Ortiga para Actividad antirreumática
Laportea aestuans — 5 estudios científicos revisados
Uso reconocido en trinidad y tobago, pmid 35619302¿Sirve Ortiga para actividad antirreumática?
La investigación científica ha explorado el potencial de Ortiga (Laportea aestuans) en relación con actividad antirreumática. Se han identificado 5 estudios relevantes que examinan esta relación.
Compuestos activos involucrados: {'name': 'Chrysen-2-ol', 'class': 'Compuesto policíclico'}, {'name': 'Histamina', 'class': 'Amina biógena'}, {'name': 'Quercetina', 'class': 'Flavonol'}, {'name': 'Ácido clorogénico', 'class': 'Ácido fenólico'}, {'name': 'Serotonina', 'class': 'Amina biógena'}, Alcaloides, Kaempferol, Quercetina, Rutina, Saponinas, Taninos, Terpenoides, ácido, ácido clorogénico, Estigmasterol, Sitosterol, ácido linoleico, ácidos grasos
Evidencia Científica
Los siguientes estudios han investigado la relación entre Ortiga y actividad antirreumática:
[Uptake and transport of Laportea bulbifera extract in Caco-2 cell model].
Laportea bulbifera extract is effective in resisting inflammation and shows a good therapeutic effect on rheumatoid arthritis in rats. However, the absorption characteristics of active components in L. bulbifera extract in Caco-2 cells are still unclear, which limits the in-depth development of L. bulbifera resources. The purpose of this study was to investigate the absorption and transport mechanism of the active components of L.
PubMed: 36471980Pharmacokinetic-pharmacodynamic modeling of Laportea bulbifera extract in adjuvant-induced arthritis rats via joint cavity microdialysis.
This study developed a local pharmacokinetic-pharmacodynamic (PK-PD) model for Laportea bulbifera extract (LBE) in the joint cavity of adjuvant-induced arthritis (AA) rats using microdialysis technology. A stable intra-articular microdialysis sampling system was established, and the PK behavior of LBE in the joint cavities of normal and AA rats was compared using ultra performance liquid chromatography-tandem mass spectrometry analysis. The results demonstrated that the time to peak concentration and absorption half-life of the components were shortened in AA rats, whereas the area under the c
PubMed: 41886902Investigation of Cox-2 inhibition of Laportea decumana (Roxb). Wedd extract to support its analgesic potential.
ETHNOPHARMACOLOGICAL RELEVANCE: Itchy leaves Laportea decumana (Roxb). Wedd is an indigenous plant in Maluku, Indonesia, and is used traditionally to treat complaints such as fatigue and joint and muscle pains. AIM OF THE STUDY: To provide scientific proof of the analgesic effect of L. decumana ethanolic extract tested in in vivo assays while investigating its bioactive phytochemicals using liquid chromatography tandem high-resolution mass spectrometry (LC-HRMS) profiling and Cox-2 inhibition assay. MATERIALS AND METHODS: To investigate the analgesic activity of the ethanolic extract, assays w
PubMed: 37453622Antinociceptive activity of Laportea species mediated by anti-inflammatory and antioxidant mechanisms: a systematic review and meta-analysis of in vivo animal studies.
BACKGROUND: METHODS: PubMed, Scopus, ScienceDirect, EBSCO, and Google Scholar were systematically searched for in vivo animal experiments, examining RESULTS: There were sixteen studies included. Extracts of CONCLUSION: The antinociceptive activity of SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12906-026-05262-0.
PubMed: 41634700Spectrum-effect relationship of antioxidant and anti-inflammatory activities of Laportea bulbifera based on multivariate statistical analysis.
Laportea bulbifera, named Hong He Ma in Chinese, is a Chinese herbal medicine commonly used by the Miao nationality of China. In this study, 43 batches of L. bulbifera were collected from different origins in China. Ethanol, ethyl acetate and petroleum ether were used to prepare different extracts of the plant. UHPLC technique was used to establish the fingerprints, whereas DPPH assay and RAW264.7 inflammatory cell models were used to evaluate the antioxidant and anti-inflammatory activities, respectively.
PubMed: 31692001Seguridad y Precauciones
El principal riesgo inmediato de Laportea aestuans es la dermatitis de contacto provocada por los tricomas urticantes de la planta fresca. El contacto directo con la piel causa dolor intenso, enrojecimiento, edema localizado y formación de habones que pueden persistir durante varias horas a días. En personas sensibles o alérgicas, la reacción puede ser más severa, requiriendo tratamiento con antihistamínicos o corticoides tópicos. Para uso interno, las hojas secas o hervidas pierden su capacidad urticante (la histamina y la acetilcolina se degradan con el calor y la desecación) y se consideran seguras en las dosis tradicionales. Sin embargo, no existen estudios formales de toxicidad. La manipulación de la planta fresca debe realizarse con guantes protectores.
Otras plantas estudiadas para Actividad antirreumática
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