Vitis para Alopecia androgenética
Vitis shuttleworthii — 11 estudios científicos revisados
Preliminary¿Sirve Vitis para alopecia androgenética?
Los extractos de semillas de Vitis pueden contener compuestos que ayudan a inhibir la enzima 5-alfa reductasa, la cual convierte la testosterona en dihidrotestosterona (DHT), responsable de la miniaturización del folículo piloso.
Compuestos activos involucrados:
Evidencia Científica
Los siguientes estudios han investigado la relación entre Vitis y alopecia androgenética:
An overview of herbal alternatives in androgenetic alopecia.
The second most common alopecia-Androgenetic alopecia (AGA)-occurs due to hormonal imbalance. Dihydrotestosterone (DHT) an androgenic hormone is a sex steroid, produced in the gonads. The target sites of DHT are similar to that of testosterone, and it attaches easily remaining bound for 53 minutes as compared to 35 minutes of testosterone. Excess of DHT causes miniaturization of hair reducing the anagen phase and increasing the telogen phase leading to hair loss. Normally up to ten percent of testosterone in the body irreversibly gets converted into DHT by the action of enzyme 5-alpha-reductas
PubMed: 30980598Anti-Aging Potential of Phytoextract Loaded-Pharmaceutical Creams for Human Skin Cell Longetivity.
The exposure to ultraviolet radiations (UVR) is the key source of skin sunburn; it may produce harmful entities, reactive oxygen species (ROS), leading to aging. The skin can be treated and protected from the injurious effects of ROS by using various pharmaceutical formulations, such as cream. Cream can be loaded with antioxidants to quench ROS leading to photo-protective effects. Moreover, modern medicines depend on ethnobotanicals for protection or treatment of human diseases. This review article summarizes various in vivo antioxidant studies on herbal creams loaded with phyto-extracts.
PubMed: 26448818Global guideline for the diagnosis and management of candidiasis: an initiative of the ECMM in cooperation with ISHAM and ASM.
Candida species are the predominant cause of fungal infections in patients treated in hospital, contributing substantially to morbidity and mortality. Candidaemia and other forms of invasive candidiasis primarily affect patients who are immunocompromised or critically ill. In contrast, mucocutaneous forms of candidiasis, such as oral thrush and vulvovaginal candidiasis, can occur in otherwise healthy individuals. Although mucocutaneous candidiasis is generally not life-threatening, it can cause considerable discomfort, recurrent infections, and complications, particularly in patients with unde
PubMed: 39956121Natural Compounds Used for Treating Hair Loss.
Hair loss or alopecia is a common dermatological condition affecting up to 2% of the world population. It is often caused by hereditary factors, such as male or female pattern baldness, but it can also result from various environmental factors, an unbalanced diet, or chronic illness. While hair loss is not life-threatening, it can cause significant anxiety, depression, and other psychological problems, ultimately impacting an individual's quality of life. Various treatments for hair loss, including both synthetic drugs, such as minoxidil and finasteride, or medicinal herbs, have been approved
PubMed: 37151166Worldwide Radiation Dose in Coronary Artery Disease Diagnostic Imaging.
IMPORTANCE: In recent decades, there has been marked worldwide growth in diagnostic testing for coronary artery disease (CAD), with several common imaging modalities exposing patients to ionizing radiation. OBJECTIVE: To examine worldwide radiation doses for patients undergoing noninvasive CAD diagnostic testing. DESIGN, SETTING, AND PARTICIPANTS: This worldwide, cross-sectional study was conducted of radiation dose from noninvasive CAD imaging in 2023, using a consecutive sample of all 19 302 adults undergoing noninvasive CAD diagnostic testing at 742 centers in 101 countries during a single
PubMed: 41739468Seguridad y Precauciones
Debido a la naturaleza bioquímica de los compuestos presentes en el género Vitis, especialmente los polifenoles como los estilbenos y flavonoides, la seguridad debe abordarse con rigor clínico. En el caso de mujeres en periodo de embarazo y lactancia, no existe evidencia científica suficiente que garantice la ausencia de efectos teratogénicos (malformaciones fetales) o alteraciones en el desarrollo del lactante mediante el consumo de extractos de Vitis. Dado que los compuestos bioactivos pueden atravesar la barrera placentaria o ser excretados en la leche materna, se recomienda evitar su uso terapéutico durante estas etapas para prevenir riesgos impredecibles. Para niños menores de 12 años, el uso debe ser estrictamente evitado, ya que los sistemas enzimáticos y metabólicos en desarrollo son más sensibles a la modulación hormonal o a la carga de antioxidantes concentrados, y no se han establecido dosis seguras para esta población pediátrica. En cuanto a las interacciones farmacológicas, el consumo de Vitis puede interferir con la terapia con warfarina y otros anticoagulantes orales; los compuestos fenólicos pueden alterar la cascada de coagulación, incrementando el riesgo de hemorragias. Asimismo, existe un riesgo de interacción con la metformina, ya que los compuestos de la planta podrían potenciar efectos hipoglucemiantes, llevando a episodios de hipoglucemia.
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