere que los polímeros de taninos pueden desestabilizar la matriz del biopelícula, lo que representa una estrategia prometedora para combatir infecciones fúngicas persistentes [PMID 25886244].
Seguridad y Precauciones
Seguridad y Precauciones del Barbatimão (Stryphnodendron barbatimam) El uso de la corteza de Barbatimão debe realizarse con precaución, ya que su alta concentración de taninos puede generar efectos sistémicos si no se administra correctamente. A continuación, se detallan los perfiles de seguridad para su uso: Embarazo y Lactancia: No existen estudios clínicos suficientes que garanticen la inocuidad del Barbatimão en mujeres gestantes o en periodo de lactancia. Debido a la falta de evidencia sobre su paso a la leche materna y su potencial efecto sobre el desarrollo fetal, su uso está contraindicado en estas etapas. Niños y Lactantes: El uso en población pediátrica no está recomendado. La piel de los niños es más permeable y los órganos en desarrollo son más sensibles a la absorción de compuestos astringentes y taninos potentes presentes en la planta. Interacciones con Fármacos: El mecanismo de interacción principal se centra en su capacidad para alterar la absorción de otros medicamentos.
Otras plantas estudiadas para Estrés oxidativo
Perfil completo: Ver todos los usos y evidencia de Barbatimão →