Sachaculantro para Inflamación
Eryngium foetidum — 10 estudios científicos revisados
Inhibición de cox-2, tnf-α, il-6 en estudios celulares; uso tópico tradicional para picaduras¿Sirve Sachaculantro para inflamación?
La investigación científica ha explorado el potencial de Sachaculantro (Eryngium foetidum) en relación con inflamación. Se han identificado 10 estudios relevantes que examinan esta relación.
Compuestos activos involucrados: eryngial, ácido clorogénico, flavonoides, saponinas, Aceite esencial, Alcaloides, Compartido, Cumarinas, Glucósidos, Kaempferol, Quercetina, Taninos, Terpenoides, ácido, ácido cafeico, ácidos grasos
Evidencia Científica
Los siguientes estudios han investigado la relación entre Sachaculantro y inflamación:
Eryngium foetidum suppresses inflammatory mediators produced by macrophages.
OBJECTIVE: This study assessed anti-inflammatory and antioxidant activities of E. foetidum leaf extract on LPS-activated murine macrophages. METHODS: RAW264.7 cells were pretreated with or without E. foetidum extract for 1 h prior to incubation with LPS for 24 h. Anti-inflammatory activity was evaluated with reference to iNOS, COX-2, TNF-α and IL-6 gene expression.
PubMed: 22524841Antioxidant, anti-inflammatory, and anti-apoptotic activities of saffron and eryngium honey extracts.
Saffron and Eryngium honeys are unique types of monofloral honeys collected from eastern and center of Iran. In present study, first, we investigated melissopalynological and physicochemical parameters in honey samples. Then we extracted the phenolic compounds and evaluated in vitro antioxidant by FRAP assay and anti-inflammatory activities by lipopolysaccharide induced RAW 264.7 macrophage cells. Phenolic extracts reduced nitric oxide and the secretion of the inflammatory cytokines IL-6 and TNFSF9 in the inflamed cells, and by reducing the NF-kB and increasing Nrf2 gene expression, showed an
PubMed: 40211328Eryngium foetidum L.: a review.
Eryngium foetidum L. is a biennial herb which is used extensively as a medicinal plant in most tropical regions. It is of increasing importance as a spice plant cultivated in India, Vietnam, Australia and elsewhere with well documented procedures for maximum yield. It also possesses a wide range of ethnomedicinal uses including treatment for burns, earache, fevers, hypertension, constipation, fits, asthma, stomach ache, worms, infertility complications, snake bites, diarrhea and malaria. Chemical evaluation of the leaves indicated the presence of flavonoids, tannins, a saponin and several trit
PubMed: 21062639Chemopreventive Effects of Eryngium foetidum L. Leaves on COX-2 Reduction in Mice Induced Colorectal Carcinogenesis.
To investigate the potential effects of Eryngium foetidum Linn. leaves (EF) in colitis-induced colorectal carcinogenesis in mice by azoxymethane (AOM) and dextran sulfate sodium (DSS), 39 ICR male mice were studied and divided into 6 groups. The mice were received a modified AIN-76 diet in Group 1, whereas Group 2 was given an AOM, DSS, and AIN-76 diet. Groups 3 and 4 were fed with 0.8% and 3.2% freeze-dried EF with AIN-76 diets, for 5 wk. Groups 5 and 6 were fed with 0.8% and 3.2% EF diets for 5 wk during AOM/DSS administration.
PubMed: 26771664Eryngium caeruleum: an update on ethnobotany, phytochemistry and biomedical applications.
BACKGROUND: A biennial or perennial plant of the Apiaceae family, Eryngium caeruleum M. Bieb. is traditionally used in medicine as an antitoxic, diuretic, digestive, anti-inflammatory and analgesic drug. This plant is widely distributed in temperate regions around the world. Young leaves of the plant are used in cooking as aromatic cooked vegetables in various local products in Iran.
PubMed: 36175969Seguridad y Precauciones
Eryngium foetidum se considera una planta segura y bien tolerada cuando se consume como condimento culinario alimentario, contexto en el que posee una historia milenaria y documentada de uso extensivo sin reportes publicados de toxicidad clínica relevante en la literatura médica. Para uso medicinal en infusión de hojas frescas o secas en dosis de 5 a 10 gramos por litro de agua caliente, consumiendo 2 a 3 tazas diarias según la tradición herbolaria amazónica, no se han documentado efectos adversos significativos en los estudios toxicológicos publicados. Un estudio de toxicidad crónica de 24 semanas en ratones con dosis elevadas no encontró alteraciones histopatológicas significativas en órganos principales, respaldando la seguridad del uso prolongado en dosis tradicionales [PMID 27437090]. El aceite esencial concentrado puede causar irritación gastrointestinal notable y no debe ingerirse puro ni en dosis elevadas. Precauciones importantes: personas con alergia documentada a plantas de la familia Apiaceae como zanahoria, apio, perejil, hinojo y eneldo pueden presentar reactividad cruzada alérgica potencialmente significativa. Se han descrito casos aislados de dermatitis de contacto fotoalérgica relacionada con furocumarinas presentes en el género Eryngium, aunque E.
Otras plantas estudiadas para Inflamación
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