Carqueja para Estrés oxidativo
Baccharis genistelloides — 11 estudios científicos revisados
Preliminary¿Sirve Carqueja para estrés oxidativo?
Se han realizado estudios in vitro (realizados en tubos de ensayo o cultivos celulares) para investigar la actividad antioxidante.
Compuestos activos involucrados: Alcaloides, Distribuido, Flavonoides, Glucósido, Glucósidos, Saponinas, Terpenos, Fenoles, Polifenoles, Terpeno
Evidencia Científica
Los siguientes estudios han investigado la relación entre Carqueja y estrés oxidativo:
Antiproliferative activity and phenotypic modification induced by selected Peruvian medicinal plants on human hepatocellular carcinoma Hep3B cells.
ETHNOPHARMACOLOGICAL RELEVANCE: The high incidence of human hepatocellular carcinoma (HCC) in Peru and the wide use of medicinal plants in this country led us to study the activity against HCC cells in vitro of somes species used locally against liver and digestive disorders. MATERIALS AND METHODS: Ethnopharmacological survey: Medicinal plant species with a strong convergence of use for liver and digestive diseases were collected fresh in the wild or on markets, in two places of Peru: Chiclayo (Lambayeque department, Chiclayo province) and Huaraz (Ancash department, Huaraz province). Altogethe
PubMed: 25701751Effect of the Cymbopogon citratus, Maytenus ilicifolia and Baccharis genistelloides extracts against the stannous chloride oxidative damage in Escherichia coli.
Stannous ion has been used in different sectors of human interest, such as in food industry and in health sciences. Much is known about stannous chloride (SnCl(2)) toxicity, although, there is no general agreement regarding its genotoxicity. Cymbopogon citratus, Maytenus ilicifolia and Baccharis genistelloides extracts have been used in popular medicine. We evaluated the influence of these crude extracts on the survival of the Escherichia coli wild type (AB 1157) strain submitted to SnCl(2) treatment. Reactive oxygen species (ROS) can be generated by a Fenton like reaction induced by SnCl(2).
PubMed: 11551478Diversity and antimicrobial potential of the culturable rhizobacteria from medicinal plant Baccharis trimera Less D.C.
Plant microbiota is usually enriched with bacteria producers of secondary metabolites and represents a valuable source of novel species and compounds. Here, we analyzed the diversity of culturable root-associated bacteria of the medicinal native plant Baccharis trimera (Carqueja) and screened promising isolates for their antimicrobial properties. The rhizobacteria were isolated from the endosphere and rhizosphere of B. trimera from Ponta Grossa and Ortigueira localities and identified by sequencing and restriction analysis of the 16S rDNA. The most promising isolates were screened for antifung
PubMed: 35499750Chemical and toxicological effects of medicinal Baccharis trimera extract from coal burning area.
The entire process of power generation, extraction, processing and use of coal strongly impact water resources, soil, air quality and biota leads to changes in the fauna and flora. Pollutants generated by coal burning have been contaminating plants that grow in area impacted by airborne pollution with high metal contents. Baccharis trimera is popularly consumed as tea, and is widely developed in Candiota (Brazil), one of the most important coal burning regions of the Brazil. This study aims to investigate the phytochemical profile, in vivo genotoxic and mutagenic potential of extracts of B. tr
PubMed: 26741544A review of biological and pharmacological activities of Baccharis trimera.
Plant-based systems continue to play an essential role in healthcare, and their use by different cultures has been extensively documented. Baccharis trimera, popularly known as carqueja, is a plant widely distributed in South America and has been traditionally used for treating several diseases particularly associated with hepatic and gastric disorders. The present study aimed to provide a general review of the available literature on phytochemical and biological data related to the species B. trimera as a potential source of new compounds with biological activity. Considering phytochemical st
PubMed: 30240600Contexto Científico
En primer lugar, se han realizado estudios in vitro (realizados en tubos de ensayo o cultivos celulares) para investigar la actividad antioxidante.
Seguridad y Precauciones
El uso de la Carqueja (Baccharis genistelloides) requiere una precaución extrema debido a la presencia de metabolitos secundarios complejos como alcaloides y saponinas, los cuales pueden tener efectos sistémicos impredecibles. En lo que respecta al embarazo y la lactancia, no existen estudios clínicos que garanticen la inocuidad de esta especie en mujeres gestantes; por lo tanto, su uso está estrictamente contraindicado. La presencia de compuestos potencialmente teratogénicos (sustancias capaces de causar malformaciones en el feto) en las familias de Asteraceae sugiere un riesgo de interferencia con el desarrollo embrionario. Asimismo, no se recomienda su consumo durante la lactancia, ya que los glucósidos y terpenos podrían excretarse en la leche materna, afectando al lactante de formas no estudiadas. Para niños menores de 12 años, el uso debe evitarse por completo, dado que sus sistemas metabólicos, específicamente la maduración de las enzimas hepáticas encargadas de la detoxificación, no están plenamente desarrollados para procesar la carga de alcaloides y saponinas de la planta. En cuanto a las interacciones farmacológicas, la Carqueja puede presentar riesgos significativos con la warfarina (anticoagulante), debido a que los flavonoides y otros compuestos podrían alterar la agregación plaquetaria o la síntesis de factores de coagulación, incrementando el riesgo de hemorragias.
Otras plantas estudiadas para Estrés oxidativo
Perfil completo: Ver todos los usos y evidencia de Carqueja →