Arctium para Estrés oxidativo
Arctium lappa — 15 estudios científicos revisados
Strong¿Sirve Arctium para estrés oxidativo?
La presencia de polifenoles, flavonoides y ácidos clorogénicos actúa como un potente agente antioxidante que neutraliza radicales libres.
Compuestos activos involucrados: Cinarina, Fenoles, Flavonoides, Lignanos, Polifenoles, Quercetina, Terpenos, Compuestos fenólicos
Evidencia Científica
Los siguientes estudios han investigado la relación entre Arctium y estrés oxidativo:
Arctium lappa contributes to the management of type 2 diabetes mellitus by regulating glucose homeostasis and improving oxidative stress: A critical review of in vitro and in vivo animal-based studies.
Diabetes is a metabolic disease highly widespread worldwide, and the most common form is the type 2 diabetes mellitus (T2DM). A large number of synthetic drugs are currently available for the treatment of diabetes; however, they present various side effects and, for this reason, people are increasingly inclined to search natural alternative treatments. Among these, Arctium lappa (A. lappa) has interesting anti-diabetic activities, exerted by improving glucose homeostasis and reducing insulin-resistance. In addition, A.
PubMed: 31232489Harnessing the power of Arctium lappa root: a review of its pharmacological properties and therapeutic applications.
Arctium lappa, widely recognized as burdock, is a perennial plant that is employed in the realm of traditional Chinese medicine for a wide range of medicinal applications. The herb is rich in bioactive metabolites with therapeutic potential, encompassing polyphenolic antioxidants in its leaves, and flavonoids and fructo-oligosaccharides in its underground parts. Nutraceuticals originating from botanical sources such as Arctium lappa provide supplementary health advantages alongside their nutritional content and have demonstrated effectiveness in the prevention and management of specific ailmen
PubMed: 39162715Extraction, structure and bioactivities of polysaccharide from root of Arctium lappa L.: A review.
Arctium lappa L. root is a well-known Chinese medicine with high medicinal and food values. Arctium lappa L. root polysaccharide (ALP), as the main component and bioactive substance, has a variety of biological activities, including anti-inflammatory, antioxidant, hypoglycemic, hypolipidemic, antithrombotic, immunomodulatory activity and improvement of intestinal flora. The biological activities of polysaccharides are closely related to their structures, and different extraction and purification methods will yield different polysaccharide structures.
PubMed: 38518934Arctium lappa L. roots ameliorates cerebral ischemia through inhibiting neuronal apoptosis and suppressing AMPK/mTOR-mediated autophagy.
BACKGROUND: Arctium lappa L. roots are very popular cultivated vegetables, which possesses various pharmacological activities. Our previous studies have demonstrated that Arctium lappa L. roots exerted protective effects against H PURPOSE: The objective of the present study was to investigate the neuroprotective effects of ethyl acetate extract of Arctium lappa L. roots (EAL) and the active ingredient 4,5-O-dicaffeoyl-1-O-[4-malic acid methyl ester]-quinic acid (DCMQA) in EAL against cerebral ischemia and explore the underlying mechanism.
PubMed: 33691269Arctium lappa L. polysaccharides enhanced the therapeutic effects of nasal ectomesenchymal stem cells against liver fibrosis by inhibiting the Wnt/β-catenin pathway.
The oxidative microenvironment in fibrotic livers often diminishes the effectiveness of mesenchymal stem cells (MSCs)-based therapy. Recent research suggests that pharmacological pre-treatment could enhance the therapeutic performance of MSCs. In this study, we assessed the impact of Arctium lappa L. polysaccharides (ALP) on the biological properties of nasal ectomesenchymal stem cells (EMSCs) and investigated the augmenting effect of ALP pretreatment on EMSCs (ALP-EMSCs) for the treatment of liver fibrosis. ALP treatment demonstrated multiple biological impacts on EMSC functions regarding liv
PubMed: 38280697Contexto Científico
Los ensayos biológicos demostraron propiedades antioxidantes, antiinflamatorias y mecanismos de defensa de la mucosa gástrica.
Seguridad y Precauciones
El uso de Arctium lappa (comúnmente conocido como bardana o lampazo) requiere una vigilancia cuidadosa debido a su potencia farmacológica y su capacidad para interactuar con procesos biológicos sistémicos. En cuanto al embarazo y la lactancia, no existe evidencia clínica suficiente en humanos que garantice la seguridad del consumo de extractos de bardana en estas etapas. Debido a que el compuesto puede influir en procesos hormonales o metabólicos, y ante la falta de estudios de seguridad en sujetos gestantes, se recomienda evitar su uso para prevenir posibles efectos teratogénicos (malformaciones fetales) o alteraciones en el desarrollo del lactante. Para niños menores de 12 años, el uso debe ser estrictamente evitado; los sistemas metabólicos y renales en desarrollo son más sensibles a los compuestos bioactivos como los lignanos y polifenoles, y no se han establecido dosis seguras para esta población pediátrica. En el ámbito de las interacciones farmacológicas, la presencia de compuestos con efectos hipoglucemiantes (como los fructooligosacáridos y ácidos clorogénicos) puede potenciar el efecto de fármacos antidiabéticos como la metformina o la insulina, incrementando el riesgo de hipoglucemia (niveles peligrosamente bajos de azúcar en sangre). Asimismo, debido a su potencial efecto sobre la circulación y la respuesta inflamatoria, se debe tener precaución con la warfarina y otros anticoagulantes, ya que alteraciones en la coagulación podrían ocurrir.
Otras plantas estudiadas para Estrés oxidativo
Perfil completo: Ver todos los usos y evidencia de Arctium →