Ahuehuete para dolor articular
Taxodium mucronatum — 5 estudios científicos revisados
Preliminary¿Sirve Ahuehuete para dolor articular?
Se utiliza de forma tópica para mitigar la inflamación en las articulaciones.
Compuestos activos involucrados: Lípido, Taxodiona, Terpenos, Isopreno
Evidencia Científica
Los siguientes estudios han investigado la relación entre Ahuehuete y dolor articular:
Climate sensitivity of seasonal radial growth in young stands of Mexican conifers.
Alteration of forest by climate change and human activities modify the growth response of trees to temperature and moisture. Growth trends of young forests with even-aged stands recruited recently when the climate became warmer and drier are not well known. We analyze the radial growth response of young conifer trees (37-63 years old) to climatic parameters and drought stress employing Pearson correlations and the Vaganov-Shashkin Lite (VS-Lite) model. This study uses tree rings of six species of conifer trees (Pinus teocote, Pinus pseudostrobus, Pinus pinceana, Pinus montezumae, Pinus ayacahu
PubMed: 35672588Physical environmental conditions determine ubiquitous spatial differentiation of standing plants and seedbanks in Neotropical riparian dry forests.
Mexican tropical dry forests are remarkably extensive and floristically diverse despite manifesting alarming rates of deforestation. Riparian habitats within dry forests provide critical ecological benefits that may mitigate negative impacts, but processes underlying riparian functions are still not well understood. We identified physical environmental conditions affecting the composition and abundance of standing vegetation assemblages and woody and herbaceous components in soil seedbank assemblages of riparian corridors in central Mexico using mainly NMDS ordination techniques, permuted anal
PubMed: 30865660Taxodione induces apoptosis in BCR-ABL-positive cells through ROS generation.
Chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL) are hematopoietic malignancies caused by the constitutive activation of BCR-ABL tyrosine kinase. Although direct BCR-ABL inhibitors, such as imatinib, were initially successful in the treatment of leukemia, many patients developed drug resistance over time due to the gatekeeper mutation of BCR-ABL T315I. In the present study, we found that taxodione, a quinone methide diterpene isolated from Taxodium distichum, significantly induced apoptosis in human myelogenous leukemia-derived K562 cells, which were transformed by BCR-ABL
PubMed: 29859988Antifungal abietane-type diterpenes from the cones of Taxodium distichum Rich.
The chemical composition of Taxodium distichum cones and the antifungal activities of twelve diterpenoids against two wood decay fungi, Trametes versicolor (white-rot) and Fomitopsis palustris (brown-rot) were examined. The chemical composition of the major extractive fraction, the n-C(6)H(14) extract, was evaluated and its antifungal properties were identified. Twelve diterpenoids including ten abietane-type components were isolated from the n-C(6)H(14) extract: 6,7-dehydroferruginol (1), ferruginol (2), 6,7-dehydroroyleanone (3), sandaracopimaric acid (4), taxodione (5), taxodal (6), taxodon
PubMed: 21072573In vitro and in vivo antitumor effects of the diterpene-enriched extract from Taxodium ascendens through the mitochondrial-dependent apoptosis pathway.
Extracts and components of Taxodium ascendens Brongn, an excellent afforestation tree, have exhibited several activities, including antibacterial activity and inhibitory activity on carbonic anhydrase II. However, the anti-hepatocellular carcinoma (anti-HCC) activity of extracts from the leaves of T. ascendens (TALE) remains unclear. In the present study, six diterpenoid compounds were isolated from a TALE extract. Here, the pro-apoptotic activities and the molecular mechanisms of TALE and the compounds 1-6 on HepG2 and Hep3B HCC cells were evaluated.
PubMed: 29239817Seguridad y Precauciones
El uso de Taxodium mucronatum (Ahuehuete) debe abordarse con extrema cautela debido a la presencia de metabolitos secundarios con actividad biológica significativa, como diterpenos y esteroles, que han mostrado efectos citotóxicos en estudios in vitro (PMID 41823025). En el caso de mujeres embarazadas y en periodo de lactancia, no existe evidencia clínica que garantice la seguridad del consumo de preparados derivados de esta especie; por el contrario, la actividad citotóxica observada en compuestos aislados de la planta sugiere un riesgo potencial de interferencia con la división celular normal, lo que podría comprometer el desarrollo fetal o afectar la salud del lactante a través de la transferencia de metabolitos. Para niños menores de 12 años, el uso está estrictamente contraindicado debido a que sus sistemas metabólicos y de desintoxicación hepática están en desarrollo, lo que los hace más susceptibles a los efectos de los diterpenos y compuestos citotóxicos identificados (PMID 41823025). En cuanto a las interacciones farmacológicas, el uso de Ahuehuete podría interferir con la warfarina (anticoagulante) debido a posibles efectos sobre las vías de señalización celular o la actividad enzimática hepática, incrementando el riesgo de hemorragias. Asimismo, existe un riesgo de interacción con la metformina (antidiabético) si los compuestos de la planta alteran la sensibilidad a la insulina o el metabolismo glucídico. El uso de antihipertensivos también debe evitarse, ya que la actividad de los esteroles y otros metabolitos podría potenciar o inhibir de forma impredecible la respuesta vascular.
Otras plantas estudiadas para dolor articular
Perfil completo: Ver todos los usos y evidencia de Ahuehuete →