Borraja de monte para Inflamación
Tournefortia scabrida — 4 estudios científicos revisados
Traditional¿Sirve Borraja de monte para inflamación?
Cataplasmas de hojas para inflamaciones locales, con posible acción antiinflamatoria de los compuestos fenólicos.
Compuestos activos involucrados: Flavonoides, Taninos, Saponinas, Alcaloides pirrolizidínicos, Ácido rosmarínico, Mucílagos, Alcaloides, Kaempferol, Quercetina, ácido cafeico, Compuestos fenólicos
Evidencia Científica
Los siguientes estudios han investigado la relación entre Borraja de monte y inflamación:
Tournefortia sarmentosa extract attenuates acetaminophen-induced hepatotoxicity.
CONTEXT: Tournefortia sarmentosa Lam. (Boraginaceae), a Chinese herbal medicine, is commonly used as a detoxicant or anti-inflammatory agent. OBJECTIVE: As acetaminophen (APAP) is a well-known hepatotoxin, we investigated the effect of the aqueous extract of the T. sarmentosa on APAP-induced hepatotoxicity in vivo and in vitro. MATERIALS AND METHODS: Levels of liver function markers serum glutamate oxaloacetate transaminase (SGOT), glutamate pyruvate transaminase (SGPT), and alkaline phosphatase (ALP), inflammatory markers tumor necrosis factor (TNF)-α, interleukin (IL)-1b, and IL-6 in serum,
PubMed: 22085220Effect of aqueous extract of Tournefortia sarmentosa on the regulation of macrophage immune response.
Tournefortia sarmentosa, a Chinese herbal medicine, is considered an antioxidant or a detoxicant agent. Recent studies have shown that T. sarmentosa plays an important role in inhibiting low-density-lipoprotein oxidation and attenuating acetaminophen-induced hepatotoxicity. However, information regarding the signaling mechanism of T. sarmentosa-mediated immunoregulation is still limited.
PubMed: 24157329Antiviral effects of the petroleum ether extract of
Enterovirus 71 (EV71) is the major cause of severe hand, foot, and mouth disease (HFMD). Compared to other HFMD pathogens, like coxsackievirus A16 (CVA16), EV71 can invade the central nervous system and cause permanent damage. At present, there are no available antivirals against EV71 for clinical treatment. Herein, multiple Chinese botanical drugs were collected, and 47 types of botanical extracts were extracted using aqueous solutions and organic solvents. Based on the cytopathic effect inhibition assay, petroleum ether extract of
PubMed: 36523495The caffeic acid in aqueous extract of Tournefortia sarmentosa enhances neutrophil phagocytosis of Escherichia coli.
Tournefortia sarmentosa, a Chinese herbal medicine, is considered an antioxidant or a detoxicating agent. Recently T. sarmentosa has received attention for its effects on the immune response. Here we provide evidence that aqueous extract of T. sarmentosa can induce increased phagocytic uptake of Escherichia coli by differentiated HL-60 cells and by neutrophils.
PubMed: 25311172Seguridad y Precauciones
La seguridad del uso de Tournefortia scabrida no ha sido evaluada en estudios formales, lo que requiere extrema precaución. La principal preocupación de seguridad con las especies de Tournefortia es la posible presencia de alcaloides pirrolizidínicos (AP), compuestos hepatotóxicos comunes en la familia Boraginaceae. Los AP pueden causar enfermedad venooclusiva hepática, fibrosis y, en exposiciones prolongadas, carcinogénesis hepática. Hasta que se confirme o descarte la presencia de AP en T. scabrida, se debe evitar el uso prolongado o en dosis elevadas. Durante el embarazo y la lactancia, el uso está estrictamente contraindicado por la ausencia de datos de seguridad y por el riesgo potencial de AP, que son teratogénicos en modelos animales.
Otras plantas estudiadas para Inflamación
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