Miconia para Dolor
Miconia langsdorffii — 7 estudios científicos revisados
Traditional¿Sirve Miconia para dolor?
Diversas especies de Miconia se utilizan en la medicina popular brasileña como analgésico para dolores musculares y articulares.
Compuestos activos involucrados: Flavonoides, Taninos, Triterpenos, Ácido ursólico, Compuestos fenólicos
Evidencia Científica
Los siguientes estudios han investigado la relación entre Miconia y dolor:
Anti-inflammatory and antinociceptive activities of the leaf methanol extract of Miconia minutiflora (Bonpl.) DC. and characterization of compounds by UPLC-DAD-QTOF-MS/MS.
Some species of the genus Miconia are used in Brazilian folk medicine as analgesic and anti-inflammatory; however, several species of this genus are still poorly studied. Therefore, the aims of this study were to investigate the phytochemistry characterization by UPLC-DAD-QTOF-MS/MS, acute toxicity, anti-inflammatory and antinociceptive properties of Miconia minutiflora (Bonpl.) DC. The methanol extract of M. minutiflora (Mm-MeOH) was subjected to ultra-high-performance liquid chromatography (UPLC-DAD-QTOF-MS/MS) for the identification of the main phytocompounds. The anti-inflammatory properti
PubMed: 30215112Infusion from Miconia albicans (Melastomataceae) leaves exhibits anti-inflammatory and anti-hyperalgesic activities without toxicity.
ETHNOPHARMACOLOGICAL RELEVANCE: The leaves of Miconia albicans have been extensively used as a traditional medicine to treat inflammation, infection, arthritis, joint pain, and analgesia, which can be purchased easily. Nevertheless, the scientific evidence of chemical profile identification and toxicity investigation is meager. AIM OF THE STUDY: This study aimed to determine the chemical profile of Miconia albicans aqueous extract (MAAE), to investigate its anti-inflammatory and hyperalgesic effects, and toxicity (acute and repeated-dose oral) in vivo studies. MATERIALS AND METHODS: MAAE was o
PubMed: 36791930Miconia albicans and Curcuma longa herbal medicines positively modulate joint pain, function and inflammation in patients with osteoarthritis: a clinical study.
This study aims to evaluate the analgesic and modulating effect of Curcuma longa and Miconia albicans herbal medicines in knee's osteoarthritis (OA) treatment. This longitudinal study evaluated 24 patients with OA. The patients were divided into three groups: ibuprofen (1200 mg/day), C. longa (1000 mg/day) and M. albicans (1000 mg/day).
PubMed: 33452967Chemical profile, antioxidant and anti-inflammatory properties of Miconia albicans (Sw.) Triana (Melastomataceae) fruits extract.
ETHNOPHARMACOLOGICAL RELEVANCE: Miconia albicans (Sw.) Triana has been widely used in Brazilian popular medicine for the treatment of several diseases. Aerial parts are used as an infusion to treat arthrosis and arthritis, to relieve rheumatic and stomach pains, and intestinal disorders due to its anti-inflammatory, anti-mutagenic anti-nociceptive, digestive and hepatoprotective properties. AIM OF THE STUDY: This study aimed to characterize the of M. albicans (Sw.) Triana fruits extract (MAFRE) chemical profile and to evaluate its antioxidant, anti-inflammatory and antitumor activities, as wel
PubMed: 33647428Dereplication and quantification of the ethanol extract of Miconia albicans (Melastomaceae) by HPLC-DAD-ESI-/MS/MS, and assessment of its anti-hyperalgesic and anti-inflammatory profiles in a mice arthritis-like model: Evidence for involvement of TNF-α, IL-1β and IL-6.
ETHNOPHARMACOLOGICAL RELEVANCE: Miconia albicans (Sw) Triana (Melastomataceae), a medicinal plant widely used by practitioners of folk medicine in the northeast of Brazil, has been used to treat chronic inflammatory disorders, such as rheumatoid arthritis (RA) and other joint conditions. Oddly, there is little research on the species. AIM OF THE STUDY: We aimed to evaluate the anti-arthritic and anti-inflammatory profile of the ethanolic leaf extract of M. albicans (EEMA), as well as to perform dereplication and quantification by HPLC-DAD-ESI-/MS/MS. MATERIALS AND METHODS: The compounds presen
PubMed: 32387232Seguridad y Precauciones
La seguridad en el uso de Miconia langsdorffii es un campo con vacíos de información críticos, ya que la mayor parte de la evidencia disponible proviene de estudios in vitro (en tubos de ensayo o cultivos celulares) y no de ensayos clínicos en humanos. Debido a esta falta de estudios de toxicidad sistémica en mamíferos a largo plazo, no se ha establecido una dosis máxima terapéutica segura para el consumo humano. El uso debe ser extremadamente cauteloso. En el caso de mujeres embarazadas o en periodo de lactancia, el uso de Miconia langsdorffii está estrictamente desaconsejado. La falta de datos sobre el potencial teratogénico (capacidad de causar malformaciones fetales) y la transferencia de compuestos bioactivos, como los triterpenos (ácido ursólico y oleanólico) o flavonoides, a través de la placenta o la leche materna, representa un riesgo impredecible para el desarrollo del feto o del lactante. En niños menores de 12 años, la seguridad es igualmente desconocida; sus sistemas metabólicos y renales están en desarrollo, lo que podría alterar la excreción de los metabolitos de la planta, aumentando el riesgo de toxicidad aguda.
Otras plantas estudiadas para Dolor
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