Azadirachta para Hipoglucemia
Azadirachta indica — 6 estudios científicos revisados
Moderate¿Sirve Azadirachta para hipoglucemia?
El consumo de extractos de neem puede potenciar la disminución de la glucosa en sangre, lo cual es una respuesta farmacológica a su actividad antidiabética descrita en estudios de farmacología [PMID 34562010].
Compuestos activos involucrados: Alcaloides, Azadiractina, Flavonoides, Nimbidina, Saponinas, Terpenos, Compuestos fenólicos
Evidencia Científica
Los siguientes estudios han investigado la relación entre Azadirachta y hipoglucemia:
Azadirachta indica A. Juss (neem) against diabetes mellitus: a critical review on its phytochemistry, pharmacology, and toxicology.
OBJECTIVE: We aim to provide a critical review focused on the various pharmacological activities of Azadirachta indica A. Juss related to diabetes management. We also emphasise on phytochemistry and toxicology of A. indica, which could provide a comprehensive approach for plant-based drug development in future. KEY FINDINGS: From 2784 identified studies, only 83 were considered after double screening based on the inclusion criteria.
PubMed: 34562010Anti-COVID-19 potential of
COVID-19 is caused by infection with the "severe acute respiratory syndrome coronavirus-2″ (i.e., SARS-CoV-2). This is an enveloped virus having a positive sense, single-stranded RNA genome; like the two earlier viruses SARS-CoV and the Middle East respiratory syndrome (MERS) virus. COVID-19 is unique in that, in the severe case, it has the propensity to affect multiple organs, leading to multiple organ distress syndrome (MODS), and causing high morbidity and mortality in the extreme case. In addition, comorbidities like age, cardiovascular disease, diabetes and its complications, obesity, are
PubMed: 35434432Azadirachta indica: A herbal panacea in dentistry - An update.
Azadirachta indica commonly known as Neem, is an evergreen tree. Since time immemorial it has been used by Indian people for treatment of various diseases due to its medicinal properties. It possesses anti-bacterial, anti-cariogenic, anti-helminthic, anti-diabetic, anti-oxidant, astringent, anti-viral, cytotoxic, and anti-inflammatory activity. Nimbidin, Azadirachtin and nimbinin are active compounds present in Neem which are responsible for antibacterial activity. Neem bark is used as an active ingredient in a number of toothpastes and toothpowders.
PubMed: 26009692Therapeutic Applications of Neem (Azadirachta indica): A Narrative Review.
It is no surprise that nature has provided us with many therapeutic compounds for thousands of years. Throughout history, plants and their derivatives have been used orally and locally to treat most of the diseases. In addition to providing a wealth of health benefits, Azadirachta indica stands out among all of them as one of the most universal and prolific trees. Since antiquity, this medicinal plant has been used in the Unani System of Medicine as well as in other traditional systems of medicine (Ayurveda, Homeopathic, Chinese, and European "Materia Medica") to treat a wide range of diseases
PubMed: 39447127The protective effect of
Metabolic syndrome is a condition associated with obesity, diabetes, dyslipidemia, and high blood pressure. Recently, the use of phytochemicals is suggested in the control and treatment of metabolic syndrome. The
PubMed: 33995939Contexto Científico
El primer bloque de investigación se centró en la gestión de la diabetes mellitus. En un estudio de revisión crítica (PMID 34562010), los investigadores analizaron cómo los extractos de neem afectan los niveles de glucosa en sangre, el perfil de lípidos y la resistencia a la insulina.
Seguridad y Precauciones
La seguridad del uso de Azadirachta indica (neem) es un tema de extrema importancia debido a su potente actividad biológica. En el contexto del embarazo y la lactancia, el uso de neem está estrictamente contraindicado. Según la revisión sobre sus propiedades reproductivas [PMID 34092456], se ha documentado que los compuestos de la planta poseen actividades antiovulatorias, antifertilidad y abortivas. Esto significa que el neem puede interferir con el desarrollo embrionario o inducir la interrupción del embarazo mediante mecanismos hormonales y reproductivos. Por lo tanto, las mujeres embarazadas no deben consumir extractos de neem, y se recomienda precaución en la lactancia, ya que no existen estudios suficientes que garanticen que los metabolitos de la planta no pasen a través de la leche materna y afecten el desarrollo del lactante. En cuanto a los niños menores de 12 años, el uso debe ser evitado o estrictamente supervisado por profesionales de la salud, dado que el desarrollo hormonal y metabólico en la infancia es altamente sensible a los compuestos fitoquímicos como la azadiractina.
Otras plantas estudiadas para Hipoglucemia
Perfil completo: Ver todos los usos y evidencia de Azadirachta →