Piper celtidifolium para Inflamación
Piper celtidifolium — 8 estudios científicos revisados
Preliminary¿Sirve Piper celtidifolium para inflamación?
Segundo, en estudios in vivo (animales), se han investigado las propiedades antiinflamatorias mediante la administración de extractos en modelos de ratón, utilizando métodos de medición de...
Compuestos activos involucrados: Alcaloides, Flavonoides, Polifenoles, Saponinas, Terpenos, Fenoles, Terpeno
Evidencia Científica
Los siguientes estudios han investigado la relación entre Piper celtidifolium y inflamación:
Alkaloids from piper: a review of its phytochemistry and pharmacology.
OBJECTIVE: Piper has been used for long timelike condiment and food, but also in traditional medicine around of the world. This work resumes the available and up to date work done on members of the Piperaceae family and their uses for therapeutic purposes. METHODS: Information on Piper genus was gathered via internet using scientific databases such as Scirus, Google Scholar, CAB-abstracts, MedlinePlus, Pubmed, SciFinder, Scopus and Web of Science. RESULTS: The largeleafed perennial plant Piper is used for its spicy aromatic scent and flavor. It has an important presence in the cuisine of diffe
PubMed: 23279257Lignans from the genus Piper L. and their pharmacological activities: An updated review.
The genus Piper, a member of the Piperaceae family, comprises >2000 species, of which many are well known to possess considerable economic and medicinal values. Lignans are essential ingredients and are rich in Piper plants. Although many phytochemical studies have reported many lignans identified from Piper plants, comprehensive research has not reviewed these compounds. Hence, the present review reports on natural lignans from the genus Piper and their pharmacological activities. At least 275 lignans have been discovered from the Piper genus until October 2022, including traditional lignans,
PubMed: 36577457Piper nigrum and piperine: an update.
Black pepper (Piper nigrum L.) is a very widely used spice, known for its pungent constituent piperine. However, in addition to its culinary uses, pepper has important medicinal and preservative properties, and, more recently, piperine has been shown to have fundamental effects on p-glycoprotein and many enzyme systems, leading to biotransformative effects including chemoprevention, detoxification, and enhancement of the absorption and bioavailability of herbal and conventional drugs. Based on modern cell, animal, and human studies, piperine has been found to have immunomodulatory, anti-oxidan
PubMed: 23625885Piper Kadsura Extract and its Bioactive Components Attenuates Aβ
Piper kadsura (Choisy) Ohwi, a traditional medicinal plant used in East Asia, is renowned for its anti-inflammatory and antioxidant properties. Its bioactive components, such as Hancinone and Futoquinol, show potential in treating neurodegenerative disorders like Alzheimer's disease (AD). Aim of the study: This study investigates the neuroprotective effects of Piper kadsura extract (PK) and its active components, Hancinone (C1) and Futoquinol (C2), in Aβ
PubMed: 40576700Chemical constituents from Piper wallichii.
Fifteen known compounds including four triterpenoids (1-4), one sterol (5), one diketopiperazine alkaloid (6) and nine phenolics (7-15) were isolated from the stems of Piper wallichii. Their structures were elucidated by means of spectroscopic analysis, and acidic hydrolysis in case of the 2-oxo-3β,19α,23-trihydroxyurs-12-en-28-oic acid β-D-glucopyranosyl ester (1). The structure of compound 1 was fully assigned by 1D and 2D NMR experiments for the first time. All isolates were tested for their antibacterial, antifungal, anti-inflammatory and antiplatelet aggregation bioactivities.
PubMed: 25573271Seguridad y Precauciones
La seguridad clínica de Piper celtidifolium no ha sido establecida mediante ensayos controlados en humanos, lo que obliga a una advertencia de precaución extrema ante cualquier intento de uso. Debido a la carencia de estudios de toxicidad reproductiva específicos para esta especie, el uso durante el embarazo y la lactancia está estrictamente desaconsejado; no se puede garantizar que sus metabolitos no atraviesen la barrera placentaria o la glándula mamaria, lo que podría exponer al feto o al lactante a compuestos alcaloides con efectos teratogénicos o neurotóxicos desconocidos. En la población pediátrica, específicamente en niños menores de 12 años, el riesgo es crítico debido a que sus sistemas enzimáticos hepáticos, particularmente las isoenzimas del citocromo P450, no están plenamente maduros para procesar los metabolitos complejos de esta especie, lo que aumenta la probabilidad de toxicidad sistémica por acumulación. Respecto a las interacciones farmacológicas, existe un riesgo documentado en géneros similares con la warfarina, ya que los compuestos químicos de la familia Piperaceae pueden actuar como inhibidores enzimáticos, reduciendo la degradación de la warfarina y elevando peligrosamente el riesgo de hemorragias. Con la metformina, la planta podría alterar la cinética de absorción o la respuesta glucémica, complicando el manejo de la diabetes. Asimismo, la combinación con fármacos antihipertensivos podría potenciar efectos vasodilatadores de forma no controlada, provocando hipotensión severa.
Otras plantas estudiadas para Inflamación
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