Epená para Tos y afecciones respiratorias
Virola theiodora — 3 estudios científicos revisados
Moderate¿Sirve Epená para tos y afecciones respiratorias?
Uso documentado en la medicina tradicional y respaldado por investigación preliminar
Compuestos activos involucrados: Terpenos, Fenoles, Aceite esencial, Polifenoles, Esteroides, Saponinas, Alcaloides, Taninos
Evidencia Científica
Los siguientes estudios han investigado la relación entre Epená y tos y afecciones respiratorias:
Evaluation of Virola oleifera activity in musculoskeletal pathologies: Inhibition of human multiple myeloma cells proliferation and combination therapy with dexamethasone or bortezomib.
ETHNOPHARMACOLOGICAL RELEVANCE: Virola oleifera (Schott) A.C. Smith, Myristicaceae, has been widely used in traditional medicine in Brazil to treat rheumatic pain, joint tumours, skin diseases, halitosis, bronchial asthma, haemorrhoids, and intestinal worms. Recently, research data showed the antioxidant properties in several oxidative stress-related models. However, there is no experimental evidence supporting its potential use in managing rheumatic diseases and bone malignancies. AIMS OF THE STUDY: To evaluate the therapeutic potential of the resin from Virola oleifera in joint and bone dise
PubMed: 33609728Resin from Virola oleifera Protects Against Radiocontrast-Induced Nephropathy in Mice.
Contrast-induced nephropathy (CIN) is an iatrogenic medical event for which there is not yet a successful therapy. Increasing evidence in rodents has suggested that this disease is associated with renal tubular and vascular injury that is triggered directly by oxidative stress. In the present study, we evaluated whether the antioxidant resin from Virola oleifera (RV) could attenuate renal damage in an experimental mouse model of CIN. Adult male Swiss mice were divided into six groups and pre-treated orally with RV (10, 100 and 300 mg/kg), N-acetylcysteine (200 mg/kg) or vehicle for 5 days befo
PubMed: 26674346Anti-leishmanial activity of neolignans from Virola species and synthetic analogues.
Surinamensin, a neolignan isolated from Virola surinamensis, 3,4,5-trimethoxy-8-[2',6'-dimethoxy-4'-(E)-propenylphenoxy]-phenylpropane, a neolignan isolated from Virola pavonis, and 25 of its synthetic analogues or correlated substances with ether linkages and their corresponding C-8 sulphur and nitrogen analogues, were tested for activity against Leishmania donovani amastigotes and promastigotes in vitro. Some were active against L. donovani promastigotes at 30 microM but inactive against intracellular amastigotes. The natural neolignan from V. pavonis was active against promastigotes at 100
PubMed: 11130669Contexto Científico
The results showed that the resin improved renal function, lowered mortality, and reduced oxidative stress and cell death (apoptosis) in the kidney tissues.
Seguridad y Precauciones
La seguridad del uso de la resina de Epená (Virola theiodora) es un tema de extrema precaución debido a su complejidad química y su uso tradicional como enteógeno. No existen dosis terapéuticas estandarizadas para humanos, lo que eleva el riesgo de toxicidad accidental. En el caso de mujeres embarazadas o en periodo de lactancia, el uso de esta planta está estrictamente contraindicado. Debido a que los compuestos presentes (como flavonoides y lignanos) pueden atravesar la barrera placentaria o segregarse en la leche materna, existe un riesgo potencial de alteraciones en el desarrollo neurosensorial del feto o del lactante. La falta de estudios de seguridad en etapas de desarrollo humano hace que cualquier exposición sea un riesgo inaceptable. Para niños menores de 12 años, el uso es absolutamente contraindicado.
Otras plantas estudiadas para Tos y afecciones respiratorias
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