Capitaneja para Cáncer
Verbesina crocata — 5 estudios científicos revisados
Preliminary¿Sirve Capitaneja para cáncer?
En lenguaje simple, esto significa que la planta mostró capacidad para detener células dañinas en un tubo de ensayo, pero esto no garantiza que sea segura o efectiva para tratar el cáncer en una persona.
Compuestos activos involucrados: Alcaloides, Flavonoides, Saponinas, Terpenos
Evidencia Científica
Los siguientes estudios han investigado la relación entre Capitaneja y cáncer:
Anti-inflammatory and antiproliferative evaluation of 4β-cinnamoyloxy,1β,3α-dihydroxyeudesm-7,8-ene from Verbesina persicifolia and derivatives.
The anti-inflammatory and antiproliferative activities of 4β-cinnamoyloxy,1β,3α-dihydroxyeudesm-7,8-ene (1) and of three derivatives, namely diacetate (2), hydrogenate (3) and diacetate hydrogenate (4) were evaluated. All derivatives exert an anti-inflammatory effect significantly lower than that exerted by 1. Otherwise, both the lead compound and 2-4 showed a comparable antiproliferative activity on human tumor cell lines. The investigation of the mechanism of action accountable for cytotoxicity highlighted the capacity to impair mitochondrial functions through two different pathways, dependi
PubMed: 26190458Texas Native Plants Yield Compounds with Cytotoxic Activities against Prostate Cancer Cells.
There remains a critical need for more effective therapies for the treatment of late-stage and metastatic prostate cancers. Three Texas native plants yielded three new and three known compounds with antiproliferative and cytotoxic activities against prostate cancer cells with IC50 values in the range of 1.7-35.0 μM. A new sesquiterpene named espadalide (1), isolated from Gochnatia hypoleuca, had low micromolar potency and was highly effective in clonogenic assays. Two known bioactive germacranolides (2 and 3) were additionally isolated from G. hypoleuca.
PubMed: 26785306Verbesina encelioides: cytotoxicity, cell cycle arrest, and oxidative DNA damage in human liver cancer (HepG2) cell line.
BACKGROUND: Cancer is a major health problem and exploiting natural products have been one of the most successful methods to combat this disease. Verbesina encelioides is a notorious weed with various pharmacological properties. The aim of the present investigation was to screen the anticancer potential of V. encelioides extract against human lung cancer (A-549), breast cancer (MCF-7), and liver cancer (HepG2) cell lines. METHODS: A-549, MCF-7, and HepG2 cells were exposed to various concentrations of (10-1000 μg/ml) of V.
PubMed: 27161012Antiprotozoal activity of major constituents from the bioactive fraction of Verbesina encelioides.
The bioactive petroleum ether fraction of Verbesina encelioides, previously studied by the authors, was chosen for the isolation of antiprotozoal metabolites. Pseudotaraxasterol-3β-acetate (1), benzyl 2,6-dimethoxy benzoate (2), 16β-hydroxy-pseudotaraxasterol-3β-palmitate (3) and pseudotaraxasterol (4), in addition to β-sitosterol glucoside (5) and β-sitosterol galactoside (6) were isolated and identified based on one-dimensional and two-dimensional spectral analysis. This is the first report describing (3) and (6) in genus Verbesina. The isolated compounds were tested in vitro against Plasmod
PubMed: 27154232Cytotoxicity of Nine Medicinal Plants from San Basilio de Palenque (Colombia) on HepG2 Cells.
The utilization of plants with medicinal properties is deeply rooted in the traditional knowledge of diverse human populations. This study aims to investigate the cytotoxicity of nine plants commonly used by communities in San Basilio de Palenque, Bolivar (Colombia), for managing inflammation-related illnesses. Hydroethanolic extracts from various plant parts such as roots, stems, barks, or leaves were prepared through a process involving drying, powdering, and maceration in an ethanol-water (7:3) solution. The extracts were subsequently freeze-dried and dissolved in DMSO for the bioassays. Cy
PubMed: 37514300Contexto Científico
La pregunta de investigación era si los compuestos de Verbesina crocata podían inhibir el crecimiento de células cancerosas [PMID 11520203]. El método consistió en exponer células de carcinoma humano a diferentes concentraciones del extracto etanólico de la planta.
Seguridad y Precauciones
Consulte a un profesional de salud antes de utilizar Capitaneja para cáncer. La información presentada es de carácter educativo y no sustituye el consejo médico profesional.
Otras plantas estudiadas para Cáncer
Perfil completo: Ver todos los usos y evidencia de Capitaneja →